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Proceedings of the ACM on Programming Languages, 2020 Data science is increasingly important and challenging. It requires computational tools and programming environments that handle big data and difficult computations, while supporting creative, high-quality analysis. The R language and related software play a major role in computing for data science.
openaire +4 more sources
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
The UMAP Journal 36 (2015) 285-292, 2016 Statistics is running the risk of appearing irrelevant to today's undergraduate students. Today's undergraduate students are familiar with data science projects and they judge statistics against what they have seen. Statistics, especially at the introductory level, should take inspiration from data science so that the discipline is not seen as somehow ...
arxiv
Phenomenology of Philosophy of Science: OPERA data [PDF]
, 2012 I observe that, as the physics side of the OPERA-anomaly story is apparently unfolding, there can still be motivation for philosophy of science to analyze the six months of madness physicists spent chasing the dream of a new fundamental-physics ...
Amelino-Camelia, Giovanni
core +1 more source
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
Shock tests on Mariner Venus 67 prototype data automation subsystems to evaluate multilayer laminate ...
core +1 more source
A Primer on Causality in Data Science [PDF]
, 2019 Many questions in Data Science are fundamentally causal in that our objective is to learn the effect of some exposure, randomized or not, on an outcome interest.
Balzer, Laura B., Saddiki, Hachem
core +1 more source
FEBS Letters, EarlyView.We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin +2 more
wiley +1 more source
Data Visualization Tools for Science and Math [PDF]
, 1999 As the computers available in schools become more powerful, more and more exciting tools are available to science and math students and teachers. Visualization tools, such as image processing, geographic information systems, modeling, and simulation ...
Kolvoord, B.
core +1 more source
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, EarlyView.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source