Results 71 to 80 of about 28,831 (253)

Impact of Single‐Cell RNA Reference Selection for the Deconvolution of Breast Cancer Spatial Transcriptomics Datasets

International Journal of Cancer, EarlyView.
ABSTRACT Spot‐based spatial transcriptomics (ST) allows for unbiased gene expression analysis within tissue architecture, overcoming the limitations of single‐cell RNA sequencing (scRNA‐seq) by preserving spatial context. However, the high spatial resolution in ST leads to cellular heterogeneity within spots, requiring computational deconvolution to ...
Stefan Altendorfer, Scott J. Walker, Carsten O. Daub   +2 more
wiley   +1 more source

Cardiometabolic Health and Risk of Breast Cancer Subtypes Among US Black Women

International Journal of Cancer, EarlyView.
ABSTRACT In the United States (US), cardiometabolic conditions and aggressive breast cancers are both more common among Black women than White women. Using data from 57,453 participants in the Black Women's Health Study (BWHS), we prospectively evaluated associations of body mass index (BMI), Type 2 diabetes, hypertension, and hypercholesterolemia with
Yifei Shan, Sarah M. Rothbard, Lynn Rosenberg, Julie R. Palmer, Mollie E. Barnard   +4 more
wiley   +1 more source

Vacuum-assisted biopsy in the era of low-risk ductal carcinoma in situ active monitoring: real world data and implications

Frontiers in Oncology
BackgroundThe short-term oncological safe of active monitoring for ductal carcinoma in situ (DCIS) with low risk (LR-DCIS) of progression to invasive cancers (IC) has been demonstrated. This study evaluates vacuum assisted biopsy (VAB) as diagnostic test
Henrique Lima Couto, Henrique Lima Couto, Carolina Nazareth Valadares, Carolina Nazareth Valadares, Aleida Nazareth Soares, Aleida Nazareth Soares, Bernardo Ferreira de Paula Ricardo, Paola Hartung Toppa, Bertha Andrade Coelho, Bertha Andrade Coelho, Eduardo Carvalho Pessoa, Eduardo Carvalho Pessoa, Vivian Resende, Tereza Cristina de Oliveira Ferreira, Andre Mattar, Andressa Amorim, Paula Clarke, Paula Clarke, Rufo Freitas-Junior, Gabriel de Almeida Silva Junior, Nisha Sharma, Henrique Silva Bartels, Henrique Silva Bartels, Charles Andreé Joseph de Paula, Geraldo Felício Cunha Júnior, Dênia Reis de Paula Oliveira, Bruna Torres Silvestre da Silva, Daniela Rodrigues Siqueira, Marcus Simões Castilho, Marcelo Antonini, Heverton Leal Ernesto de Amorim, Jane Sanglard de Oliveira, Bruna Antunes de Miranda Pires, Douglas de Miranda Pires, Douglas de Miranda Pires, Shirley das Graças Ferreira, Thais Paiva Moraes, Thais Paiva Moraes, Larissa Barbosa Oliveira, Paula Martins Cristina Soares, Vilmar Marques de Oliveira, Annamaria Massaud Rodrigues dos Santos, Annamaria Massaud Rodrigues dos Santos, Annamaria Massaud Rodrigues dos Santos, Rosemar Macedo Souza Rahal, Augusto Tufi Hassan, Augusto Tufi Hassan, Clécio Ênio Murta de Lucena, Giuliano Tosello, Daniel de Araújo Brito Buttros, Daniel de Araújo Brito Buttros, Guilherme Novita, Romana Giordana Ribeiro Saliba, Bárbara Pace Silva Assis Carvalho, Waldeir José de Almeida Junior, Waldeir José de Almeida Junior, Marcellus do Nascimento Moreira Ramos, Ana Carolina Guglielmelli Mendonça, Fernando Marcos Reis   +58 more
doaj   +1 more source

Breast Cancer Outcomes From Ductal Carcinoma In Situ: A Population-Based Cohort Study. [PDF]

