Results 71 to 80 of about 861,339 (283)

Therapeutic Strategies to Tackle Burnout and Emotional Exhaustion in Frontline Medical Staff: Narrative Review

open access: yesPsychology Research and Behavior Management, 2021
Daniel C McFarland,1 Fay Hlubocky2 1Department of Medicine, Northwell Health Cancer Institute, Lenox Hill Hospital, New York, NY, USA; 2Department of Medicine, Section of Hematology/Oncology, University of Chicago, MacLean Center for Clinical Medical ...
McFarland DC, Hlubocky F
doaj  

Efficient LDO–assisted DC/DC buck converter for power management integrated systems [PDF]

open access: yes, 2017
This paper shows the modeling of a linear–assisted or hybrid (linear & switching) DC–DC converters. In this kind of converters, an auxiliary linear regulator is used, which objective is to cancel the ripple at the output voltage and provide fast ...
Martínez García, Herminio
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Exercise-induced pulmonary hemorrhage: where are we now?

open access: yesVeterinary Medicine: Research and Reports, 2016
David C Poole,1,2 Howard H Erickson1 1Department of Anatomy and Physiology, 2Department of Kinesiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA Abstract: As the Thoroughbreds race for the final stretch, 44 hooves ...
Poole DC, Erickson HH
doaj  

Multi-megawatt inverter/converter technology for space power applications [PDF]

open access: yes
Large power conditioning mass reductions will be required to enable megawatt power systems envisioned by the Strategic Defense Initiative, the Air Force, and NASA.
Baumann, Eric D.   +3 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Targeted treatment of advanced ovarian cancer: spotlight on rucaparib

open access: yesTherapeutics and Clinical Risk Management, 2018
Diana C Pearre, Krishnansu S Tewari Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, University of California, Irvine Medical Center, Orange, CA, USA Abstract: The last 2 years have ushered in a new era in ovarian cancer ...
Pearre DC, Tewari KS
doaj  

DC/DC converter [PDF]

open access: yes, 2011
Tato práce se zabývá tranzistorovými měniči především čtyřkvadrantovým můstkem. Převážná část práce pojednává o budičích tranzistorů a možném způsobu řízení měniče. Součástí práce je i návrh řídící elektroniky a regulační struktury.
Němec, Martin
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

First- and second-order dynamic equations with impulse

open access: yesAdvances in Difference Equations, 2005
We present existence results for discontinuous first- and continuous second-order dynamic equations on a time scale subject to fixed-time impulses and nonlinear boundary conditions.
Atici FM, Biles DC
doaj  

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