Results 1 to 10 of about 666,912 (235)

Compressive genomics for protein databases [PDF]

open access: yesBioinformatics, 2013
Motivation: The exponential growth of protein sequence databases has increasingly made the fundamental question of searching for homologs a computational bottleneck.
A. Gallant   +24 more
core   +7 more sources

Protein sequence databases [PDF]

open access: yesCurrent Opinion in Chemical Biology, 2004
A variety of protein sequence databases exist, ranging from simple sequence repositories, which store data with little or no manual intervention in the creation of the records, to expertly curated universal databases that cover all species and in which the original sequence data are enhanced by the manual addition of further information in each ...
Apweiler, Rolf   +2 more
openaire   +7 more sources

Protein Databases on the Internet [PDF]

open access: yesCurrent Protocols in Molecular Biology, 2000
AbstractProtein databases have become a crucial part of modern biology. Huge amounts of data for protein structures, functions, and particularly sequences are being generated. Searching databases is often the first step in the study of a new protein.
Ying Xu, Dong Xu
openaire   +6 more sources

Closing the circle : current state and perspectives of circular RNA databases [PDF]

open access: yes, 2021
Circular RNAs (circRNAs) are covalently closed RNA molecules that have been linked to various diseases, including cancer. However, a precise function and working mechanism are lacking for the larger majority.
Vandesompele, Jo   +2 more
core   +1 more source

Databases for intrinsically disordered proteins [PDF]

open access: yesActa Crystallographica Section D Structural Biology, 2022
Intrinsically disordered regions (IDRs) lacking a fixed three-dimensional protein structure are widespread and play a central role in cell regulation. Only a small fraction of IDRs have been functionally characterized, with heterogeneous experimental evidence that is largely buried in the literature.
Piovesan, Damiano   +3 more
openaire   +2 more sources

The Halophile Protein Database [PDF]

open access: yesDatabase, 2014
Halophilic archaea/bacteria adapt to different salt concentration, namely extreme, moderate and low. These type of adaptations may occur as a result of modification of protein structure and other changes in different cell organelles. Thus proteins may play an important role in the adaptation of halophilic archaea/bacteria to saline conditions.
K. K. Chaturvedi   +6 more
openaire   +3 more sources

The Protein Mutant Database [PDF]

open access: yesNucleic Acids Research, 1999
Currently the protein mutant database (PMD) contains over 81 000 mutants, including artificial as well as natural mutants of various proteins extracted from about 10 000 articles. We recently developed a powerful viewing and retrieving system (http://pmd.ddbj.nig.ac.jp), which is integrated with the sequence and tertiary structure databases. The system
Motonori Ota   +2 more
openaire   +3 more sources

Moonlighting Proteins Database [PDF]

open access: yesBiophysical Journal, 2011
Moonlighting proteins comprise an interesting subset of multifunctional proteins in which the two functions are found in a single polypeptide chain. They do not include proteins that are multifunctional due to gene fusions, families of homologous proteins, splice variants, or promiscuous enzyme activities.
Mathew Mani, Constance J. Jeffery
openaire   +2 more sources

The Pfam Protein Families Database [PDF]

open access: yesNucleic Acids Research, 2000
Pfam is a large collection of protein families and domains. Over the past 2 years the number of families in Pfam has doubled and now stands at 6190 (version 10.0). Methodology improvements for searching the Pfam collection locally as well as via the web are described.
Bateman, Alex   +12 more
openaire   +7 more sources

MultitaskProtDB: a database of multitasking proteins [PDF]

open access: yesNucleic Acids Research, 2013
We have compiled MultitaskProtDB, available online at http://wallace.uab.es/multitask, to provide a repository where the many multitasking proteins found in the literature can be stored. Multitasking or moonlighting is the capability of some proteins to execute two or more biological functions. Usually, multitasking proteins are experimentally revealed
Hernández, Sergio   +7 more
openaire   +6 more sources

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