Results 31 to 40 of about 28,831 (253)

Mechanostimulation of breast myoepithelial cells induces functional changes associated with DCIS progression to invasion

npj Breast Cancer, 2022
Women with ductal carcinoma in situ (DCIS) have an increased risk of progression to invasive breast cancer. Although not all women with DCIS will progress to invasion, all are treated as such, emphasising the need to identify prognostic biomarkers.
Mary-Kate Hayward, Michael D. Allen, Jennifer J. Gomm, Iain Goulding, Clare L. Thompson, Martin M. Knight, John F. Marshall, J. Louise Jones   +7 more
doaj   +1 more source

Incidental DCIS within a fibroadenoma

BMJ Case Reports, 2023
A female in her early 20s was referred to the breast-endocrine surgeons with a self-detected tender left breast lump on the background of a family history of breast cancer. A physical examination revealed a rubbery and mobile mass in the left upper breast.
Arnold Chen, Shaveen Kanakaratne, Philip Britten-Jones, Janne Bingham   +3 more
openaire   +3 more sources

International variation in management of screen-detected ductal carcinoma in situ of the breast [PDF]

, 2014
Results Twelve countries contributed data from a total of 15 screening programmes, all from Europe except the United States of America and Japan. Among women aged 50-69 years, 7,176,050 screening tests and 5324 screen-detected DCIS were reported. From 21%
Fracheboud, J. (Jacques), Bulliard, J.-L. (Jean-Luc), Fitzpatrick, Patricia, Fracheboud, Jacques, Hofvind, S, Hofvind, S., Von Euler-Chelpin, M. (My), Anttila, A, Kerlikowske, Karla, Bulliard, J.L., Segnan, Nereo, Ponti, A, Ascunce, Nieves, James, T., Taplin, S. (Stephen), Scharpantgen, Astrid, Kerlikowske, K, Hofvind, Solveig, Segnan, N. (Nereo), Segnan, N., Vidal, C. (Carmen), Ponti, A., Salas, D. (Dolores), Taplin, S., James, T, Májek, O., Bulliard, Jean-Luc, Taplin, Stephen, Vidal, C, Segnan, N, Hofvind, S. (Solveig), von Euler-Chelpin, My, Vidal, Carmen, Taplin, S, Kawai, M. (Masaaki), Anttila, A., Scharpantgen, A., Scharpantgen, A. (A.), group, ICSN DCIS Working, Anttila, A. (Ahti), Lynge, E, Ascunce, N, Ponti, A. (Antonio), Salas, Dolores, James, Ted, Májek, O. (Ondřej), Fitzpatrick, P, Vidal, C., Mano, MP, Ascunce, N., Bulliard, JL, Kerlikowske, K., Kawai, M., von Euler-Chelpin, M, Kawai, M, Salas, D., Mano, M.P., Ascunce, N. (Nieves), von Euler-Chelpin, M., Mano, Maria Piera, Majek, O, James, T. (Ted), Anttila, Ahti, Fracheboud, J., Ponti, Antonio, Kawai, Masaaki, Kerlikowske, K. (Karla), Scharpantgen, A, Lynge, E., Lynge, Elsebeth, Májek, Ondřej, Fitzpatrick, P. (Patricia), Fitzpatrick, P., Salas, D, Lynge, E. (Elsebeth), Mano, M.P. (Maria Piera)   +75 more
core   +1 more source

Prolyl-4-hydroxylase Α subunit 2 (P4HA2) expression is a predictor of poor outcome in breast ductal carcinoma in situ (DCIS) [PDF]

, 2018
© 2018, Cancer Research UK. Background: Extracellular matrix (ECM) plays a crucial role in tumour behaviour. Prolyl-4-hydroxlase-A2 (P4HA2) is a key enzyme in ECM remodelling.
Andrew R. Green, Michael S. Toss, Emad A. Rakha, Khout, Hazem, Toss, Michael S., Rakha, Emad, Abdulbaqi AlKawaz, Miligy, Islam M., Islam M. Miligy, Alkawaz, Abdulbaqi, Kylie L. Gorringe, Green, Andrew R., Hazem Khout, Ian O. Ellis, Ellis, Ian O., Gorringe, Kylie L.   +15 more
core   +1 more source

