Results 121 to 130 of about 35,639,582 (304)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Data-driven Technologies : Challenges for Privacy and Data Protection Law

Data-driven technologies introduce new privacy risks that are currently not (explicitly) addressed by European data protection law. Against this backdrop, the chapter discusses the general conceptual shortcomings of the GDPR, followed by an overview of ...
Ebers, Martin,, Sein, Karin,
core  

Respondent-Driven Sampling and Total Population Data from a Rural Ugandan Cohort, 2010: Special Licence Access

, 2014
The study evaluated the use of Respondent Driven Sampling - a form of snowball or link-tracing sampling – to generate representative data of a rural population and compared it against existing total-population methods.
White, Richard, MRC/UVRI
core   +1 more source

Discrete element method hypoplasticity data for data-driven causal relation discovery

, 2020
This data set contains 60 true triaxial discrete element method simulations performed on granular material used for data-driven causal relation ...
Vlassis, N (via Mendeley Data), Vlassis, Nikolaos N.   +1 more
core   +1 more source

MagNet Challenge for Data-Driven Power Magnetics Modeling

IEEE Open Journal of Power Electronics
This article summarizes the main results and contributions of the MagNet Challenge 2023, an open-source research initiative for data-driven modeling of power magnetic materials.
Minjie Chen, Haoran Li, Shukai Wang, Thomas Guillod, Diego Serrano, Nikolas Forster, Wilhelm Kirchgassner, Till Piepenbrock, Oliver Schweins, Oliver Wallscheid, Qiujie Huang, Yang Li, Yu Dou, Bo Li, Sinan Li, Emmanuel Havugimana, Vivek Thomas Chacko, Sritharini Radhakrishnan, Mike Ranjram, Bailey Sauter, Skye Reese, Shivangi Sinha, Lizhong Zhang, Tom McKeague, Binyu Cui, Navid Rasekh, Jun Wang, Song Liu, Alfonso Martinez, Xinyu Liu, Chaoying Mei, Rui Zhao, Gaoyuan Wu, Hao Wu, Rui Zhang, Hao Song, Lie Zhang, Yibo Lu, Lijun Hang, Neha Rajput, Himanshu Bhusan Sandhibigraha, Neeraj Agrawal, Vishnu Mahadeva Iyer, Xiaobing Shen, Fanghao Tian, Qingcheng Sui, Jiaze Kong, Wilmar Martinez, Asier Arruti, Borja Alberdi, Anartz Agote, Iosu Aizpuru, Minmin Zhang, Xia Chen, Yuchen Dong, Duo Wang, Tianming Shen, Yan Zhou, Yaohua Li, Sicheng Wang, Yue Wu, Yongbin Jiang, Ziheng Xiao, Yi Tang, Yun-Shan Hsieh, Jian-De Li, Li-Chen Yu, Tzu-Chieh Hsu, Yu-Chen Liu, Chin-Hsien Hsia, Chen Chen, Alessio Giuffrida, Nicolo Lombardo, Fabio Marmello, Simone Morra, Marco Pasquale, Luigi Solimene, Carlo Stefano Ragusa, Jacob Reynvaan, Martin Stoiber, Chengbo Li, Wei Qin, Xiang Ma, Boyu Zhang, Zheng Wang, Ming Cheng, Wei Xu, Jiyao Wang, Youkang Hu, Jing Xu, Zhongqi Shi, Dixant Bikal Sapkota, Puskar Neupane, Mecon Joshi, Shahabuddin Khan, Bowen Su, Yunhao Xiao, Min Yang, Kai Sun, Zhengzhao Li, Reza Mirzadarani, Ruijun Liu, Lu Wang, Tianming Luo, Dingsihao Lyu, Mohamad Ghaffarian Niasar, Zian Qin, Syed Irfan Ali Meerza, Kody Froehle, Han Cui, Daniel Costinett, Jian Liu, Zhanlei Liu, Cao Zhan, Yongliang Dang, Yukun Zhang, Na Wang, Yiting Chen, Yiming Zhang, Chushan Li, Yinan Yao, Tianxiang Hu, Lumeng Xu, Yiyi Wang, Sichen Wang, Shuai Jiang, David Shumacher, Dragan Maksimovic, Ron S. Y. Hui, Johann W. Kolar, David J. Perreault, Charles R. Sullivan   +131 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Data-driven pre-design tool for Centrifugal Compressor - Supplementary data

, 2018
This dataset is linked to the following paper: V. Mounier, C. Picard, J. Schiffmann. Data-Driven Predesign Tool for Small-Scale Centrifugal Compressor in Refrigeration. ASME. J. Eng. Gas Turbines Power. 2018;140(12):121011-121011-8. doi:10.1115/1.4040845.
Mounier, V (via Mendeley Data), Mounier, Violette   +1 more
core   +1 more source

Data-Driven Filtering of the Spherical Harmonics Method

CoRR
We investigate a data-driven approach for tuning the filtered spherical harmonics method (\fpn) when solving the radiation transport equation (RTE). The \fpn method extends the classical spherical harmonics approach (\pn) by introducing regularization through a filter operator, which mitigates spurious oscillations caused by Gibbs' phenomenon.
Benjamin Plumridge, Cory D. Hauck, Steffen Schotthöfer   +2 more
openaire   +3 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source