Results 101 to 110 of about 32,390,911 (232)

A research data management (RDM) community for ELIXIR [version 2; peer review: 2 approved]

F1000Research
Research data management (RDM) is central to the implementation of the FAIR (Findable Accessible, Interoperable, Reusable) and Open Science principles.
Clare Garrard, Teresa D’Altri, Xenia Perez-Sitja, Minna Ahokas, Niclas Jareborg, Flavio Licciulli, Ivan Mičetić, Nils-Christian Lübke, Helena Schnitzer, Daniel Wibberg, Yvonne Kallberg, Flora D'Anna, Patricia M. Palagi, Mijke Jetten, Korbinian Bösl, Wei Gu, Munazah Andrabi, Katharina F. Heil, Susanna-Assunta Sansone, Ana M. P. Melo, Jiri Vondrasek, Daniel Faria, Ulrike Wittig, Anastasis Oulas, Jorge Oliveira, Pinar Alper, Robert Andrews, Siiri Fuchs, Celia van Gelder, Thanasis Vergoulis, Brane Leskošek, Krzysztof Poterlowicz, Patrick Ruch, Nazeefa Fatima   +33 more
doaj   +1 more source

Representation of Sickle Cell Disease Patients in Pediatric and Adult Care: What We Discovered Using Informatics for Integrating Biology and the Bedside (i2b2) Data

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Transitioning from pediatric to adult care is a high‐risk period for individuals with sickle cell disease (SCD). An initial observation at one academic medical center suggested a sex‐based disparity in clinic populations, prompting a national investigation.
Laurie J. Duckworth, Kholod Alhassan, Ada De La Osa, John Stephen, Yue Yao, Diana J. Wilkie   +5 more
wiley   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

NIH Data Sharing Requirements 101 [PDF]

, 2015
Presentation slides on National Institutes of Health data sharing policies for digital scientific data, data management plans, and ...
Data Management Services, Zach S. Henderson Library
core  

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida, Kengo Asahina, Keiichi Osano, Natsumi Saegusa, Kohei Yamamura, Kie Ohkoshi, Miho Shikata, Toshihisa Ishii, Makiko Konishi, Kazuya Takahashi, Kohei Uchimura, Ayumu Nakashima   +11 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Data Management Plan I

Data Management Plan I is a public version of a deliverable of the Horizon Europe project PEACE. The original deliverable was delivered to the granting authority, Clean Hydrogen Partnership, in August 2023.   The PEACE DMP is guided by the EU Open Science policy and Horizon Europe Data Management Plan obligations.
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Gathering Feedback from Early-Career Faculty: Speaking with and Surveying Agricultural Faculty Members about Research Data

Journal of eScience Librarianship, 2013
In spring 2013, the Life Sciences Data Services Librarian at the University of Illinois at Urbana-Champaign gave a data management presentation to early-career, agricultural faculty members participating in a selective program designed to help them ...
Sarah C. Williams
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source