Results 91 to 100 of about 28,831 (253)

Rational design of a lipophilic β‐galactosidase‐responsive near‐infrared probe for in vivo imaging of cellular senescence

Smart Molecules, EarlyView.
We developed a lipophilic near‑infrared probe (DCIP‑AcGal) that is specifically activated by senescence‑associated β‑galactosidase. After intravenous injection, it lights up therapy‑induced tumor senescence in living mice. Its optimized lipophilicity also enables blood‑brain barrier crossing to detect natural brain senescence ex vivo. This probe offers
Jiani Huang, Feiyi Chu, Bin Feng, Lin Chen, Peili Cen, Jing Wang, Ying Qu, Lu Hong, Fei Wu, Huanfeng Tian, Yanpeng Fang, Yuanjie Chen, Mei Tian, Wenbin Zeng, Hong Zhang, Yan Zhong   +15 more
wiley   +1 more source

S100A7 (Psoriasin), highly expressed in Ductal Carcinoma (DCIS), is regulated by IFN-gamma in mammary epithelial cells-4

, 2011
Copyright information:Taken from "S100A7 (Psoriasin), highly expressed in Ductal Carcinoma (DCIS), is regulated by IFN-gamma in mammary epithelial cells"http://www.biomedcentral.com/1471-2407/7/205BMC Cancer 2007;7():205-205.Published online 6 Nov ...
Anna Bylander (83715), Maria Yhr (83716), Charlotta Enerbäck (83717), Stina Petersson (83714)   +3 more
core   +1 more source

Comparison of Long‐Term Health‐Related Quality of Life After Mastectomy and Breast Conserving Therapy

World Journal of Surgery, EarlyView.
Long‐term BREAST‐Q outcomes after breast‐conserving therapy (BCT) and mastectomy without reconstruction. Women treated with BCT reported higher psychosocial, sexual, and physical well‐being and greater satisfaction with their breasts than women treated with mastectomy.
Sanna Järvinen, Tiina Jahkola, Hanna Ihalainen, Jussi P. Repo, Susanna Kauhanen, Pauliina Homsy   +5 more
wiley   +1 more source

MDCT Is Very Useful for Evaluating the Spread of DCIS.

, 2009
Introduction: Ductal carcinoma in situ (DCIS) may occasionally spread widely in the duct-lobular segment, thereby complicating the complete resection of the lesion in breast-conserving surgery.
K. Yoshida, H. Takayanagi, I. Kimijima
core   +1 more source

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue, Zachary Nash, Vikram Talaulikar, Shibani Nicum   +3 more
wiley   +1 more source

Systematic assessment of HER2 status in ductal carcinoma in situ of the breast: a perspective on the potential clinical relevance

Breast Cancer Research
In many countries, hormone receptor status assessment of ductal carcinoma in situ (DCIS) is routinely performed, as hormone receptor-positive DCIS patients are eligible for adjuvant anti-hormonal treatment, aiming to reduce the ipsilateral and ...
Mieke R. Van Bockstal, Jelle Wesseling, Ester H. Lips, Marjolein Smidt, Christine Galant, Carolien H. M. van Deurzen   +5 more
doaj   +1 more source

Analysis of tumour-infiltrating lymphocytes reveals two new biologically different subgroups of breast ductal carcinoma in situ

BMC Cancer, 2018
Background Tumour-infiltrating lymphocytes (TILs) have been demonstrated to significantly influence prognosis and response to therapy of invasive breast cancer (IBC).
Marie Beguinot, Marie-Melanie Dauplat, Fabrice Kwiatkowski, Guillaume Lebouedec, Lucie Tixier, Christophe Pomel, Frederique Penault-Llorca, Nina Radosevic-Robin   +7 more
doaj   +1 more source

Combined Contrast Enhanced Mammography and Digital Breast Tomosynthesis in Patients Suspected of Having Breast Cancer: A Prospective Comparison With Digital Mammography and Breast MRI—Findings of the CONTEST Study

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction We aimed to assess diagnostic performance and accuracy for local staging of CEM combined with DBT (CE + DBT) compared to digital mammography (DM) and MRI. Methods Female patients aged 18–70 years with clinical or sonographic suspicion of breast cancer had CE + DBT and breast MRI prior to treatment.
Sarah L. Savaridas, Kulsam Ali, Sarah Vinnicombe, Petra Rauchhaus, Andrew J. Evans, Nisha Sharma, Sally Bolt, Patsy Whelehan   +7 more
wiley   +1 more source

Different distribution of breast cancer subtypes in breast ductal carcinoma in situ and ductal carcinoma in situ with microinvasion

Zhongguo aizheng zazhi, 2018
Background and purpose: Breast ductal carcinoma in situ with microinvasion (DCIS-MI) is considered to be the interim stage in the progression from breast ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC).
李　爽, 郎冠天, 余科达
doaj  

Ductal Carcinoma in Situ (DCIS) and Ductal Carcinoma in Situ with Microinvasion (DCIS-MI) of the Breast [PDF]

, 2002
Purpose: The use of mammographic screening has led to the early detection of breast cancers as well as the increasing incidence of ductal carcinoma in situ (DCIS) and DCIS with microinvasion (MI).
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