Results 21 to 30 of about 29,583 (248)

A mouse SWATH-mass spectrometry reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts

Disease Models & Mechanisms, 2020
SWATH-mass spectrometry (MS) enables accurate and reproducible proteomic profiling in multiple model organisms including the mouse. Here, we present a comprehensive mouse reference spectral library (MouseRefSWATH) that permits quantification of up to 10 ...
Lukas Krasny, Philip Bland, Jessica Burns, Nadia Carvalho Lima, Peter T. Harrison, Laura Pacini, Mark L. Elms, Jian Ning, Victor Garcia Martinez, Yi-Ru Yu, Sophie E. Acton, Ping-Chih Ho, Fernando Calvo, Amanda Swain, Beatrice A. Howard, Rachael C. Natrajan, Paul H. Huang   +16 more
doaj   +1 more source

More microinvasive foci in larger tumours of breast ductal carcinoma in situ

Singapore Medical Journal, 2023
Introduction: Microinvasion (Mi) is often thought to be an interim stage between ductal carcinoma in situ (DCIS) and invasive ductal carcinoma. This study aimed to investigate the potential influence of Mi on survival and assess its correlations with ...
Xiao-Yang Chen, Aye Aye Thike, Johnathan Xiande Lim, Boon Huat Bay, Puay Hoon Tan   +4 more
doaj   +1 more source

Detection of Data Scarce Malware Using One-Shot Learning With Relation Network

IEEE Access, 2023
Malware has evolved to pose a major threat to information security. Efficient anti-malware software is essential in safeguarding confidential information from these threats. However, identifying malware continues to be a challenging task. Signature-based
Faiza Babar Khan, Muhammad Hanif Durad, Asifullah Khan, Farrukh Aslam Khan, Sajjad Hussain Chauhdary, Mohammed Alqarni   +5 more
doaj   +1 more source

Development of a Nomogram-Based Clinical Estimation Model for Pathological Upstaging in Patients With Preoperative Ductal Carcinoma In Situ. [PDF]

Kaohsiung J Med Sci
ABSTRACT Preoperative diagnosis of ductal carcinoma in situ (DCIS) may be followed by pathological upstaging to invasive ductal carcinoma (IDC) upon surgical excision, a discrepancy that significantly impacts surgical planning and decisions regarding sentinel lymph node biopsy (SLNB).
Chen YH, Li CL, Yang PF, Hsiao HH, Chen FM, Moi SH.   +5 more
europepmc   +2 more sources

Relationship between altered myoepithelial phenotype and the inflammatory cell infiltrate in progression of DCIS [PDF]

, 2015
The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorChanges in the microenvironment have been implicated in the transition of pre ...
Ahmed, Khairiya O
core   +2 more sources

Artificial Intelligence-Assisted Invasion Risk Scoring in Tru-Cut Biopsies of Ductal Carcinoma in Situ; Predictive Role of Estrogen Receptor and HER2 Expression [PDF]

Türk Patoloji Dergisi
Objective: Invasion can be detected in up to 50% of excision specimens in cases diagnosed with ductal carcinoma in-situ (DCIS) in tru-cut biopsies. The predicting of invasion is critical for managing the treatment.
Evren UZUN, Kubra BULUT
doaj   +1 more source

A Lock Free Approach To Parallelize The Cellular Potts Model: Application To Ductal Carcinoma In Situ

Journal of Integrative Bioinformatics, 2020
In the field of computational biology, in order to simulate multiscale biological systems, the Cellular Potts Model (CPM) has been used, which determines the actions that simulated cells can perform by determining a hamiltonian of energy that takes into ...
Tomeu Antonio J., Salguero Alberto G.
doaj   +1 more source

Modeling the natural history of ductal carcinoma in situ based on population data

Breast Cancer Research, 2020
Background The incidence of ductal carcinoma in situ (DCIS) has increased substantially since the introduction of mammography screening. Nevertheless, little is known about the natural history of preclinical DCIS in the absence of biopsy or complete ...
Sarocha Chootipongchaivat, Nicolien T. van Ravesteyn, Xiaoxue Li, Hui Huang, Harald Weedon-Fekjær, Marc D. Ryser, Donald L. Weaver, Elizabeth S. Burnside, Brandy M. Heckman-Stoddard, Harry J. de Koning, Sandra J. Lee   +10 more
doaj   +1 more source

The dilemma of DCIS

The Breast, 2007
The increasingly frequent diagnosis of ductal carcinoma in situ (DCIS) presents a major clinical dilemma. Our inability to predict which DCIS will progress to invasive cancer or the time interval in which recurrent DCIS or invasive cancer will occur has resulted in treatments ranging from mastectomy to excision and observation being offered to patients.
Monica, Morrow, Martin J, O'Sullivan
openaire   +2 more sources

Molecular subtyping of DCIS : heterogeneity of breast cancer reflected in pre-invasive disease [PDF]

, 2010
Background: Molecular profiling has identified at least four subtypes of invasive breast carcinoma, which exhibit distinct clinical behaviour. There is good evidence now that DCIS represents the non-obligate precursor to invasive breast cancer and ...
Jones, J. Louise, J L Jones, Jane Warwick, S E Clark, Warwick, Jane, R L Bowen, Clark, S. E., S W Duffy, Duffy, Stephen W., Bowen, Rebecca, Carpenter, R., J Warwick, R Carpenter   +12 more
core   +1 more source