Results 61 to 70 of about 125,770 (300)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Effectiveness of neuromodulation in patients with drug-resistant epilepsy after failed surgical treatment

Эпилепсия и пароксизмальные состояния
Background. In case of ineffective conservative antiepileptic therapy, surgical treatment aimed at removing the epileptogenic focus may be applied. Resection procedures allow to eliminate seizures in most patients, but in 20–30% cases they persist or ...
F. A. Efremov, R. V. Agaev, S. A. Kim, G. I. Moisak, E. D. Anisimov, E. A. Khabarova, J. A. Rzaev   +6 more
doaj   +1 more source

Deep brain stimulation for chronic pain: a systematic review and meta-analysis

Frontiers in Human Neuroscience, 2023
BackgroundDeep brain stimulation (DBS) has shown promise in effectively treating chronic pain. This study aimed to assess the efficacy of DBS in this context.MethodsWe conducted a systematic literature search using PubMed, Scopus, and Web of Science ...
Nour Shaheen, Ahmed Shaheen, Abdelrahman Elgendy, Yarema B. Bezchlibnyk, Theresa Zesiewicz, Brian Dalm, Jennifer Jain, Alexander L. Green, Tipu Z. Aziz, Oliver Flouty   +9 more
doaj   +1 more source

A search for diffuse bands in the circumstellar envelopes of post-AGB stars

, 2007
In this work we present the results of a systematic search for diffuse bands (DBs, hereafter) in the circumstellar envelopes of a carefully selected sample of post-AGB stars.
Allamandola, Arellano, Arkhipova, Bakker, Bujarrabal, Clube, Cohen, Cox, Cox, Crawford, D. A. García Hernández, de Jong, Desmurs, Douglas, Drimmel, Ehrenfreund, Ehrenfreund, Fernie, Fernández de Córdoba, Fitzgerald, Foing, Fujii, Fulara, Galazutdinov, García-Lario, García-Lario, García-Lario, Gauba, Gauba, Gauba, Guarinos, Guarinos, Heap, Heger, Herbig, Herbig, Hrivnak, Hrivnak, Hrivnak, Hrivnak, Hrivnak, Hrivnak, Hrivnak, Hu, Hu, Iglesias-Groth, Iglesias-Groth, Jenniskens, Kendall, Kerr, Klochkova, Klochkova, Klochkova, Krelowski, Krelowski, Krelowski, Kwok, Kwok, Le Bertre, Le Bertre, Le Bertre, Leger, Lewis, M. A. Satorre, Maas, Malfait, Mauron, McCall, Megier, Meixner, Merrill, N. L. J. Cox, O. Suárez, Oudmaijer, P. García Lario, Parthasarathy, Pottasch, Prichet, R. Luna, Reddy, Reddy, Reed, Reyniers, Ruiterkamp, Salama, Salama, Sarre, Sarre, Scarrott, Snow, Snow, Suárez, te Lintel Hekkert, Thorburn, Torres-Peimbert, Turner, Van de Steene, Van der Veen, Van der Zwet, Van Winckel, Van Winckel, Volk, Weselak, Zacs, Zacs, Zacs, Zacs   +106 more
core   +2 more sources

Non-adherence to cardiovascular pharmacotherapy in Iraq assessed using 8-items Morisky questionnaire and analysis of dried blood spot samples [PDF]

, 2019
open access journalThe study evaluated the non-adherence to selected cardiovascular medications, atenolol, atorvastatin, bisoprolol, diltiazem, lisinopril, simvastatin and valsartan in Iraqi patients by applying a standardized Morisky questionnaire (8 ...
Alalaqi, Ahmed, Lawson, Graham, Obaid, Yaseen, Tanna, Sangeeta   +3 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Theory of Non-equilibrium Single Electron Dynamics in STM Imaging of Dangling Bonds on a Hydrogenated Silicon Surface

, 2011
During fabrication and scanning-tunneling-microscope (STM) imaging of dangling bonds (DBs) on a hydrogenated silicon surface, we consistently observed halo-like features around isolated DBs for specific imaging conditions.
J. M. Moison, Jason Pitters, L. Liu, Lucian Livadaru, Marco Taucer, Robert A. Wolkow   +5 more
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Systematic Evaluation of DBS Parameters in the Hemi-Parkinsonian Rat Model

Frontiers in Neuroscience, 2020
Electrical stimulation of the subthalamic nucleus (STN) is clinically employed to ameliorate several symptoms of manifest Parkinson’s Disease (PD). Stimulation parameters utilized by chronically implanted pulse generators comprise biphasic rectangular ...
Soheil Mottaghi, Soheil Mottaghi, Soheil Mottaghi, Oliver Buchholz, Oliver Buchholz, Ulrich G. Hofmann, Ulrich G. Hofmann, Ulrich G. Hofmann   +7 more
doaj   +1 more source

Latency Aware Drone Base Station Placement in Heterogeneous Networks

, 2017
Different from traditional static small cells, Drone Base Stations (DBSs) exhibit their own advantages, i.e., faster and cheaper to deploy, more flexibly reconfigured, and likely to have better communications channels owing to the presence of short-range
Ansari, Nirwan, Sun, Xiang
core   +1 more source