Results 91 to 100 of about 453,721 (346)

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Diagnostic potential of cell-free fetal nucleic acids in predicting pregnancy complications: A systematic review and meta-analysis on trisomy, pre-eclampsia, and gestational diabetes

International Journal of Reproductive BioMedicine
Background: Recent studies reveal an association between increased cell-free fetal (cff) nucleic acid in maternal blood and pregnancy challenges like loss, pre-eclampsia, growth restriction, and preterm labor.
Jiut Ram Keshari, Pritam Prakash, Seema Rani Sinha, Prem Prakash, Kirti Rani, Tarique Aziz, Shaily Shilpa   +6 more
doaj   +1 more source

A mouse variable gene fragment binds to DNA independently of the BCR context: a possible role for immature B-cell repertoire establishment. [PDF]

PLoS ONE, 2013
B-cell maturation occurs in several steps and requires constant stimulus for its continuing development. From the emergence of the pre-B-cell receptor, signal transduction stimulates and supports B-cell development.
Andrea Queiroz Maranhão, Maria Beatriz Walter Costa, Leonardo Guedes, Pedro Manoel Moraes-Vieira, Tainá Raiol, Marcelo Macedo Brigido   +5 more
doaj   +1 more source

Identification of MTHFD2 as a prognostic biomarker and ferroptosis regulator in triple-negative breast cancer

Frontiers in Oncology, 2023
BackgroundMethylenetetrahydrofolate dehydrogenase 2 (MTHFD2) is a mitochondrial bifunctional enzyme encoded in the nucleus. It plays a significant role in the regulation of glucose, nucleic acid, and folate metabolism, and maintains redox balance in the ...
Hao Zhang, Shuangli Zhu, Haiting Zhou, Rui Li, Xiaohui Xia, Huihua Xiong   +5 more
doaj   +1 more source

The Relationship between the UniProt Knowledgebase (UniProtKB) and the IntAct Molecular Interaction Databases [PDF]

, 2009
IntAct provides a freely available, open source database system and analysis tools for protein interaction data. All interactions are derived from literature curation or direct user submission and all experimental information relating to binary protein ...
Yasmin Alam-Faruque
core   +2 more sources

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

A systematic review of brain imaging findings in neurological infection with Japanese encephalitis virus compared with Dengue virus

International Journal of Infectious Diseases, 2022
Objectives: Japanese encephalitis virus (JEV) and dengue virus (DENV) represent important causes of encephalitis in Asia. Brain imaging may provide diagnostic clues about the etiology of infectious encephalitis.
Thomas Pichl, Catherine J Wedderburn, Chandrashekar Hoskote, Lance Turtle, Tehmina Bharucha   +4 more
doaj   +1 more source

The 2015 Nucleic Acids Research Database Issue and Molecular Biology Database Collection [PDF]

Nucleic Acids Research, 2015
Abstract The 2015 Nucleic Acids Research Database Issue contains 172 papers that include descriptions of 56 new molecular biology databases, and updates on 115 databases whose descriptions have been previously published in NAR or other journals.
Michael Y. Galperin, Daniel J. Rigden, Xosé M. Fernández-Suárez   +2 more
openaire   +2 more sources

Exploring the Potential of Zero‐Dimensional Carbon Nanomaterials in Photoluminescent, Electrochemiluminescent and Electrochemical Sensors

Advanced Materials Interfaces, EarlyView.
Zero‐dimensional carbon nanomaterials are presented as multifunctional platforms linking structure, property, and sensing performance. Surface engineering and heteroatom doping modulate electron‐transfer and luminescent behavior, enabling electrochemical, photoluminescent, and electrochemiluminescent detection. Fundamental design principles, analytical
Gustavo Martins, Jeferson Luiz Gogola, Ava Gevaerd, Cristiane Kalinke, Paulo Roberto de Oliveira, Fabio Roberto Caetano, Bruno Campos Janegitz, Márcio Fernando Bergamini, Luiz Humberto Marcolino‐Junior   +8 more
wiley   +1 more source

Current Updates on Molecular Diagnostic Assays Used for Detection of Candida auris: A Systematic Review

Diagnostics
Background/Objectives: Candida auris is an emerging multidrug-resistant pathogen with the potential to cause invasive fungal infections and healthcare-associated outbreaks.
River Chun-Wai Wong, Alfred Lok-Hang Lee, Ingrid Yu-Ying Cheung, Viola Chi-Ying Chow, Margaret Ip, Christopher Koon-Chi Lai   +5 more
doaj   +1 more source