Results 71 to 80 of about 1,950,388 (266)

Timing Analysis with INTEGRAL: Comparing Different Reconstruction Algorithms

Acta Polytechnica, 2011
INTEGRAL is one of the few instruments capable of detecting X-rays above 20 keV. It is therefore in principle well suited for studying X-ray variability in this regime. Because INTEGRAL uses coded mask instruments for imaging, the reconstruction of light
V. Grinberg, I. Kreykenbohm, F. Fürst, J. Wilms, K. Pottschmidt, M. Cadolle Bel, J. Rodriguez, D. M. Marcu, S. Suchy, A. Markowitz, M. A. Nowak   +10 more
doaj  

Update of the Xylella spp. host plant database – Systematic literature search up to 31 December 2023

EFSA Journal
This scientific report provides an update of the Xylella spp. host plant database, aiming to provide information and scientific support to risk assessors, risk managers and researchers dealing with Xylella spp.
European Food Safety Authority (EFSA), Vincenzo Cavalieri, Elisa Fasanelli, Davide Gibin, Alicia Gutierrez Linares, Pierfederico La Notte, Luca Pasinato, Alice Delbianco   +7 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Semantic Data Extraction

Procedia Technology, 2015
AbstractData extractors are generally difficult to maintain. To simplify the difficult tasks of integrating new data sources and of handling structural changes within existing data sources, we have implemented a new approach called RK. RK is a tool which serves as a guide for extraction purposes; the semantic tree generated by the semantic rules (used ...
Jánosi-Rancz, Katalin Tünde, Lajos, Árpád   +1 more
openaire   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Analysis of automated modern web crawling and testing tools and their possible employment for information extraction / Šiuolaikinių tinklalapių automatizuotam naršymui ir testavimui skirtų priemonių analizė ir pritaikomumas informacijai rinkti

Mokslas: Lietuvos Ateitis, 2012
World Wide Web has become an enormously big repository of data. Extracting, integrating and reusing this kind of data has a wide range of applications, including meta-searching, comparison shopping, business intelligence tools and security analysis of ...
Tomas Grigalis, Leonardas Marozas, Lukas Radvilavičius   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source