Results 131 to 140 of about 5,937,551 (333)

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

Children's cognitive reflection predicts successful interpretations of covariation data

open access: yesFrontiers in Developmental Psychology
IntroductionCognitive reflection is the ability and disposition to reflect on one's own thinking, allowing a person to identify and correct judgments grounded in intuition rather than logic.
Andrew G. Young, Andrew Shtulman
doaj   +1 more source

Autonomous exploration system: Techniques for interpretation of multispectral data [PDF]

open access: yes
An on-board autonomous exploration system that fuses data from multiple sensors, and makes decisions based on scientific goals is being developed using a series of artificial neural networks.
Eberlein, Susan, Yates, Gigi
core   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

Probabilistic Method to Fuse Artificial Intelligence-Generated Underground Utility Mapping

open access: yesSensors
Utility as-built plans, which typically provide information about underground utilities’ position and spatial locations, are known to comprise inaccuracies.
Kunle Sunday Oguntoye   +5 more
doaj   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

open access: yesMolecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo   +11 more
wiley   +1 more source

Machine Learning-Based Objective Evaluation Model of CTPA Image Quality: A Multi-Center Study

open access: yesInternational Journal of General Medicine
Qihang Sun,1 Zhongxiao Liu,1 Tao Ding,1 Changzhou Shi,2 Nailong Hou,2 Cunjie Sun1 1Department of Medical Imaging, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, People’s Republic of China; 2School of Medical Imaging, Xuzhou Medical ...
Sun Q   +5 more
doaj  

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