Highly overlapping fluorescent signals become distinguishable in photon‐limited living organisms via advanced imaging with intelligent reconstruction. The resulting in vivo hyperspectral imaging capability reveals nanoplastic uptake and circulation in live zebrafish, providing a new approach for studying complex biological and environmental processes ...
Renjian Li +11 more
wiley +1 more source
Real-world deep brain stimulation programming practices for Parkinson's disease in India: variability, technology adoption, and emerging trends from a multicentre clinician survey across India. [PDF]
Pal PK +28 more
europepmc +1 more source
AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source
Beyond the Index Case: A Practical Framework for Cascade Family Screening in Hereditary Angioedema. [PDF]
Leung GK, Kan AK, Li PH.
europepmc +1 more source
Lithium Niobate Electro‐Optic Photonic Processor for Variational Quantum Eigensolver
An integrated lithium‐niobate‐on‐insulator ququart processor implements an electro‐optically controlled photonic variational quantum eigensolver using single photons encoded in four path modes. Bell‐basis‐emulating ququart projective measurements reduce measurement settings while achieving chemical‐accuracy‐level molecular‐energy estimation.
Jinil Lee +11 more
wiley +1 more source
Effect of operator experience level on clinical outcomes of indirect- and direct-bonding techniques: A single-center, open-label, quasi-randomized controlled clinical trial. [PDF]
Kono K +9 more
europepmc +1 more source
Physics‐Aware Machine‐Learning‐Driven Inverse Design of Broadband Ultra‐Open Acoustic Metamaterials
A physics‐aware machine‐learning framework enables inverse design of ultra‐open acoustic silencers by decoupling spectral and radial design spaces. The approach rapidly identifies broadband, compact, and highly ventilated architectures, while revealing hidden linear design rules that link geometry, impedance matching, and acoustic performance.
Zhiwei Yang +5 more
wiley +1 more source
A Single-Tube Nested PCR Method for <i>SMN1</i> Deletion Detection in Spinal Muscular Atrophy. [PDF]
Kosaka A +7 more
europepmc +1 more source
Differential Tissue‐Coupled Powering for Battery‐Free Injectable Electroceuticals
A thread‐like injectable neural stimulator is powered through differential tissue‐coupled powering (DTCP), which harvests RF‐frequency tissue potentials with an elongated receiver while preserving a injectable cross‐section. The system integrates an ASIC, stimulation electrodes, and a portable transmitter, enabling wireless peripheral nerve stimulation,
Han Wu +13 more
wiley +1 more source

