Results 101 to 110 of about 25,162,578 (291)

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

PDF Data Curation Primer

, 2020
This work was created as part of the Data Curation Network “Specialized Data Curation” Workshop #2 held at Johns Hopkins University April 17-18, 2019.The purpose of this primer is to guide a data curator through the curation process for Portable Document
Contaxis, Nicole, Kriesberg, Adam, Ossom-Williamson, Peace, Lam, Margaret   +3 more
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Understanding the value of curation: A survey of US data repository curation practices and perceptions.

PLoS ONE
Data curators play an important role in assessing data quality and take actions that may ultimately lead to better, more valuable data products. This study explores the curation practices of data curators working within US-based data repositories.
Lisa R Johnston, Renata Curty, Susan M Braxton, Jake Carlson, Hannah Hadley, Sophia Lafferty-Hess, Hoa Luong, Jonathan L Petters, Wendy A Kozlowski   +8 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Data supporting “Data Sharing Readiness in Academic Institutions” Version 1.0

, 2020
One CSV datafile and a readme.txt explaining the columns used as well as the data collection methodology. Version 1.0 is the original data collected by the authors.
Johnston, Lisa R, Coburn, Liza
core   +1 more source

Linking Data and Publications: Towards a Cross-Disciplinary Approach [PDF]

, 2013
Hoogerwerf M, Lösch M, Schirrwagen J, et al. Linking Data and Publications: Towards a Cross-Disciplinary Approach. International Journal of Digital Curation.
Keramida, Dimitra, Dimitra Keramida, Najla Rettberg, Iatropoulou, Katerina, Schirrwagen, J., Sarah Callaghan, Lösch, Mathias, Lösch, Mathias ; https://orcid.org/, Rettberg, Najla, Callaghan, S., Callaghan, Sarah, Manghi, Paolo, Katerina Iatropoulou, Loesch, M., Schirrwagen, Jochen ; https://orcid.org/, Maarten Hoogerwerf, Paolo Manghi, Jochen Schirrwagen, Hoogerwerf, Maarten, Mathias Lösch, Manghi, P., Schirrwagen, Jochen, Hoogerwerf, M.L.   +22 more
core   +3 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Atlas.ti Data Curation Primer

, 2020
This work was created as part of the Data Curation Network “Specialized Data Curation” Workshop #2 held at Johns Hopkins University April 17-18, 2019.Altas.ti is a software application that allows researchers to analyze qualitative data in a systematic ...
Corral, Margarita
core  

Data Curation as Governance Practice.

Scand. J. Inf. Syst., 2020
Data governance is concerned with leveraging the potential value of data in data infrastructures. In IS research, data governance has developed as a management perspective, implying a narrow view of who makes decisions about the data in infrastructures.
Parmiggiani, Elena, Grisot, Miria
openaire   +2 more sources