Results 191 to 200 of about 92,055 (268)

Improvement of a phylogenetic footprinting method for transcription factor binding sites recognition based on the use of bootstrap trials for the analysis of large bacterial genomic data. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Mukhin AM, Khlebodarova TM, Oshchepkov DY.   +2 more
europepmc   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source

Association between nucleic acid COVID-19 vaccines and acute myocardial infarction in adults: a systematic review. [PDF]

Front Cardiovasc Med
Castellanos-Hernández DI, Mayoral-Chávez MA, Matias-Cervantes CA, Alpuche J.   +3 more
europepmc   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Protein structure-informed bacteriophage genome annotation with Phold. [PDF]

Nucleic Acids Res
Bouras G, Grigson SR, Mirdita M, Heinzinger M, Papudeshi B, Mallawaarachchi V, Green R, Kim RS, Mihalia V, Psaltis AJ, Wormald PJ, Vreugde S, Steinegger M, Edwards RA.   +13 more
europepmc   +1 more source

Revisiting Burn Wound Infections: A Comprehensive Review on the Dual Potential of Phages and Probiotics Against Acinetobacter baumannii

Journal of Clinical Laboratory Analysis, EarlyView.
Effect Probiotics on immune system modulation and wound Healing. ABSTRACT Introduction Burn wound infections caused by Acinetobacter baumannii remain a critical clinical challenge due to its extensive multidrug resistance, particularly against carbapenems.
Zeinab Fagheei Aghmiyuni, Shahrzad Aliniay Sharafshadehi, Roghayeh Afifirad, Elnaz Bafandeh, Maryam Mokhtaryan, Roya Ghanavati, Atieh Darbandi   +6 more
wiley   +1 more source

Plant virome analysis by high-throughput sequencing: concepts and approaches. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Belkina DD, Vinogradova SV.
europepmc   +1 more source

Diagnostic Performance of Direct PCR Assay for Candida auris Detection: A Comparison of Liquid Amies Transport Medium and Fungal Enrichment Broth

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluated a direct PCR assay for rapid Candida auris screening from skin swabs using two transport media. The direct PCR assay demonstrated high sensitivity (92.0%–96.0%) and rapid turnaround time (~3 h). Liquid Amies medium showed a more favorable specificity profile, supporting its practical utility for screening.
Jung‐ah Kim, Yu Kyung Jeon, Eun Jeong Won, Heungsup Sung, Mi‐Na Kim   +4 more
wiley   +1 more source

Setting higher standards for reports of microbial species in human cancers. [PDF]

Nat Cancer
Salzberg SL, Chia M, Tay A, de Miranda NFCC, Smit V, Wesseling J, Irizarry R, Marshall B, Willerslev E, Neefjes J, Nagarajan N.   +10 more
europepmc   +1 more source

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

Journal of Raman Spectroscopy, EarlyView.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira, Adriano Moraes da Silva, Marcos Tadeu T. Pacheco, Landulfo Silveira Jr.   +3 more
wiley   +1 more source