Int J Cancer
Women with ductal carcinoma in situ have an elevated risk of subsequent invasive breast cancer, but how this risk evolves over time is unclear. In this population‐based study of ethnically diverse women diagnosed between 2000 and 2022 in New Zealand, the risk of invasive ipsilateral breast cancer persisted beyond 5 years.
Chen Q, Campbell I, Elwood M, Cavadino A, Aye PS, Tin Tin S.   +5 more
europepmc   +2 more sources

Gene Expression Biomarkers for Breast Ductal Carcinoma in Situ Recurrence Prediction

International Journal of Cancer, EarlyView.
ABSTRACT Breast ductal carcinoma in situ (DCIS) is often overtreated due to a lack of robust prognostic and predictive tools. This study aimed to evaluate gene expression in a well‐characterised DCIS cohort to determine their clinical utility as biomarkers for ipsilateral recurrence. RNA was extracted from microdissected tissues from primary DCIS.
Alexandria Un, Sakshi Mahale, David Byrne, Dorothea Lesche, Carlos Martinez‐Perez, Jia‐Min Pang, Maree Pechlivanis, Hugo Saunders, Madawa W. Jayawardana, Tongtong Luo, Sureshni I. Jayasinghe, Tanjina Kader, Lisa Devereux, Puay Hoon Tan, Andrew R. Green, Emad A. Rakha, Arran K. Turnbull, Stephen B. Fox, G. Bruce Mann, Kylie L. Gorringe   +19 more
wiley   +1 more source

Image Vividness Changes due to White‐Boosting on WOLED Display

Journal of the Society for Information Display, EarlyView.
White‐Boosting is a display technique for RGBW WOLED panels that increases peak brightness. This study investigated its effect on perceived image vividness using paired‐comparison experiments. Across three psychophysical experiments, higher White‐Boosting consistently enhanced perceived vividness.
Woojae Jung, Youngshin Kwak, Myong Young Lee, Junghyun Ham   +3 more
wiley   +1 more source

Oncoplastic Surgery Versus Total Breast Reconstruction in Locally Advanced and Multicentric Carcinomas. A Matched Comparative Cohort Study of Oncologic and Aesthetic Outcomes

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background/Objective This study aimed to compare extreme oncoplastic surgery (EO‐partial breast reconstruction for tumors > 5 cm or multicentric lesions) with extreme reconstruction (ER‐mastectomy with reconstruction for tumors >5 cm or multicentric lesions).
Aline Regina Nunes‐Reis, Regis Resende Paulinelli, Rosemar Macedo Sousa Rahal, Luiz Fernando Jubé Ribeiro, Ruffo de Freitas Júnior   +4 more
wiley   +1 more source

The effect of DCIS-associated myoepithelial cells on macrophage phenotype – drivers of DCIS progression [PDF]

Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer, only approximately half of all diagnosed DCIS cases will progress to invasive disease during a woman’s lifetime.
Roozitalab, M
core   +4 more sources

MRI in the differential diagnosis of breast ductal cancerin situ

Zhongguo aizheng zazhi, 2014
Background and purpose: Ductal carcinoma in situ (DCIS), is precursor lesions of invasive breast cancer, belongs to non-systemic ductal lesions, which is similar to other ductal lesions on imaging.
尤超, 顾雅佳, 彭卫军, 毛健, 姜婷婷   +4 more
doaj  

Progression from ductal carcinoma in situ to invasive breast cancer: molecular features and clinical significance

Signal Transduction and Targeted Therapy
Ductal carcinoma in situ (DCIS) represents pre-invasive breast carcinoma. In untreated cases, 25–60% DCIS progress to invasive ductal carcinoma (IDC). The challenge lies in distinguishing between non-progressive and progressive DCIS, often resulting in ...
Jing Wang, Baizhou Li, Meng Luo, Jia Huang, Kun Zhang, Shu Zheng, Suzhan Zhang, Jiaojiao Zhou   +7 more
doaj   +1 more source