Results 21 to 30 of about 6,508 (192)

Molecular signatures of in situ to invasive progression for basal-like breast cancers: An integrated mouse model and human DCIS study

npj Breast Cancer, 2022
Ductal carcinoma in situ (DCIS) of the breast is a non-obligate precursor of Invasive Ductal Carcinoma (IDC) and thus the identification of features that may predict DCIS progression would be of potential clinical value.
Aatish Thennavan, Susana Garcia-Recio, Siyao Liu, Xiaping He, Charles M. Perou   +4 more
doaj   +1 more source

Incidental DCIS within a fibroadenoma

BMJ Case Reports, 2023
A female in her early 20s was referred to the breast-endocrine surgeons with a self-detected tender left breast lump on the background of a family history of breast cancer. A physical examination revealed a rubbery and mobile mass in the left upper breast.
Arnold Chen, Shaveen Kanakaratne, Philip Britten-Jones, Janne Bingham   +3 more
openaire   +3 more sources

Transcriptome analysis reveals differences in cell cycle, growth and migration related genes that distinguish fibroblasts derived from pre-invasive and invasive breast cancer

Frontiers in Oncology, 2023
Background/IntroductionAs the most common form of pre-invasive breast cancer, ductal carcinoma in situ (DCIS) affects over 50,000 women in the US annually.
Wei Bin Fang, Marcela Medrano, Paige Cote, Mike Portsche, Vinamratha Rao, Yan Hong, Fariba Behbod, Jennifer R. Knapp, Jennifer R. Knapp, Clark Bloomer, Janelle Noel-Macdonnell, Janelle Noel-Macdonnell, Nikki Cheng, Nikki Cheng   +13 more
doaj   +1 more source

Does Existence of Ductal Carcinoma In Situ Accompanying Invasive Ductal Carcinoma Lead to Different Clinicopathological Features and Clinical Outcome? Report of a Breast Cancer Registry [PDF]

Middle East Journal of Cancer, 2022
Background: Ductal carcinoma in situ (DCIS) is widely recognized as the precursor of invasive ductal carcinoma (IDC). We aimed to compare clinicopathological characteristics and prognosis between IDC with and without coexisting DCIS stratified by ...
Sedigheh Tahmasebi, Baharak Shahin, Masoumeh Ghoddusi Johari, Majid Akrami, Vahid Zanguri, Abdolrasoul Talei, Zahra Keumarsi, Nazanin Karimaghaei   +7 more
doaj   +1 more source

Prognostic significance of cathepsin V (CTSV/CTSL2) in breast ductal carcinoma in situ

, 2020
Aims: Cathepsin V (CTSV/CTSL2) is a lysosomal cystine proteinase and plays a role in extracellular matrix degradation. It is associated with poor prognosis in invasive breast cancer (IBC), but its role in breast ductal carcinoma in situ (DCIS) remains ...
Miligy, Islam M., Rakha, Emad A., Green, Andrew R., Toss, Michael S., Aneja, Ritu, Ellis, Ian O., Mittal, Karuna, Gorringe, Kylie L.   +7 more
core   +1 more source

Mechanostimulation of breast myoepithelial cells induces functional changes associated with DCIS progression to invasion

npj Breast Cancer, 2022
Women with ductal carcinoma in situ (DCIS) have an increased risk of progression to invasive breast cancer. Although not all women with DCIS will progress to invasion, all are treated as such, emphasising the need to identify prognostic biomarkers.
Mary-Kate Hayward, Michael D. Allen, Jennifer J. Gomm, Iain Goulding, Clare L. Thompson, Martin M. Knight, John F. Marshall, J. Louise Jones   +7 more
doaj   +1 more source

Learning protein binding affinity using privileged information

BMC Bioinformatics, 2018
Background Determining protein-protein interactions and their binding affinity are important in understanding cellular biological processes, discovery and design of novel therapeutics, protein engineering, and mutagenesis studies.
Wajid Arshad Abbasi, Amina Asif, Asa Ben-Hur, Fayyaz ul Amir Afsar Minhas   +3 more
doaj   +1 more source

Contrasting DCIS and invasive breast cancer by subtype suggests basal-like DCIS as distinct lesions

, 2020
International audienceDuctal carcinoma in situ (DCIS) is a non-invasive type of breast cancer with highly variable potential of becoming invasive and affecting mortality.
Kristensen, Vessela, N, Frigessi, Arnoldo, Geitvik, Gry, Aarum, Skjerven, Helle, Kristine, Lien, Tonje, G, Lingjærde, Ole, Christian, Bathen, Tone, F, Wärnberg, Fredrik, Borgen, Elin, Mælandsmo, Gunhild, Mari, Sauer, Torill, Daidone, Maria, Grazia, Hofvind, Solveig, Bergholtz, Helga, Geisler, Jürgen, Engebråten, Olav, Russnes, Hege, Sørlie, Therese, Garred, Øystein, Naume, Bjørn, Tost, Jörg, Hartmann-Johnsen, Olaf, Johan, Langerød, Anita, Swanson, David, M, Schlichting, Ellen, Børresen-Dale, Anne, Lise   +25 more
core   +2 more sources

Identification of biomarkers in ductal carcinoma in situ of the breast with microinvasion

BMC Cancer, 2008
Background Widespread use of mammography in breast cancer screening has led to the identification of increasing numbers of patients with ductal carcinoma in situ (DCIS).
Iyama Ken-ichi, Honda Yumi, Ibusuki Mutsuko, Kawasoe Teru, Toyama Tatsuya, Zhang Zhenhuan, Yamamoto Yutaka, Okumura Yasuhiro, Yamashita Hiroko, Iwase Hirotaka   +9 more
doaj   +1 more source

Clinicopathological features and prognostic differences of ductal carcinoma in situ with ductal carcinoma in situ with microinvasion

Di-san junyi daxue xuebao, 2020
Objective To determine the clinicopathological features and prognostic differences between ductal carcinoma in situ (DCIS) and ductal carcinoma in situ with microinvasion (DCIS-MI) of breast cancer. Methods A cohort of 489 female patients with surgically
LIU Jing, ZHANG Ye, YAN Wenting, ZHONG Ling, TAN Xuanni   +4 more
doaj   +1 more source