Results 281 to 290 of about 453,721 (346)

Polygenic risk score and prostate specific antigen predict death from prostate cancer in men with intermediate aggressive cancer

International Journal of Cancer, EarlyView.
What's New? Using 21 SNPs, two novel PRS were constructed and used to develop two new machine‐learning classifiers, one for the detection of prostate cancer and the other for the prediction of its aggressiveness and subsequent mortality. The classifier for disease detection is built using the PRS as the sole feature, whereas the one for disease ...
Leandro Rodrigues Santiago, Efthymios Ladoukakis, Dorota Scibior‐Bentkowska, Belinda Nedjai   +3 more
wiley   +1 more source

Tools and approaches to study the human gut virome: from the bench to bioinformatics. [PDF]

mSystems
Anne Hallowell H, Malogan J, Suez J.
europepmc   +1 more source

Nationwide Study on the Cervical Cancer Screening Pathway in Estonia

International Journal of Cancer, EarlyView.
Cervical cancer remains a significant burden despite being preventable, largely due to inadequate screening participation and poor follow‐up of high‐risk women. Here, the authors investigated follow‐up rates among women who tested positive for high‐risk human papillomavirus (hr‐HPV) infection in primary screening in Estonia. Data show that more than 57
Aleksandra Šavrova, Helen Jakoby, Anna Tisler, Kaire Innos, Ülo Maiväli, Jana Jaal, Anneli Uusküla   +6 more
wiley   +1 more source

CD-CODE 2.0: an enhanced condensate knowledgebase integrating pathobiology, condensate modulating drugs, and host-pathogen interactions. [PDF]

Nucleic Acids Res
Kuznetsova K, Scheremetjew M, Yin J, Moon H, Vargas DA, Hadarovich A, Lewis N, Hoege C, Chow CFW, Kuster D, Nijssen J, Hernandez-Armendariz A, Savage JC, Wei Y, Zedlitz S, Singh HR, Ghosh S, Kemraj AP, Hersemann L, Hyman AA, Mitrea DM, Toth-Petroczy A.   +21 more
europepmc   +1 more source

bacNeo: A Computational Toolkit for Identifying Bacteria‐Derived Neoantigens in Human Cancers

iMetaMed, EarlyView.
We present bacterial neoantigen (bacNeo), a multi‐omics‐based computational software to classify bacterial components (BACC), type bacteria‐bound HLA alleles (BACH), and prioritize bacterial peptides as neoantigens (BACP). Bacterial neoantigen potential is quantified by score for peptide antigenicity recognition & kinetics (SPARK), enabling ...
Yunzhe Wang, Li Yuan, Katie W. Gu, Xiangdong Cheng, Bo Wen, Zhao Zhang   +5 more
wiley   +1 more source

Viromic profiling of amniotic fluid reveals distinct viral communities associated with maternal health status. [PDF]

BMC Pregnancy Childbirth
Wang H, Fu Y, Xu H, Song X, Huang S, Chen Y, Xu J, Li W, Zhang J, Wu P, Shen Q, Yang S, Wang X, Liu Y, Ji L, Li Y, Yang H, Tang J, Zhou C, Zhang W.   +19 more
europepmc   +1 more source

Hybrid deep learning with protein language models and dual-path architecture for predicting IDP functions. [PDF]

Brief Bioinform
Liang J, Luo Y, Su B, Peng Z.
europepmc   +1 more source

FireProtDB 2.0: large-scale manually curated database of the protein stability data. [PDF]

Nucleic Acids Res
Musil M, Borko S, Planas-Iglesias J, Lacko D, Rosinska M, Kabourek P, Martins LO, Tataruch M, Damborsky J, Mazurenko S, Bednar D.   +10 more
europepmc   +1 more source

Nucleic acid-induced chemokine expression in keratinocytes: Implications for skin inflammation. [PDF]

PLoS One
Danis J, Kelemen E, Balogh F, Szabó K, Fodor GH, Ádám É, Széll M.   +6 more
europepmc   +1 more source

Study on the correlation between molecular characteristics of SARS-CoV-2 and its epidemiology and clinical manifestations in Lu'an city. [PDF]

World J Virol
Chang HW, Yang W, Yu L, Gao DW, Zhang F, Chen ZC, Chen BL, Zhang LM, Zhu R, Zhang Q, Li ZY, Rao JG.   +11 more
europepmc   +1 more source