Results 161 to 170 of about 10,909,632 (287)

Making Accessibility Data Accessible – a Challenge

open access: yes, 2018
The Norwegian mapping authority has been carrying out a project on mapping accessibility following a national standard since 2009. In the beginning, the mapping was organized and carried out by the Norwegian Mapping Authority. This resulted in the creation of a good basic dataset for many Norwegian districts and bigger district-centers and enabled us ...
Bögelsack, Kathrin, Michaelis, Sven
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Satellites: Make data freely accessible [PDF]

open access: yesNature, 2013
Turner, W   +13 more
openaire   +3 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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