Results 11 to 20 of about 20,385 (185)

Unmasking the immune microecology of ductal carcinoma in situ with deep learning

open access: yesnpj Breast Cancer, 2021
Despite increasing evidence supporting the clinical relevance of tumour infiltrating lymphocytes (TILs) in invasive breast cancer, TIL spatial variability within ductal carcinoma in situ (DCIS) samples and its association with progression are not well ...
Priya Lakshmi Narayanan   +12 more
doaj   +1 more source

Modeling the natural history of ductal carcinoma in situ based on population data

open access: yesBreast Cancer Research, 2020
Background The incidence of ductal carcinoma in situ (DCIS) has increased substantially since the introduction of mammography screening. Nevertheless, little is known about the natural history of preclinical DCIS in the absence of biopsy or complete ...
Sarocha Chootipongchaivat   +10 more
doaj   +1 more source

Is palpable DCIS more aggressive than screen-detected DCIS?

open access: yesSurgery Open Science, 2023
Palpable ductal carcinoma in-situ (pDCIS) is a subset of DCIS presenting with a clinical mass. We hypothesized pDCIS would have more aggressive clinical and pathological features, and higher rates of recurrence and upgrade to invasive disease compared to screen-detected DCIS.We performed a retrospective analysis of female patients (age 28-76) with DCIS
Nina Balac   +9 more
openaire   +3 more sources

Immune microenvironment in ductal carcinoma in situ: a comparison with invasive carcinoma of the breast

open access: yesBreast Cancer Research, 2020
Background The immune microenvironment in ductal carcinoma in situ (DCIS) and its significance are not well established. This study was conducted to evaluate the immune microenvironment of DCIS including the composition of tumor-infiltrating lymphocyte ...
Milim Kim   +5 more
doaj   +1 more source

Different distribution of breast ductal carcinoma in situ, ductal carcinoma in situ with microinvasion, and invasion breast cancer

open access: yesWorld Journal of Surgical Oncology, 2012
Background Breast ductal cancer in situ (DCIS) can recur or progress to invasive ductal cancer (IDC), and the interim stage include DCIS with microinvasion (DCIS-Mi).
Wei Zhang   +9 more
doaj   +1 more source

Molecular signatures of in situ to invasive progression for basal-like breast cancers: An integrated mouse model and human DCIS study

open access: yesnpj Breast Cancer, 2022
Ductal carcinoma in situ (DCIS) of the breast is a non-obligate precursor of Invasive Ductal Carcinoma (IDC) and thus the identification of features that may predict DCIS progression would be of potential clinical value.
Aatish Thennavan   +4 more
doaj   +1 more source

Transcriptome analysis reveals differences in cell cycle, growth and migration related genes that distinguish fibroblasts derived from pre-invasive and invasive breast cancer

open access: yesFrontiers in Oncology, 2023
Background/IntroductionAs the most common form of pre-invasive breast cancer, ductal carcinoma in situ (DCIS) affects over 50,000 women in the US annually.
Wei Bin Fang   +13 more
doaj   +1 more source

Learning protein binding affinity using privileged information

open access: yesBMC Bioinformatics, 2018
Background Determining protein-protein interactions and their binding affinity are important in understanding cellular biological processes, discovery and design of novel therapeutics, protein engineering, and mutagenesis studies.
Wajid Arshad Abbasi   +3 more
doaj   +1 more source

Is there a difference in FDG PET findings of invasive ductal carcinoma of the breast with and without coexisting DCIS? [PDF]

open access: yesAsia Oceania Journal of Nuclear Medicine and Biology, 2020
Objective(s): Studies have reported that invasive ductal carcinoma (IDC) with coexisting ductal carcinoma in situ (DCIS) show lower metastatic potential and recurrence and better overall survival than pure IDC.
Ismet Sarikaya   +4 more
doaj   +1 more source

Mechanostimulation of breast myoepithelial cells induces functional changes associated with DCIS progression to invasion

open access: yesnpj Breast Cancer, 2022
Women with ductal carcinoma in situ (DCIS) have an increased risk of progression to invasive breast cancer. Although not all women with DCIS will progress to invasion, all are treated as such, emphasising the need to identify prognostic biomarkers.
Mary-Kate Hayward   +7 more
doaj   +1 more source

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