Results 121 to 130 of about 32,390,911 (232)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Essential Aspects of Tools for Developing Scientific Data Management Plans

Data Science Journal
Data Management Plans (DMPs) are relevant documents that help ensure data integrity and transparency. In this study, we analyze tools for constructing DMPs based on the fundamental aspects needed for proper scientific data management.
Fabiano Couto Corrêa Silva, Sandra de Albuquerque Siebra, Laura Vilela Rodrigues Rezende, Alexandre Faria de Oliveira, Denise Oliveira de Araújo   +4 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Data management plans

, 2019
These are slides the slides of the presentation on Data Management Plans given by Madeleine de Smaele and Yasemin Türkyilmaz-van der Velden during the 2nd ARMA-NL Meeting on 17 June 2019.
Madeleine de Smaele (6850892), Yasemin Turkyilmaz-van der Velden (6501053), Yasemin Turkyilmaz-van der Velden, Madeleine de Smaele   +3 more
core   +1 more source

Assessing Quality Variations in Early Career Researchers’ Data Management Plans

International Journal of Digital Curation
This paper aims to better understand early career researchers’ (ECRs’) research data management (RDM) competencies by assessing the contents and quality of  data management plans (DMPs) developed during a multi-stakeholder RDM course.
Jukka Rantasaari
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Data Management Plans [PDF]

, 2017
Presentation to researchers at a Workshop on Data Management Plans, Merensky Library, University of Pretoria, Pretoria, South Africa, 25 August 2017.The presentation gives a description of what a data management plan is, and why it is necessary to create
Van Wyk, Johann, Van der Walt, Isak
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

madmpy: A Python library for creating and validating Data Management Plans

SoftwareX
Data Management Plans (DMPs) are documents that describe the data used and produced during the course of research projects. Machine-actionable DMPs (maDMPs) are plans written in computer-readable formats.
Alberto Ballesteros-Rodríguez, Miguel-Ángel Sicilia, Elena García-Barriocanal   +2 more
doaj   +1 more source