Results 161 to 170 of about 12,309,063 (288)

Quantifying the Tolerability of Antipsychotic Treatment-Related Side Effects in Schizophrenia: A Survey Study of Patients and Caregiver Proxies

open access: yesPatient Preference and Adherence
Melissa Culhane Maravic,1 Kelly Birch,1 Anh Thy H Nguyen,1 Alicia Subasinghe,2 Elizabeth Stafford,3 Christopher Zacker2 1Precision AQ, New York, NY, USA; 2Cerevel Therapeutics, Cambridge, MA, USA; 3National Alliance on Mental Illness, Arlington, VA ...
Maravic MC   +5 more
doaj  

MetaboSERV-a platform for selecting, exchanging, and visualizing metabolomics data with controlled data access. [PDF]

open access: yesGigascience
Tucholski T   +11 more
europepmc   +1 more source

Satellites: Make data freely accessible [PDF]

open access: yesNature, 2013
Turner, W   +13 more
openaire   +3 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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