Results 111 to 120 of about 25,162,578 (291)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
, 2020 This work was created as part of the “Specialized Data Curation” Workshop #2 held at Johns Hopkins University in Baltimore, MD on April 17-18, 2019.Institute of Museum and Library Services RE-85-18-0040-18Hadley, Hannah. (2020).
Hadley, Hannah
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Annual Report 2022: End of Year Highlights of the Data Curation Network
, 2023 This report showcases the numerous endeavors the DCN supports, including information about our members, our shared expertise and community of practice, research efforts, and governance.
Data Curation Network
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FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
DCN-NIH Specialized Curation for Geospatial and Scientific Images Workshop, 2025
A collection of materials used to instruct individuals how to curate scientific images and geospatial data generated as part of the NIH funded “NIH Data Management Center of Excellence (DMCOE) - Expanding Data Curation Education” project.
Kenney, Mariah +4 more
core +1 more source
, 2020 This work was created as part of the “Specialized Data Curation” Workshop #3 held at Washington University in St. Louis, MO on November 5-6, 2019.Institute of Museum and Library Services RE-85-18-0040-18Kalt, Marley; Scott, Dorris. (2020).
Kalt, Marley, Scott, Dorris
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FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
, 2020 This work was created as part of the “Specialized Data Curation” Workshop #3 held at Washington University in St. Louis, MO on November 5-6, 2019.Institute of Museum and Library Services RE-85-18-0040-18Kearney, Courtney; Ruhs, Nick; Sedlins, Mara; Tien,
Trelogan, Jessica +5 more
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SPEC Kit #354: Data Curation [PDF]
, 2017 The purpose of this survey was to uncover the current staffing and infrastructure (policy and technical) at ARL member institutions for data curation, understand the current level of demand for data curation services, and discover any challenges that ...
Olendorf, Robert +6 more
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