Transcriptome analysis reveals differences in cell cycle, growth and migration related genes that distinguish fibroblasts derived from pre-invasive and invasive breast cancer

Frontiers in Oncology, 2023
Background/IntroductionAs the most common form of pre-invasive breast cancer, ductal carcinoma in situ (DCIS) affects over 50,000 women in the US annually.
Wei Bin Fang, Marcela Medrano, Paige Cote, Mike Portsche, Vinamratha Rao, Yan Hong, Fariba Behbod, Jennifer R. Knapp, Jennifer R. Knapp, Clark Bloomer, Janelle Noel-Macdonnell, Janelle Noel-Macdonnell, Nikki Cheng, Nikki Cheng   +13 more
doaj   +1 more source

Prognostic significance of cathepsin V (CTSV/CTSL2) in breast ductal carcinoma in situ

, 2020
Aims: Cathepsin V (CTSV/CTSL2) is a lysosomal cystine proteinase and plays a role in extracellular matrix degradation. It is associated with poor prognosis in invasive breast cancer (IBC), but its role in breast ductal carcinoma in situ (DCIS) remains ...
Miligy, Islam M., Rakha, Emad A., Green, Andrew R., Toss, Michael S., Aneja, Ritu, Ellis, Ian O., Mittal, Karuna, Gorringe, Kylie L.   +7 more
core   +1 more source

Contrasting DCIS and invasive breast cancer by subtype suggests basal-like DCIS as distinct lesions

, 2020
International audienceDuctal carcinoma in situ (DCIS) is a non-invasive type of breast cancer with highly variable potential of becoming invasive and affecting mortality.
Kristensen, Vessela, N, Frigessi, Arnoldo, Geitvik, Gry, Aarum, Skjerven, Helle, Kristine, Lien, Tonje, G, Lingjærde, Ole, Christian, Bathen, Tone, F, Wärnberg, Fredrik, Borgen, Elin, Mælandsmo, Gunhild, Mari, Sauer, Torill, Daidone, Maria, Grazia, Hofvind, Solveig, Bergholtz, Helga, Geisler, Jürgen, Engebråten, Olav, Russnes, Hege, Sørlie, Therese, Garred, Øystein, Naume, Bjørn, Tost, Jörg, Hartmann-Johnsen, Olaf, Johan, Langerød, Anita, Swanson, David, M, Schlichting, Ellen, Børresen-Dale, Anne, Lise   +25 more
core   +2 more sources

A study of the molecular pathology of ductal carcinoma in situ and invasive ductal carcinoma of the breast. [PDF]

, 2005
The biological validity of the histopathological classification of ductal carcinoma in situ (DCIS) of the breast was evaluated in this study by correlating the three histopathological grades of DCIS to immunohistochemical expression of Ki67, p53, cerbB-2,
Rehman, S.
core  

Multi‐regional Organoid Biobank Reveals FAK‐ACSL1‐Driven Doxorubicin‐Resistance and Predictive Biomarkers in Breast Cancer

Advanced Science, EarlyView.
This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu, Zhijun Qin, Jiapeng Yang, Baoyuan Zhang, Manqing Cao, Peng Wang, Zaiqi Wang, Jinghui Cheng, Lei Wang, Hong Liu, Hui Yang   +10 more
wiley   +1 more source

Clinicopathological features and prognostic differences of ductal carcinoma in situ with ductal carcinoma in situ with microinvasion

Di-san junyi daxue xuebao, 2020
Objective To determine the clinicopathological features and prognostic differences between ductal carcinoma in situ (DCIS) and ductal carcinoma in situ with microinvasion (DCIS-MI) of breast cancer. Methods A cohort of 489 female patients with surgically
LIU Jing, ZHANG Ye, YAN Wenting, ZHONG Ling, TAN Xuanni   +4 more
doaj   +1 more source