Results 41 to 50 of about 860,720 (284)

Optimization of DC - DC boost converter using fuzzy logic controller [PDF]

open access: yes, 2013
DC-DC converters are electronic devices used to change DC electrical power efficiently from one voltage level to another. Operation of the switching devices causes the inherently nonlinear characteristic of the DC-DC converters including one known as
Soluman Ahtiwish, Aimen Khalifa
core  

Synthesis of input-rectifierless AC-DC converters [PDF]

open access: yes, 2001
This paper discusses the basic construction procedure and topological possibilities of creating ac/dc converters out of simple dc/dc conveners. It is shown that two separately controlled dc/dc conveners are sufficient for producing a regulated dc output ...
Lai, YM   +4 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

A family of DC-DC converters deduced from impedance source DC-DC converters for high step-up conversion [PDF]

open access: yes, 2016
This paper introduces a family of DC-DC converters based on impedance source DC-DC converters. The derived topology is suitable for high voltage step-up ratios.
Li, Fei, Liu, Hongchen, Wheeler, Patrick
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Functioning of Primary Health Centers in the Selected Tribal Districts of Karnataka-India: Some Preliminary Observations

open access: yesOnline Journal of Health & Allied Sciences, 2011
The study was intended to find how the Primary Health Centers in the Selected Tribal Districts of Karnataka-India are functioning and to reveal their problems and prospects.
DC Nanjunda
doaj  

Efficient LDO-Assisted DC/DC buck converter for integrated power management system [PDF]

open access: yes, 2016
DC-DC Switching Converters; Voltage Linear Regulators; Linear-Assisted DC-DC Voltage Regulators.Postprint (published ...
Martínez García, Herminio
core  

Generalized small-signal modelling of dual active bridge DC/DC converter [PDF]

open access: yes, 2018
this paper presents a novel generalised approach of the small-signal modelling of dual active bridge (DAB) DC/DC converter. The adopted analysis is based on a per-unit fundamental frequency representation of the DAB. The outcome of the proposed modelling
Aboushady, Ahmed A.   +4 more
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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