Results 71 to 80 of about 1,271,205 (290)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

EMT simulation of an MTDC system integrating Modular Multilevel DC/DC converter with DC voltage control [PDF]

open access: yes
The increasing demand to utilize renewable energy necessitates the transmission of power over long distances. HVDC technology has emerged as the optimal solution for this purpose due to fewer losses and good economic factors.
COLAS, Frédéric   +3 more
core  

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli   +5 more
wiley   +1 more source

DC-091122F

open access: yes, 2009
First, DC is asked to comment on different motion events exemplified with toys. Afterwards, imagining two children playing hide and seek, sentences on topological relations are elicited.
Femmy, DC
core  

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

Update on rescue therapies in patients with lamivudine-resistant chronic hepatitis B

open access: yesDrug Design, Development and Therapy, 2013
Daniel C Chao, Ke-Qin HuDivision of Gastroenterology and Hepatology, University of California, Irvine Medical Center, Orange, CA, USAAbstract: Chronic hepatitis B continues to be a global problem, with an estimated 240 million cases according to the
Chao DC, Hu KQ
doaj  

Improvement of stability and performance in DC-DC resonant converters

open access: yes, 2002
This report addresses the use of linear robust control theory in control of Dc-Dc switching converters. A typical fifth-order DC-DC high power converter is considered as a study system. Satisfactory stability and satisfactory performance, in the presence
Bevrani, Hassan
core  

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao   +6 more
wiley   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan   +14 more
wiley   +1 more source

The Scoliosis Quandary: Are Radiation Exposures From Repeated X-Rays Harmful?

open access: yesDose-Response, 2019
X-rays have been the gold standard for diagnosis, evaluation, and management of spinal scoliosis for decades as other assessment methods are indirect, too expensive, or not practical in practice. The average scoliosis patient will receive 10 to 25 spinal
Paul A. Oakley DC, MSc   +2 more
doaj   +1 more source

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