Results 31 to 40 of about 1,271,205 (290)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Online Journal of Health & Allied Sciences, 2011 The study was intended to find how the Primary Health Centers in the Selected Tribal Districts of Karnataka-India are functioning and to reveal their problems and prospects.
DC Nanjunda
doaj
A multiport isolated DC-DC converter [PDF]
2016 IEEE Applied Power Electronics Conference and Exposition (APEC), 2016 This paper presents a multi-port isolated DC-DC converter for DC applications. A three-port structure is presented, characterized with full bidirectional power flow and simple control. Galvanic isolation is achieved by means of a multi-winding medium frequency transformer which is a part of a resonant LLC converter.
Tran Yan-Kim, Dujic Drazen
openaire +2 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Modelling approaches for DC-DC converters with switched capacitors
, 2015 In this paper we review relevant problems in the modelling of DC-DC converters with switched capacitors. We study several approaches that overcome the exposed modelling difficulties, addressing ideal and nonideal cases and using dynamic equations that ...
Rapisarda, P. +2 more
core +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
A multilevel modular DC–DC converter topology [PDF]
Mathematics and Computers in Simulation, 2017 A multilevel modular DC-DC power conversion topology based on cascaded H-Bridge converters in a double П configuration is presented. The topology is intended to interconnect large power DC networks. A two level control hierarchy is used to regulate the DC voltage of each H-bridge module.
Ricardo Vidal +7 more
openaire +7 more sources
Double-boost DC to DC converter
, 2008 In this paper anew boost topology is proposed. The circuit is similar with two parallel boost dc-to-dc converters, but the two inductors are charged in parallel and release energy in series, thus enhancing the voltage boost ratio.
M.J. Case +8 more
core +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source