Results 101 to 110 of about 30,805,646 (334)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Deep learning accelerated the discovery of multi‐principal element alloys with various strength‐toughness trade‐offs

Materials Genome Engineering Advances
Machine learning has significantly enhanced the efficiency of multi‐principal element alloys (MPEAs) development. Nonetheless, despite its potential, the rapid discovery of MPEAs with various strength‐toughness trade‐offs remains a largely unexplored ...
Chunhui Fan, Hong Luo, Qiancheng Zhao, Xuefei Wang, Hongxu Cheng, Yue Chang   +5 more
doaj   +1 more source

GAMMA_FLOW: Guided Analysis of Multi-label spectra by MAtrix Factorization for Lightweight Operational Workflows

SoftwareX
gamma_flow is an open-source Python package for real-time analysis of spectral data. It supports classification, denoising, decomposition, and outlier detection of both single- and multi-component spectra.
Viola Rädle, Tilman Hartwig, Benjamin Oesen, Emily Alice Kröger, Julius Vogt, Eike Gericke, Martin Baron   +6 more
doaj   +1 more source

Examined Lives: Informational Privacy and the Subject as Object [PDF]

, 2000
In the United States, proposals for informational privacy have proved enormously controversial. On a political level, such proposals threaten powerful data processing interests.
Cohen, Julie E.
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Fusion of multi source data for atmospheric corrosion evaluation using sensors and image recognition

npj Materials Degradation
s Detecting corrosion in Q235 steel is crucial for ensuring the safety and maintenance of industrial facilities. In this study, we present a novel approach that combines image recognition techniques with corrosion sensor data to improve both the accuracy
Weitong Wu, Di Xu, Liangan Liu, Bingqin Wang, Xuequn Cheng, Xin Zhang, Xiaogang Li   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Time Protection: the Missing OS Abstraction [PDF]

, 2018
Timing channels enable data leakage that threatens the security of computer systems, from cloud platforms to smartphones and browsers executing untrusted third-party code.
Acıiçmez Onur, Acıiçmez Onur, Bomberger Alan C., Boyd-Wickizer Silas, Bulck Jo Van, Doychev Goran, Ford Bryan, Gras Ben, Hughes-Hallet Deborah, İnci Mehmet Sinan, Kim Taesoo, Kocher Paul, Lipp Moritz, Liu Fangfei, Lynch William L., Noll Stefan, Percival Colin, van Schaik Stephan, Wu Zhenyu, Yarom Yuval, Yarom Yuval, Yarom Yuval, Zellweger Gerd   +22 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Translating proprietary protection setting data into standardized IEC 61850 format for protection setting validation [PDF]

, 2014
For smart grid development, one of the key expectations is that the data should be accessible to and readily interpreted by different applications. Presently, protection settings are represented using proprietary parameters and stored in various file ...
Blair, Steven Macpherson, Booth, Campbell, Catterson, Victoria, Dysko, Adam, Hong, Qiteng, Rahman, Tahasin   +5 more
core   +1 more source