Results 61 to 70 of about 16,804,247 (357)

CockroachDB: The Resilient Geo-Distributed SQL Database

open access: yesSIGMOD Conference, 2020
We live in an increasingly interconnected world, with many organizations operating across countries or even continents. To serve their global user base, organizations are replacing their legacy DBMSs with cloud-based systems capable of scaling OLTP ...
Rebecca Taft   +16 more
semanticscholar   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Incremental Database Design using UML-B and Event-B [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2018
Correct operation of many critical systems is dependent on the data consistency and integrity properties of underlying databases. Therefore, a verifiable and rigorous database design process is highly desirable.
Ahmed Al-Brashdi   +2 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Physical design of temporal databases [PDF]

open access: yes, 1988
The primary focus of research into temporal databases has been on logical data modeling. Yet, the feasibility of implementing such databases depends as much on the development of retrieval and storage structures that are suited to the unique nature of temporal data.
Gunadhi, H, Segev, A
openaire   +4 more sources

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

Perspectives on the Role of Business Rules in Database Design [PDF]

open access: yesDatabase Systems Journal, 2012
Business rules are at the foundation of every information system as they drive and offer guidelines for managing and conducting all activities within an organizations.
Anca Ioana ANDREESCU, Marinela MIRCEA
doaj  

Generic dependencies and database design

open access: yesComputers & Mathematics with Applications, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kannan Nambiar, Vinod Kannoth
openaire   +2 more sources

Using Links to prototype a Database Wiki [PDF]

open access: yes, 2011
Both relational databases and wikis have strengths that make them attractive for use in collaborative applications. In the last decade, database-backed Web applications have been used extensively to develop valuable shared biological references called ...
Cheney, James   +2 more
core   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

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