Results 111 to 120 of about 5,268,956 (336)

Building a livestock genetic and genomic information knowledgebase through integrative developments of Animal QTLdb and CorrDB

Nucleic Acids Res., 2018
Successful development of biological databases requires accommodation of the burgeoning amounts of data from high-throughput genomics pipelines. As the volume of curated data in Animal QTLdb (https://www.animalgenome.org/QTLdb) increases exponentially ...
Zhi-Liang Hu, Carissa A. Park, J. Reecy
semanticscholar   +1 more source

IndiGenomes: a comprehensive resource of genetic variants from over 1000 Indian genomes

Nucleic Acids Research, 2020
With the advent of next-generation sequencing, large-scale initiatives for mining whole genomes and exomes have been employed to better understand global or population-level genetic architecture.
Abhinav R Jain, R. Bhoyar, Kavita Pandhare, A. Mishra, D. Sharma, M. Imran, V. Senthivel, M. Divakar, M. Rophina, B. Jolly, Arushi Batra, Sumit Sharma, Sanjay Siwach, A. Jadhao, N. V. Palande, G. N. Jha, Nishat Ashrafi, P. Mishra, Vidhya A. K., Suman Jain, D. Dash, N. S. Kumar, Andrew Vanlallawma, Ranjan Jyoti Sarma, Lalchhandama Chhakchhuak, S. Kalyanaraman, Radha Mahadevan, Sunitha Kandasamy, Pabitha B. M., Raskin Erusan Rajagopal, Ezhil Ramya J., N. P., Anjali Bajaj, V. Gupta, Samatha Mathew, S. Goswami, Mohit Mangla, S. Prakash, Kandarp Joshi, Meyakumla, S. S., Devarshi Gajjar, R. Soraisham, R. Yadav, Yumnam Silla Devi, Aayush Gupta, M. Mukerji, S. Ramalingam, Binukumar B. K., V. Scaria, S. Sivasubbu   +50 more
semanticscholar   +1 more source

Caenorhabditis nomenclature [PDF]

, 2018
Genetic nomenclature allows the genetic features of an organism to be structured and described in a uniform and systematicway. Genetic features, including genes, variations (both natural and induced), and gene products, are assigned descriptorsthat ...
Daul, Aric, Schedl, Tim, Tuli, Mary Ann
core   +2 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Conservation of genetic resources in the Cucurbitaceae family in Bulgaria

Растениевъдни науки, 2013
A rich collection of 2014 local and introduced accessions from Cucurbitaceae family is supported at the Institute of Plant Genetic Resources in Sadovo. Local forms are collected from different regions in North and South Bulgaria.
Stefan Neykov, Lilia Krasteva, Nikolaya Velcheva, Dochka Dimova   +3 more
doaj  

The promise of human genetic databases [PDF]

BMJ, 2001
Genetic databases are now helping elucidate gene function, estimate the prevalence of genes in populations, differentiate among subtypes of diseases, trace how genes may predispose to or protect against illnesses, and improve medical intervention. They achieve this by bringing together several streams of data about individuals: molecular genetic data ...
openaire   +2 more sources

C6orf10 low-frequency and rare variants in italian multiple sclerosis patients [PDF]

, 2019
In light of the complex nature of multiple sclerosis (MS) and the recently estimated contribution of low-frequency variants into disease, decoding its genetic risk components requires novel variant prioritization strategies.
Balestra, Dario, Benazzo, Andrea, Bernardi, Francesco, Bovolenta, Matteo, Bozzini, Nicolò, Gemmati, Donato, Guidi, Irene, Laino, Lorenza Anna, Lunghi, Barbara, Marchetti, Giovanna, Menegatti, Erica, Meneghetti, Silvia, Salvi, Fabrizio, Scapoli, Chiara, Straudi, Sofia, Zamboni, Paolo, Ziliotto, Nicole   +16 more
core   +2 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Identification of genetic markers associated with cisplatin-induced toxicity using public genomic databases

Clinical Medicine
Introduction: Cisplatin is a widely used chemotherapeutic agent for treating various malignancies. However, its clinical utility is often restricted by toxicities, such as nephrotoxicity, neurotoxicity and ototoxicity.1 Identifying genetic factors ...
Suvam Banerjee
doaj   +1 more source

New Scientific and Technological Developments of Relevance to the Fifth Review Conference [PDF]

, 2001
Ye
Pearson, Graham S.
core