Results 61 to 70 of about 53,590 (235)
Journal of Applied Toxicology, EarlyView.ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan +3 more
wiley +1 more source
Drug Delivery, 2017 A novel niosomal delivery system was designed and investigated for the targeted delivery of daunorubicin (DNR) against acute myeloid leukemia (AML). Anti-CD123 antibodies conjugated to Mal-PEG2000-DSPE were incorporated into normal niosomes (NS) via a ...
Fu-rong Liu +7 more
doaj +1 more source
Frontiers in Oncology, 2022 It is urgently necessary to reduce the adverse effects of chemotherapy while maintaining their cure high rates for children with acute lymphoblastic leukemia (ALL).
Yong Zhuang +22 more
doaj +1 more source
Myeloid sarcoma presenting as an isolated pancreatic mass in a 3‐year‐old child
JPGN Reports, EarlyView.Abstract Myeloid sarcoma (MS) is an extramedullary tumor of myeloid precursor cells, frequently associated with acute myeloid leukemia (AML), and rarely occurring in isolation. We present a child with obstructive jaundice secondary to a pancreatic head mass.
Jappmann Kaur Monga +7 more
wiley +1 more source
The involvement of multiple ABC transporters in daunorubicin efflux in Streptomyces coeruleorubidus
Microbial BiotechnologyStreptomyces genus produces a large number of antibiotics, which are always synthesized by specific biosynthetic gene clusters (BGCs). To resist autotoxicity, transporters encoded by genes located within BGC occasionally pump antibiotic along with ...
Jianxin Dong +5 more
doaj +1 more source
Acta Medica, 2002 A possible protective action of DMPS (a dithiol chelating agent) against chronic daunorubicin toxicity in rabbits in comparison with dexrazoxane was investigated.
Radomír Hrdina +6 more
doaj +1 more source
, 2010 High-throughput biological assays such as microarrays let us ask very detailed questions about how diseases operate, and promise to let us personalize therapy.
Baggerly, Keith A., Coombes, Kevin R.
core +1 more source
Modification of Daunorubicin-GnRH-III Bioconjugates With Oligoethylene Glycol Derivatives to Improve Solubility and Bioavailability for Targeted Cancer Chemotherapy [PDF]
, 2015 Daunorubicin-GnRH-III bioconjugates have recently been developed as drug delivery systems with potential applications in targeted cancer chemotherapy.
Bartos +32 more
core +1 more source
A Case of Cutaneous B Lymphoblastic Lymphoma With Multiple Cutaneous Tumors
JEADV Clinical Practice, EarlyView.ABSTRACT A 17‐year‐old Japanese male patient was referred to our hospital due to an erythematous tumor on part of the right mandible that had developed 3 months earlier, and similar tumors had appeared on the trunk and lower extremities. A complete blood count showed no specific abnormalities.
Tomomichi Shimizu +4 more
wiley +1 more source
Daunorubicin induced Stevens‐Johnson syndrome: A case report
Clinical Case Reports, 2021 Clinicians should consider the possible association of Daunorubicin with Stevens‐Johnson syndrome (SJS), administer it with caution and promptly evaluate all subsequently developing cutaneous reactions with a high index of suspicion for Stevens‐Johnson ...
Preeti Shakya, Amit Sharma Nepal
doaj +1 more source