Results 41 to 50 of about 1,271,205 (290)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Traumatic arteriovenous fistula of the left ulnar artery and vein

open access: yesIbom Medical Journal
Traumatic arteriovenous fistulae (AVFs) result from a puncture of adjacent artery and vein, leading to a low-resistance, high-pressure gradient with consequent high flows.
Obiozor AA, Obiozor DC
doaj   +1 more source

indigo-dc/udocker: udocker 1.3.4

open access: yes, 2021
udocker v1.3.4 see the changelog and the documentation for further information. Changelog: https://github.com/indigo-dc/udocker/blob/master/CHANGELOG.md Documentation: https://indigo-dc.github.io/udocker/ udocker release for Python 2.7 and >= 3.6 ...
samuelbernardolip   +21 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Voltage Control for DC-DC Converters [PDF]

open access: yes, 2018
In this paper, we discuss voltage control method for buck converter operating in continuous conduction mode (CCM) using analog feedback system. The aim of this work is to control the output voltage of a buck converter during the variation in load current. This is obtained using analog feedback made with operational amplifier (Opamp).
Usman Rahat   +2 more
openaire   +2 more sources

DC-DC Converter Design Issues for High-Efficient DC Microgrid

open access: yes, 2019
In this article, the electrical properties, as well as the economic aspects of the modular and non-modular solution of the DC-DC photovoltaic converter for DC microgrid subsystem, are described.
Michal Frivaldsky, Jan Morgos
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Treatment of sleep-disordered breathing with positive airway pressure devices: technology update

open access: yesMedical Devices: Evidence and Research, 2015
Karin Gardner Johnson, Douglas Clark Johnson Department of Medicine, Baystate Medical Center, Springfield, MA, USA Abstract: Many types of positive airway pressure (PAP) devices are used to treat sleep-disordered breathing including obstructive sleep ...
Johnson KG, Johnson DC
doaj  

Cancer Mortality for a Single Race in Low Versus High Elevation Counties in the U.S.

open access: yesDose-Response, 2011
A previous study compared cancer mortality in the six lowest versus six highest elevations in the U.S. for all races. This study looks at a single race since death rates tend to vary by race. In this ecological study, cancer mortality rates were compared
John Hart DC, MHSc
doaj   +1 more source

5 Reasons Why Scoliosis X-Rays Are Not Harmful

open access: yesDose-Response, 2020
Radiographic imaging for scoliosis screening, diagnosis, treatment, and management is the gold standard assessment tool. Scoliosis patients receive many repeat radiographs, typically 10-25 and as many as 40-50, equating to a maximum 50 mGy of cumulative ...
Paul A. Oakley DC, MSc   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy