Results 171 to 180 of about 92,055 (268)

DNA Methylation and Transcriptomic Profiles of Wilms Tumour Reveal New Deregulated Genes and Epigenetic Processes Relevant for Tumour Stratification and Management

International Journal of Cancer, EarlyView.
ABSTRACT Wilms Tumour (WT), the most common kidney cancer in children, presents features of altered kidney development and frequently exhibits molecular alterations at the 11p15.5 imprinted locus, affecting the IGF2 and H19 genes, which contribute to tumour growth and predisposition.
Abu Saadat, Francesco Cecere, Federica Rossetti, Laura Pignata, Emilia D'Angelo, Carlo Giaccari, Gaetano Verde, Paola Quarello, Franca Fagioli, Josep Roma, Manel Esteller, Enrique de Álava, Flavia Cerrato, Andrea Riccio, Angela Sparago   +14 more
wiley   +1 more source

Basic Microbiome Analysis: Analytical Steps from Sampling to Sequencing. [PDF]

Microorganisms
Ece G, Aktaş A, Koyuncu Özyurt Ö, Demirbakan H, Alışkan HE, Sağlık İ, Zorbozan O, Çetin Duran A, Uğur AR, Öcal D, Uzunoğlu E, Kaya E, Mutlu Sarıgüzel F, Bayındır F, Yetkin G, Altındiş M, Yenice Aktaş S, Kula Atik T.   +17 more
europepmc   +1 more source

Minimally Invasive Sampling for Molecular Profiling of Lymph Nodes Using a Modified Acupuncture Needle

iMetaMed, EarlyView.
Schematic illustration of the preparation of His@PDA@Needle, a modified acupuncture needle designed for minimally invasive sampling of lymph node‐derived DNA for molecular profiling. ABSTRACT Current clinical liquid biopsy approaches predominantly rely on blood‐derived biomarkers, which are often limited in sensitivity.
Baiping Cui, Mingyu Li, Pingzhu Zhou, Lihfeng Cheow, Hailong Ma, Dongdong Liu   +5 more
wiley   +1 more source

Comprehensive evaluation of artificial intelligence-empowered approaches for protein-aptamer complex prediction. [PDF]

Brief Bioinform
Zhao J, Tram K, Yan H, Li Y.
europepmc   +1 more source

Wekemo Bioincloud 2026: An AI‐enabled platform for standardized multi‐omics data analyses

iMeta, EarlyView.
An AI‐powered multi‐omics cloud platform integrating 41 standardized workflows, 126 visualization tools, and full‐lifecycle research intelligence to enable accessible, reproducible, and end‐to‐end integrative multi‐omics analysis. Abstract The rapid expansion of multi‐omics data has created an increasing demand for accessible and reproducible platforms
Yunyun Gao, Guoxing Zhang, Chengrui Wang, Hao Xu, Zhanhui Yu, Shunyao Jiang, Yong‐Xin Liu   +6 more
wiley   +1 more source

Enabling global-scale nucleic acid repositories through versatile, scalable biochemical selection from room-temperature archives. [PDF]

Nat Commun
Berleant JD, Banal JL, Rao DK, Bathe M.
europepmc   +1 more source

Hyperoside alleviates endometrial stromal cell senescence in unexplained recurrent spontaneous abortion via DHX9‐mediated R‐loop resolution

iMeta, EarlyView.
This study suggests that the food‐derived flavonoid hyperoside may act as a natural DExH‐box helicase 9 (DHX9) modulator, directly targeting Thr419 of DHX9 to help resolve pathological R‐loop accumulation. Consequently, it suppresses cyclic GMP‐AMP synthase‐stimulator of interferon genes (cGAS‐STING)‐driven endometrial stromal senescence and restores ...
Yuepeng Jiang, Hongli Zhao, Xinyi Ding, Haoling Zhang, Yadong Guo, Yiming Ma, Lingyi Cai, Qingnan Fan, Ruisi Peng, Fuyuan Yang, Doblin Sandai, Xianling Cao, Jiali Yao, Wenyi Wang, Zhiheng Lin, Wangzheqi Zhang, Jialin He, Aihua Zhang, Xiaoxuan Zhao   +18 more
wiley   +1 more source

Microbial decomposer diversity and metabolic function during the decomposition of brine shrimp carcasses in a saline lake. [PDF]

Microbiome
Gao L, Fang BZ, Yang J, Lian ZH, Chen Y, Mohamad OAA, Xu QY, Liu YH, Wu D, Yuan Y, Abdugheni R, Li MM, Wang P, Ortúzar M, Li XY, Huang JR, Liu L, Jiang HC, Shu W, Hedlund BP, Li WJ, Jiao JY.   +21 more
europepmc   +1 more source

The plant microbiome: From ecological foundations to precision microbial engineering for sustainable agriculture

iMeta, EarlyView.
From ecological principles to precision engineering of plant microbiomes for sustainable agriculture. The plant holobiont integrates diverse microbial niches (including rhizosphere, endosphere, phyllosphere, seed, and aerial‐root mucilagesphere), host genetics (namely M genes), and host metabolites. Furthermore, molecular dialogues, including rhizobial
Mi Wei, Tengxiang Lian, Liying Chen, Lanxiang Wang, Junjie Ye, Xiaofang Yao, Shilong Duan, Ziyu Lu, Jinji Tu, Hongfu Li, Xin‐Yue Xu, Jie Zhou, Junliang He, Feiying Zhu, Paola Bonfante, Lam‐Son Phan Tran, Zhiqiang Pang, Xin Zhou, Zhihui Xu, Lin Zhang, Mengcen Wang, Xiaolin Wang, Chang‐Fu Tian, Yong‐Xin Liu, Kai Sun, Ertao Wang, Xianan Xie   +26 more
wiley   +1 more source

Discovery of a novel orthototivirus-like virus in patients with vulvovaginal candidiasis. [PDF]

Front Cell Infect Microbiol
Dai Z, Lu Q, Sun M, Chen H, Jiang Y, Yu T, Wang Z, Wang Y, Zhu R.   +8 more
europepmc   +1 more source