Results 111 to 120 of about 1,926,704 (269)

Implementing and Learning from a Summer Research Data Management Training Program for Student Researchers

Partnership: The Canadian Journal of Library and Information Practice and Research
Background This study explores a library-led research data management (RDM) training program at a Canadian post-secondary institution that targeted students participating in summer research assistantships as well as their faculty supervisors.
Kevin B. Read, Sarah Rutley
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Essential Aspects of Tools for Developing Scientific Data Management Plans

Data Science Journal
Data Management Plans (DMPs) are relevant documents that help ensure data integrity and transparency. In this study, we analyze tools for constructing DMPs based on the fundamental aspects needed for proper scientific data management.
Fabiano Couto Corrêa Silva, Sandra de Albuquerque Siebra, Laura Vilela Rodrigues Rezende, Alexandre Faria de Oliveira, Denise Oliveira de Araújo   +4 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Assessing Quality Variations in Early Career Researchers’ Data Management Plans

International Journal of Digital Curation
This paper aims to better understand early career researchers’ (ECRs’) research data management (RDM) competencies by assessing the contents and quality of  data management plans (DMPs) developed during a multi-stakeholder RDM course.
Jukka Rantasaari
doaj   +1 more source

Changes in Manure Management in the Hog Sector [PDF]

In recent years, structural changes in the hog sector, including increasing farm size and regional shifts in production, have altered manure management practices. Over the same period, changes to the Clean Water Act, new state regulations, and increasing
Key, Nigel D., McBride, William D., Ribaudo, Marc   +2 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Sustainable forest management in Cameroon needs more than approved forest management plans

, 2015
One of the main objectives of the 1994 Cameroonian forestry law is to improve the management of production forests by including minimum safeguards for sustainability into compulsory forest management plans. As of 2007, about 3.5 million hectares (60%) of
Cerutti, Paolo, Nasi, Robert, Tacconi, Luca   +2 more
core  

A QUALITY IMPROVEMENT STUDY OF THE implimentation of the VERMONT NEWBORN PLAN OF SAFE CARE AMONG NURSING STAFF AT VERMONT HOSPITALS [PDF]

, 2019
PURPOSE: The purpose of this quality improvement needs assessment was to evaluate the implementation of the Vermont Newborn Plan of Safe Care (VNPSC) since its introduction 17 months ago. These plans were created in response to federal mandates to create
Buley, Annik
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source