Results 51 to 60 of about 1,555,240 (261)

A data-driven method for modeling pronunciation variation

open access: yesSpeech Communication, 2003
This paper describes a rule-based data-driven (DD) method to model pronunciation variation in automatic speech recognition (ASR). The DD method consists of the following steps. First, the possible pronunciation variants are generated by making each phone in the canonical transcription of the word optional. Next, forced recognition is performed in order
Judith M. Kessens   +2 more
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Ensemble CorrDet with adaptive statistics for bad data detection

open access: yesIET Smart Grid, 2020
Smart grid (SG) systems are designed to leverage digital automation technologies for monitoring, control and analysis. As SG technology is implemented in increasing number of power systems, SG data becomes increasingly vulnerable to cyber-attacks ...
Keerthiraj Nagaraj   +9 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Model Based Approach for Identification of Gears and Bearings Failure Modes [PDF]

open access: yesInternational Journal of Prognostics and Health Management, 2011
This paper describes the algorithms that were used for analysis of the PHM’09 gear-box. The purpose of the analysis was to detect and identify faults in various components of the gear-box. Each of the 560 vibration recordings presented a different set of
Renata Klein   +3 more
doaj  

On the surplus accuracy of data-driven energy quantification methods in the residential sector

open access: yesEnergy Informatics, 2022
Increasing trust in energy performance certificates (EPCs) and drawing meaningful conclusions requires a robust and accurate determination of building energy performance (BEP).
Lars Wederhake   +3 more
doaj   +1 more source

Data-driven Stabilization of Nitsche's Method

open access: yes
The weak imposition of essential boundary conditions is an integral aspect of unfitted finite element methods, where the physical boundary does not in general coincide with the computational domain. In this regard, the symmetric Nitsche's method is a powerful technique that preserves the symmetry and variational consistency of the unmodified weak ...
S. Saberi, L. Zhang, A. Vogel
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Data-driven methods for tracking improvement

open access: yes, 2009
The tracking precision required by modern industrial applications is continuously increasing. Feedback control alone is often no longer capable of giving the necessary tracking accuracy and so the use of two-degree-of-freedom controllers, which include a feedforward term, has become commonplace.
openaire   +1 more source

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