Results 51 to 60 of about 28,831 (253)

Small scale purification and biophysical characterization of haptoglobin derived from human Cohn fraction IV

Biotechnology Progress, EarlyView.
Abstract Haptoglobin (Hp) is a polymorphic acute phase α‐2 glycoprotein found in plasma that plays a critical role in binding, neutralizing, and removing cell‐free hemoglobin (Hb) from the circulation. Under clinical conditions characterized by high levels of hemolysis, such as in patients with sickle cell disease (SCD), large quantities of cell‐free ...
Shuwei Lu, Mohd Asim Khan, Pedro Cabrales, David C. Irwin, Paul W. Buehler, Andre F. Palmer   +5 more
wiley   +1 more source

Neuro-evolutionary computing approach for an epidemic model of ransomware detection using morlet wavelet neural network with meta-heuristic optimization

Scientific Reports
This paper presents an algorithmic paradigm that will address a malware model in the form of a nonlinear set of differential equations. The neural networks are Morlet wavelet as estimate the state variables of the malware behavior.
Zain Ul Abideen Khan, Muhammad Abid Mughal, Irfan Ul Haq, Muhammad Naeem Aslam, Bouthaina Dammak, Abdullatif Ghallab   +5 more
doaj   +1 more source

Clinicopathological characteristics, treatments, and prognosis of breast ductal carcinoma in situ with microinvasion: A narrative review

Chronic Diseases and Translational Medicine, 2023
Background Ductal carcinoma in situ with microinvasion (DCIS‐MI) is defined as ductal carcinoma in situ (DCIS) with a microscopic invasive focus ≤1 mm in the longest diameter.
Ge Song, Yongqiang Zhang
doaj   +1 more source

Phosphonomethyl (Thio)Phosphonamidite Reagents for the Construction of Phosphonylmethyl Phosphono(Di)Thioate Mono‐ and Diesters

Chemistry – A European Journal, EarlyView.
A set of new phosphonomethyl (thio)phosphonamidite reagents is introduced to generate unprecedented pyrophosphate mimetics. The versatile P(III)‐P(V) reagents allow for the construction of various pyrophosphate isosteres, and the applicability of the chemistry is illustrated in the assembly of a diverse set of stabilized CDP‐glycerol and CDP‐ribitol ...
Pascal Balić, Roy Steneker, Gijsbert A. van der Marel, Jeroen D. C. Codée, Dmitri V. Filippov   +4 more
wiley   +1 more source

Collagen (XI) alpha-1 chain (COL11A1) is an independent prognostic factor in breast ductal carcinoma in situ [PDF]

, 2019
Collagen11A1 (COL11A1) is a fibrillary type collagen constituting a minor component of the extracellular matrix and plays role in tissue tensile strength.
Alkawaz, Abdulbaqi, Ellis, Ian O, Gorringe, Kylie L, Green, Andrew R, Toss, Michael S, Aneja, Ritu, Rakha, Emad A, Miligy, Islam M, Aleskandarany, Mohammed A, Mittal, Karuna   +9 more
core  

Low-grade screen-detected ductal carcinoma in situ progresses more slowly than high-grade lesions:evidence from an international multi-centre study

, 2019
Nuclear grade is an important indicator of the biological behaviour of ductal carcinoma in situ (DCIS). De-escalation of treatment has been suggested for low-grade DCIS.
Fitzpatrick, Patricia, Ronco, G., Tomatis, M., Broeders, M., Hofvind, S., Majek, Ondrej, Frigerio, Alfonso, Bulliard, J.L., Ronco, Guglielmo, Segnan, Nereo, Ascunce, N., Ascunce, Nieves, Frigerio, A., Broeders, Mireille, Hofvind, Solveig, Castellano, Isabella, Segnan, N., Ponti, A., Taplin, S., Anttila, Ahti, Ponti, Antonio, Májek, O., Castellano, I., Bulliard, Jean-Luc, Taplin, Stephen, Lynge, E., Tomatis, Mariano, Lynge, Elsebeth, Fitzpatrick, P., Anttila, A.   +29 more
core   +1 more source

Community Head and Neck Cancer Knowledge, Engagement, Research, and Screening (CHECKERS): Protocol for a Community‐Engaged Approach to Head and Neck Cancer Prevention

Cancer Nexus, EarlyView.
ABSTRACT Introduction Unequal access to care is associated with disparities in prevention, early detection, and outcomes of head and neck cancer (HNC), especially in underserved populations. Community‐engaged research (CEnR) aims to build capacity for community members to address health inequity via bidirectional partnerships with healthcare ...
Nicholas A. Frisco, Vincent M. D'Anniballe, May Z. Gao, Melissa White, Leda Scearce, Dina K. Abouelella, Laura J. Fish, Patrick Warutere, Julius Muchangi, Pauline Mureithi, Trinitia Y. Cannon, Nosayaba Osazuwa‐Peters   +11 more
wiley   +1 more source

The road towards conquering DCIS overtreatment [PDF]

, 2021
The objectives of this thesis, aimed to reduce overtreatment of ductal carcinoma in situ (DCIS) of the breast, were : 1) to evaluate the risk of underestimation after a diagnosis of DCIS and the interrater reliability in the histopathological ...
Groen, E.J.
core  

Molecular Modification Strategies for CO2 Electroreduction to C2+ Products: Classifications, Mechanisms, Advances, and Perspectives

EcoEnergy, EarlyView.
This review comprehensively outlines molecular modification strategies for steering CO2 electroreduction toward C2+ products, including the classification of diverse molecular structures, elucidation of their roles in microenvironment regulation, dissection of C–C coupling pathway engineering, and forward‐looking perspectives on machine learning and ...
Lingling Peng, Hanwen Liu, Tianyou Peng
wiley   +1 more source

LncRNA IPW inhibits growth of ductal carcinoma in situ by downregulating ID2 through miR-29c

Breast Cancer Research, 2022
Background Ductal carcinoma in situ (DCIS) of breast is the noninvasive lesion that has propensity to progress to the malignant form. At present, it is still unknown which lesions can potentially progress to invasive forms.
Ravindra Pramod Deshpande, Sambad Sharma, Yin Liu, Puspa Raj Pandey, Xinhong Pei, Kerui Wu, Shih-Ying Wu, Abhishek Tyagi, Dan Zhao, Yin-Yuan Mo, Kounosuke Watabe   +10 more
doaj   +1 more source