Results 31 to 40 of about 29,583 (248)

Unmasking the immune microecology of ductal carcinoma in situ with deep learning

npj Breast Cancer, 2021
Despite increasing evidence supporting the clinical relevance of tumour infiltrating lymphocytes (TILs) in invasive breast cancer, TIL spatial variability within ductal carcinoma in situ (DCIS) samples and its association with progression are not well ...
Priya Lakshmi Narayanan, Shan E. Ahmed Raza, Allison H. Hall, Jeffrey R. Marks, Lorraine King, Robert B. West, Lucia Hernandez, Naomi Guppy, Mitch Dowsett, Barry Gusterson, Carlo Maley, E. Shelley Hwang, Yinyin Yuan   +12 more
doaj   +1 more source

The road towards conquering DCIS overtreatment [PDF]

, 2021
The objectives of this thesis, aimed to reduce overtreatment of ductal carcinoma in situ (DCIS) of the breast, were : 1) to evaluate the risk of underestimation after a diagnosis of DCIS and the interrater reliability in the histopathological ...
Groen, E.J.
core  

Immune microenvironment in ductal carcinoma in situ: a comparison with invasive carcinoma of the breast

Breast Cancer Research, 2020
Background The immune microenvironment in ductal carcinoma in situ (DCIS) and its significance are not well established. This study was conducted to evaluate the immune microenvironment of DCIS including the composition of tumor-infiltrating lymphocyte ...
Milim Kim, Yul Ri Chung, Hyun Jeong Kim, Ji Won Woo, Soomin Ahn, So Yeon Park   +5 more
doaj   +1 more source

Different distribution of breast ductal carcinoma in situ, ductal carcinoma in situ with microinvasion, and invasion breast cancer

World Journal of Surgical Oncology, 2012
Background Breast ductal cancer in situ (DCIS) can recur or progress to invasive ductal cancer (IDC), and the interim stage include DCIS with microinvasion (DCIS-Mi).
Wei Zhang, Er-li Gao, Yi-li Zhou, Qi Zhai, Zhang-yong Zou, Gui-long Guo, Guo-rong Chen, Hua-min Zheng, Guan-li Huang, Xiao-hua Zhang   +9 more
doaj   +1 more source

International variation in management of screen-detected ductal carcinoma in situ of the breast [PDF]

, 2014
Results Twelve countries contributed data from a total of 15 screening programmes, all from Europe except the United States of America and Japan. Among women aged 50-69 years, 7,176,050 screening tests and 5324 screen-detected DCIS were reported. From 21%
Fracheboud, J. (Jacques), Bulliard, J.-L. (Jean-Luc), Fitzpatrick, Patricia, Fracheboud, Jacques, Hofvind, S, Hofvind, S., Von Euler-Chelpin, M. (My), Anttila, A, Kerlikowske, Karla, Bulliard, J.L., Segnan, Nereo, Ponti, A, Ascunce, Nieves, James, T., Taplin, S. (Stephen), Scharpantgen, Astrid, Kerlikowske, K, Hofvind, Solveig, Segnan, N. (Nereo), Segnan, N., Vidal, C. (Carmen), Ponti, A., Salas, D. (Dolores), Taplin, S., James, T, Májek, O., Bulliard, Jean-Luc, Taplin, Stephen, Vidal, C, Segnan, N, Hofvind, S. (Solveig), von Euler-Chelpin, My, Vidal, Carmen, Taplin, S, Kawai, M. (Masaaki), Anttila, A., Scharpantgen, A., Scharpantgen, A. (A.), group, ICSN DCIS Working, Anttila, A. (Ahti), Lynge, E, Ascunce, N, Ponti, A. (Antonio), Salas, Dolores, James, Ted, Májek, O. (Ondřej), Fitzpatrick, P, Vidal, C., Mano, MP, Ascunce, N., Bulliard, JL, Kerlikowske, K., Kawai, M., von Euler-Chelpin, M, Kawai, M, Salas, D., Mano, M.P., Ascunce, N. (Nieves), von Euler-Chelpin, M., Mano, Maria Piera, Majek, O, James, T. (Ted), Anttila, Ahti, Fracheboud, J., Ponti, Antonio, Kawai, Masaaki, Kerlikowske, K. (Karla), Scharpantgen, A, Lynge, E., Lynge, Elsebeth, Májek, Ondřej, Fitzpatrick, P. (Patricia), Fitzpatrick, P., Salas, D, Lynge, E. (Elsebeth), Mano, M.P. (Maria Piera), Taplin S, Fracheboud J, Bulliard JL, Hofvind S, James T, Kerlikowske K, Segnan N, Kawai M, Ponti A, Mano MP, Anttila A, Májek O, von Euler-Chelpin M, Scharpantgen A, Ascunce N, Fitzpatrick P, Vidal C, Salas D, Lynge E   +94 more
core   +1 more source

Learning protein binding affinity using privileged information

BMC Bioinformatics, 2018
Background Determining protein-protein interactions and their binding affinity are important in understanding cellular biological processes, discovery and design of novel therapeutics, protein engineering, and mutagenesis studies.
Wajid Arshad Abbasi, Amina Asif, Asa Ben-Hur, Fayyaz ul Amir Afsar Minhas   +3 more
doaj   +1 more source

Incidental DCIS within a fibroadenoma

BMJ Case Reports, 2023
A female in her early 20s was referred to the breast-endocrine surgeons with a self-detected tender left breast lump on the background of a family history of breast cancer. A physical examination revealed a rubbery and mobile mass in the left upper breast.
Arnold Chen, Shaveen Kanakaratne, Philip Britten-Jones, Janne Bingham   +3 more
openaire   +3 more sources

Molecular signatures of in situ to invasive progression for basal-like breast cancers: An integrated mouse model and human DCIS study

npj Breast Cancer, 2022
Ductal carcinoma in situ (DCIS) of the breast is a non-obligate precursor of Invasive Ductal Carcinoma (IDC) and thus the identification of features that may predict DCIS progression would be of potential clinical value.
Aatish Thennavan, Susana Garcia-Recio, Siyao Liu, Xiaping He, Charles M. Perou   +4 more
doaj   +1 more source

Does Existence of Ductal Carcinoma In Situ Accompanying Invasive Ductal Carcinoma Lead to Different Clinicopathological Features and Clinical Outcome? Report of a Breast Cancer Registry [PDF]

Middle East Journal of Cancer, 2022
Background: Ductal carcinoma in situ (DCIS) is widely recognized as the precursor of invasive ductal carcinoma (IDC). We aimed to compare clinicopathological characteristics and prognosis between IDC with and without coexisting DCIS stratified by ...
Sedigheh Tahmasebi, Baharak Shahin, Masoumeh Ghoddusi Johari, Majid Akrami, Vahid Zanguri, Abdolrasoul Talei, Zahra Keumarsi, Nazanin Karimaghaei   +7 more
doaj   +1 more source

Mechanostimulation of breast myoepithelial cells induces functional changes associated with DCIS progression to invasion

npj Breast Cancer, 2022
Women with ductal carcinoma in situ (DCIS) have an increased risk of progression to invasive breast cancer. Although not all women with DCIS will progress to invasion, all are treated as such, emphasising the need to identify prognostic biomarkers.
Mary-Kate Hayward, Michael D. Allen, Jennifer J. Gomm, Iain Goulding, Clare L. Thompson, Martin M. Knight, John F. Marshall, J. Louise Jones   +7 more
doaj   +1 more source