Results 151 to 160 of about 34,112,328 (298)

A Systematic Review of Asthma Phenotypes Derived by Data-Driven Methods. [PDF]

open access: yesDiagnostics (Basel), 2021
Cunha F   +4 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Improving Data-Driven Methods to Identify and Categorize Transgender Individuals by Gender in Insurance Claims Data. [PDF]

open access: yesLGBT Health, 2022
Hughto JMW   +7 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Data-driven methods for dengue prediction and surveillance using real-world and Big Data: A systematic review. [PDF]

open access: yesPLoS Negl Trop Dis, 2022
Sylvestre E   +6 more
europepmc   +1 more source

Data-driven textile flaw detection methods

open access: yes, 2015
This research develops three efficient textile flaw detection methods to facilitate automated textile inspection for the textile-related industries. Their novelty lies in detecting flaws with knowledge directly extracted from textile images, unlike existing methods which detect flaws with empirically specified texture features.
openaire   +3 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Hospital length of stay for COVID-19 patients: Data-driven methods for forward planning. [PDF]

open access: yesBMC Infect Dis, 2021
Vekaria B   +16 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

DATASET2050 D2.2 - Data-driven Model [PDF]

open access: yes, 2016
The purpose of this document, Deliverable 2.2, is to build the structure and specifications of the DATASET2050 data driven model. The door-to-door process is complex and therefore direct performance measurement of the process cannot be done due to ...
Perez, D.   +5 more
core  

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