Results 11 to 20 of about 8,370,207 (250)

Protein sequence databases [PDF]

open access: yesCurrent Opinion in Chemical Biology, 2000
A variety of protein sequence databases exist, ranging from simple sequence repositories, which store data with little or no manual intervention in the creation of the records, to expertly curated universal databases that cover all species and in which the original sequence data are enhanced by the manual addition of further information in each ...
Apweiler, Rolf   +2 more
  +7 more sources

ProClass protein family database [PDF]

open access: yesNucleic Acids Research, 1999
ProClass is a protein family database that organizes non-redundant sequence entries into families defined collectively by PIR superfamilies and PROSITE patterns. By combining global similarities and functional motifs into a single classification scheme, ProClass helps to reveal domain and family relationships and classify multi-domain proteins.
C H, Wu, S, Shivakumar, H, Huang
openaire   +4 more sources

ProtGPT2 is a deep unsupervised language model for protein design

open access: yesNature Communications, 2022
Protein design aims to build novel proteins customized for specific purposes, thereby holding the potential to tackle many environmental and biomedical problems.
Noelia Ferruz   +2 more
semanticscholar   +1 more source

The Halophile Protein Database [PDF]

open access: yesDatabase, 2014
Halophilic archaea/bacteria adapt to different salt concentration, namely extreme, moderate and low. These type of adaptations may occur as a result of modification of protein structure and other changes in different cell organelles. Thus proteins may play an important role in the adaptation of halophilic archaea/bacteria to saline conditions.
Sharma, Naveen   +6 more
openaire   +2 more sources

Compressive genomics for protein databases [PDF]

open access: yes, 2013
Motivation: The exponential growth of protein sequence databases has increasingly made the fundamental question of searching for homologs a computational bottleneck.
A. Gallant   +24 more
core   +1 more source

The Protein Mutant Database [PDF]

open access: yesNucleic Acids Research, 1999
Currently the protein mutant database (PMD) contains over 81 000 mutants, including artificial as well as natural mutants of various proteins extracted from about 10 000 articles. We recently developed a powerful viewing and retrieving system (http://pmd.ddbj.nig.ac.jp), which is integrated with the sequence and tertiary structure databases. The system
T, Kawabata, M, Ota, K, Nishikawa
openaire   +2 more sources

Do protein–protein interaction databases identify moonlighting proteins? [PDF]

open access: yes, 2011
One of the most striking results of the human (and mammalian) genomes is the low number of protein-coding genes. To-date, the main molecular mechanism to increase the number of different protein isoforms and functions is alternative splicing. However,
Amitai   +31 more
core   +2 more sources

Structure-based protein function prediction using graph convolutional networks

open access: yesNature Communications, 2021
The rapid increase in the number of proteins in sequence databases and the diversity of their functions challenge computational approaches for automated function prediction. Here, we introduce DeepFRI, a Graph Convolutional Network for predicting protein
V. Gligorijević   +13 more
semanticscholar   +1 more source

Protein-protein interaction databases: keeping up with growing interactomes

open access: yesHuman Genomics, 2009
Over the past few years, the number of known protein-protein interactions has increased substantially. To make this information more readily available, a number of publicly available databases have set out to collect and store protein-protein interaction
Lehne Benjamin, Schlitt Thomas
doaj   +1 more source

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