Results 91 to 100 of about 2,604,170 (298)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures [PDF]

, 2019
Antonina Andreeva, Eugene Kulesha, Julian Gough, Alexey G. Murzin   +3 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

ThePREDICTSdatabase: a global database of how local terrestrial biodiversity responds to human impacts [PDF]

, 2014
Lawrence N. Hudson, Tim Newbold, Sara Contu, Samantha L. L. Hill, Igor Lysenko, Adriana De Palma, Helen R. P. Phillips, Rebecca A. Senior, Dominic J. Bennett, Hollie Booth, Argyrios Choimes, David Correia, Julie Day, Susy Echeverría‐Londoño, Morgan Garon, Michelle L. K. Harrison, Daniel J. Ingram, Martin Jung, Victoria Kemp, Lucinda Kirkpatrick, Callum D. Martin, Yuan Pan, Hannah J. White, Job Aben, Stefan Abrahamczyk, Gilbert B. Adum, Virginia Aguilar‐Barquero, Marcelo A. Aizen, Marc Ancrenaz, Enrique Arbeláez‐Cortés, Inge Armbrecht, Badrul Azhar, Adrián B. Azpiroz, Lander Baeten, Andràs Báldí, John E. Banks, Jos Barlow, Péter Batáry, Adam J. Bates, Erin M. Bayne, Pedro Beja, Åke Berg, Nicholas Berry, Jake E. Bicknell, Jochen H. Bihn, Katrin Böhning‐Gaese, Teun Boekhout, Céline Boutin, Jérémy Bouyer, Francis Q. Brearley, Isabel Brito, Jörg Brunet, Grzegorz Buczkowski, Erika Buscardo, Jimmy Cabra‐García, María Calviño‐Cancela, Sydney A. Cameron, Eliana M. Cancello, Tiago F. Carrijo, Anelena Lima de Carvalho, Helena Castro, Alejandro Antonio Castro-Luna, Rolando Cerda, Alexis Cerezo, Matthieu Chauvat, Frank M. Clarke, Daniel F. R. Cleary, Stuart Connop, Biagio D’Aniello, Pedro Giovâni da Silva, Ben Darvill, Jens Dauber, Alain Déjean, Tim Diekötter, Yamileth Domínguez‐Haydar, Carsten F. Dormann, Bertrand Dumont, Simon G. Dures, Mats Dynesius, Lars Edenius, Zoltán Elek, Martin H. Entling, Nina Farwig, Tom M. Fayle, Antonio Felicioli, Annika M. Felton, Gentile Francesco Ficetola, Bruno K. C. Filgueiras, Steven J. Fonte, Lauchlan H. Fraser, Daisuke Fukuda, Dario Furlani, Jörg U. Ganzhorn, Jenni G. Garden, Carla Gheler‐Costa, Paolo Giordani, Simonetta Giordano, Marco Silva Gottschalk, Dave Goulson, Aaron D. Gove   +99 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

PHI-base: a new interface and further additions for the multi-species pathogen–host interactions database [PDF]

, 2016
Martin Urban, Alayne Cuzick, Kim Rutherford, Alistair G. Irvine, Helder Pedro, Rashmi Pant, Vidyendra Sadanadan, Lokanath Khamari, Santoshkumar Billal, Sagar Mohanty, K. E. Hammond‐Kosack   +10 more
openalex   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

RD-Connect: An Integrated Platform Connecting Databases, Registries, Biobanks and Clinical Bioinformatics for Rare Disease Research [PDF]

, 2014
Rachel Thompson, Louise Johnston, Domenica Taruscio, Lucía Monaco, Christophe Béroud, Marta Gut, Mats Hansson, Peter-Bram Ac 't Hoen, George P. Patrinos, Hugh Dawkins, Monica Ensini, Kurt Zatloukal, David Koubi, Emma Heslop, Justin Paschall, Manuel Posada de la Paz, Peter N. Robinson, Kate Bushby, Hanns Lochmüller   +18 more
openalex   +1 more source

Development of a standard database of reference sites for validating global burned area products [PDF]

, 2020
Magí Franquesa, Melanie K. Vanderhoof, Dimitris Stavrakoudis, Ioannis Z. Gitas, Ekhi Roteta, Marc Padilla, Emilio Chuvieco   +6 more
openalex   +1 more source