Results 71 to 80 of about 25,162,578 (291)

DCC Briefing Paper: What is digital curation?

open access: yes, 2008
There is an ever-increasing amount of data being created in digital formats, through the digitisation of existing analogue information and the creation of new 'born-digital' data from the sciences, arts, and humanities sectors.
Abbott, Daisy
core   +3 more sources

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Level of curation self-reported by 100 CoreTrustSeal certified repositories (2017-2019)

open access: yes
This dataset extracts and makes machine-actionable the responses to the "Level of curation performed" component of the CoreTrustSeal application v01 (2017-2019). The author reviewed 100 applications in pdf file format and compiled the responses into one
Johnston, Lisa R
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Checklist of CURATED Steps Performed by the Data Curation Network, v.1

open access: yes, 2018
The DCN developed a standardized set of C-U-R-A-T-E-D steps and checklists to ensure that all datasets submitted to the Network receive consistent treatment.
Data Curation Network
core  

Data Curation Network Strategic Framework 2022-2025 v1.0

open access: yes, 2022
As we grow and evolve, it’s vital that we stay true to our mission as an organization. In 2021, we began a process to outline a strategic framework for continued growth while further cementing our role within the broader data sharing community.
Data Curation Network
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

SAS Data Curation Primer [PDF]

open access: yes, 2020
This work was created as part of the “Specialized Data Curation” Workshop #3 held at Washington University in St. Louis, MO on November 5-6, 2019.Institute of Museum and Library Services RE-85-18-0040-18Xu, Qiong. (2020).
Xu, Qiong
core  

The Data Curation Network: Leveraging Expertise to Curate Data at Scale

open access: yes, 2019
The Data Curation Network launched the three-year pilot of a distributed model for the curation of research data in 2018. Good curation increases the value and impact of research data. The collaborative, networked approach of the Data Curation Network leverages the expertise across network members to enhance the local repository’s ability to curate ...
Blake, Mara, Herndon, Joel
openaire   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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