Results 131 to 140 of about 1,628,849 (334)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Data Curation for Information Professionals [PDF]

open access: yes, 2012
2 presentations: 1. Data Curation in a Research Library: A Start-Up Story Patricia Hswe, Penn State University (31 minutes) 2. Wading into the Data Pool: Engaging with data management without drowning...hopefully Yasmeen Shorish, James Madison ...
Hswe, Patricia, Shorish, Yasmeen
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

ELI: an IoT-aware big data pipeline with data curation and data quality. [PDF]

open access: yesPeerJ Comput Sci, 2023
de Haro-Olmo FJ   +4 more
europepmc   +1 more source

Organic Contamination Baseline Study: In NASA JSC Astromaterials Curation Laboratories. Summary Report [PDF]

open access: yes, 2013
In preparation for OSIRIS-REx and other future sample return missions concerned with analyzing organics, we conducted an Organic Contamination Baseline Study for JSC Curation Labsoratories in FY12. For FY12 testing, organic baseline study focused only on
Calaway, Michael J.
core   +1 more source

Comparing two deep learning algorithms for acute infarct segmentation on diffusion-weighted imaging in routine clinical practice

open access: yesDigital Health
Objectives Infarct volumes on diffusion-weighted imaging (DWI) are critical for predicting stroke outcomes and guiding late-window endovascular thrombectomy. Although 3D U-Net-based deep learning achieves high sensitivity, it often yields false positives
Hokyu Kim   +29 more
doaj   +1 more source

Curating Collections as Data

open access: yes, 2023
This is the first blog in a series of posts related to the Cultural Heritage Image Sharing Recommendations produced by the WorldFAIR Project’s Cultural Heritage Image Sharing Working ...
openaire   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

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