Results 271 to 280 of about 453,721 (346)

Enzymatic Prenylation of Proteins and Peptides: From Cysteine S‐Prenylation to Tryptophan‐Selective Biocatalysis

Chemistry – A European Journal, EarlyView.
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami, Hikari Ozawa, Sohei Ito   +2 more
wiley   +1 more source

MitoCommun: a database for decoding mitochondrial communication networks. [PDF]

BMC Genomics
Wu X, Chen D, Feng J, Bu X, Wu S, Qiao J.   +5 more
europepmc   +1 more source

Artificial intelligence in enzyme catalysis: Emerging trends and applications in biocatalyst engineering

The Canadian Journal of Chemical Engineering, EarlyView.
Schematic representation of artificial intelligence approaches in enzyme catalysis, integrating bibliometric analysis, emerging research trends, and machine learning tools for enzyme design, prediction, and industrial biocatalytic applications. Abstract This study systematically explores the applications of artificial intelligence (AI) in enzyme ...
Misael Bessa Sales, Francisco Izaias da Silva Aires, Paulo Gonçalves de Sousa Junior, Calebe Da Rocha Silva, Emanuel Lino Rodrigues, Maria Cristiane Martins de Souza, José C. S. dos Santos   +6 more
wiley   +1 more source

The IPD-IMGT/HLA database: recent developments in sequence submission. [PDF]

Nucleic Acids Res
Barker DJ, Natarajan RHL, Cooper MA, Hopper SJF, Yates AD, Parham P, Marsh SGE, Robinson J.   +7 more
europepmc   +1 more source

Perceived importance and didactic difficulty of chemistry education: Insights from Czech teachers

The Curriculum Journal, EarlyView.
Abstract This empirical study examines how chemistry teachers in lower and upper secondary schools in the Czech Republic evaluate the content of the chemistry curriculum, focussing on its perceived importance and didactic difficulty. Based on a quantitative survey (N = 146), the study provides insight into the pedagogical content knowledge of ...
Jitka Lorenzová, Blanka Jirkovská, Martin Čapek Adamec, Jan Havlík, Petr Holzhauser, Daniela Nováková, Karel Němejc   +6 more
wiley   +1 more source

Enzyme Engineering Database (EnzEngDB): a platform for sharing and interpreting sequence-function relationships across protein engineering campaigns. [PDF]

Nucleic Acids Res
Long Y, Abbasinejad F, Li FZ, Reinprecht P, Wittmann B, Kennemur JL, Carder H, Yang J, Lambert T, O'Meara R, Radtke L, Qin Z, Brinkmann-Chen S, Arnold F, Mora A.   +14 more
europepmc   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

NPCDR 2.0: the activity and structure landscape of natural product-based drug combination. [PDF]

Nucleic Acids Res
Gao Q, Yu X, Liu K, Zhu Z, Chen M, Zhao X, Liao Z, Xu L, Zhou Y, Zhu F, Sui X.   +10 more
europepmc   +1 more source

The Global Patent Landscape of Mushroom‐Derived Functional Foods: Current Status, Future Perspectives, and Artificial Intelligence–Driven Exploration

Food Safety and Health, EarlyView.
The global patent landscape of mushroom‐derived functional food was widely analyzed, and AI‐integrated approaches realizing cost‐effective and reliable exploration of functional foods derived from mushrooms were explored. ABSTRACT Global health concerns and the increasing demand for nourishment have collectively driven the rising demand for functional ...
Xihong Zhao, Linhuizi Xiang, Dongmei Liu, Shoucheng Qin, Yue Chen, Xueyan Sun   +5 more
wiley   +1 more source

Ribocentre-aptamer: an integrative, structure-focused database for RNA aptamers. [PDF]

Nucleic Acids Res
Lu Z, Sun H, Fu B, Ao Y, Wang J, Chen K, Luo Y, Li L, Qiu Z, Zhao J, Sun Y, Tan Z, Liu Q, Ren Y, Guo Z, Chen X, He Y, Zhao Y, Chen Y, Li M, Peng X, Huang B, Zhu S, Huang L, Miao Z.   +24 more
europepmc   +1 more source