Results 71 to 80 of about 2,990,008 (372)

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

A Novel Method for Solving Multiobjective Linear Programming Problems with Triangular Neutrosophic Numbers

Journal of Mathematics, 2021
In the field of operation research, linear programming (LP) is the most utilized apparatus for genuine application in various scales. In our genuine circumstances, the manager/decision-makers (DM) face problems to get the optimal solutions and it even ...
Qing Wang, Yi Huang, Shiming Kong, Xinqiang Ma, Youyuan Liu, S. K. Das, S. A. Edalatpanah   +6 more
doaj   +1 more source

Multidimensional data visualization [PDF]

Behavior Research Methods, Instruments, & Computers, 2002
Historically, data visualization has been limited primarily to two dimensions (e.g., histograms or scatter plots). Available software packages (e.g., Data Desk 6.1, MatLab 6.1, SAS-JMP 4.04, SPSS 10.0) are capable of producing three-dimensional scatter plots with (varying degrees of) user interactivity.
Matthew J. Pastizzo, Robert F. Erbacher, Laurie Beth Feldman   +2 more
openaire   +3 more sources

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

FEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti, Sebastian Obermaier, Dirk J. Slotboom, Bert Poolman   +3 more
wiley   +1 more source

Visual attention information can be traced on cortical response but not on the retina: evidence from electrophysiological mouse data using natural images as stimuli [PDF]

arXiv, 2023
Visual attention forms the basis of understanding the visual world. In this work we follow a computational approach to investigate the biological basis of visual attention. We analyze retinal and cortical electrophysiological data from mouse. Visual Stimuli are Natural Images depicting real world scenes.
arxiv  

What May Visualization Processes Optimize?

, 2015
In this paper, we present an abstract model of visualization and inference processes and describe an information-theoretic measure for optimizing such processes.
Chen, Min, Golan, Amos
core   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

Molecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens, Anouk Mentink, Frank A. W. Coumans, Eshwari Dathathri, Khrystany T. Isebia, Jaco Kraan, Ronald de Wit, John W. M. Martens, Leon W. M. M. Terstappen   +8 more
wiley   +1 more source

Visualizing Gene Clusters using Neighborhood Graphs in R [PDF]

, 2008
The visualization of cluster solutions in gene expression data analysis gives practitioners an understanding of the cluster structure of their data and makes it easier to interpret the cluster results.
Leisch, Friedrich, Scharl, Theresa
core   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

A Review of Three-Dimensional Medical Image Visualization

Health Data Science, 2022
Importance. Medical images are essential for modern medicine and an important research subject in visualization. However, medical experts are often not aware of the many advanced three-dimensional (3D) medical image visualization techniques that could ...
Liang Zhou, Mengjie Fan, Charles Hansen, Chris R. Johnson, Daniel Weiskopf   +4 more
doaj   +1 more source