Results 111 to 120 of about 29,583 (248)

Systematic assessment of HER2 status in ductal carcinoma in situ of the breast: a perspective on the potential clinical relevance

Breast Cancer Research
In many countries, hormone receptor status assessment of ductal carcinoma in situ (DCIS) is routinely performed, as hormone receptor-positive DCIS patients are eligible for adjuvant anti-hormonal treatment, aiming to reduce the ipsilateral and ...
Mieke R. Van Bockstal, Jelle Wesseling, Ester H. Lips, Marjolein Smidt, Christine Galant, Carolien H. M. van Deurzen   +5 more
doaj   +1 more source

Identification of a “highly-aggressive” DCIS subgroup.

, 2014
DCIS lesions are sub-classified according to the molecular subtypes of adjacent TDLU and IDC (Model 1: TDLU and IDC have the same molecular subtypes; Model 2: TDLU and IDC have different molecular subtypes).
Mary B. Daly (196724), Carolyn M. Slater (590403), Kathy Q. Cai (590404), Karthik Devarajan (215762), Hong Wu (105254), Arthur Patchefsky (590405), Xiaowei Chen (200607), Dana Pape-Zambito (590402), Zhengyu Jiang (211582)   +8 more
core   +1 more source

Rational design of a lipophilic β‐galactosidase‐responsive near‐infrared probe for in vivo imaging of cellular senescence

Smart Molecules, EarlyView.
We developed a lipophilic near‑infrared probe (DCIP‑AcGal) that is specifically activated by senescence‑associated β‑galactosidase. After intravenous injection, it lights up therapy‑induced tumor senescence in living mice. Its optimized lipophilicity also enables blood‑brain barrier crossing to detect natural brain senescence ex vivo. This probe offers
Jiani Huang, Feiyi Chu, Bin Feng, Lin Chen, Peili Cen, Jing Wang, Ying Qu, Lu Hong, Fei Wu, Huanfeng Tian, Yanpeng Fang, Yuanjie Chen, Mei Tian, Wenbin Zeng, Hong Zhang, Yan Zhong   +15 more
wiley   +1 more source

Analysis of tumour-infiltrating lymphocytes reveals two new biologically different subgroups of breast ductal carcinoma in situ

BMC Cancer, 2018
Background Tumour-infiltrating lymphocytes (TILs) have been demonstrated to significantly influence prognosis and response to therapy of invasive breast cancer (IBC).
Marie Beguinot, Marie-Melanie Dauplat, Fabrice Kwiatkowski, Guillaume Lebouedec, Lucie Tixier, Christophe Pomel, Frederique Penault-Llorca, Nina Radosevic-Robin   +7 more
doaj   +1 more source

Initial Localization Is Associated With Margin Status but Not Re‐Excision Outcomes in Breast Conservation Surgery: A Single‐Center Cohort Analysis

World Journal of Surgery, EarlyView.
Positive margins following breast‐conserving surgery (BCS) remain a common cause of re‐operation. Image‐guided localization techniques may reduce margin positivity at index wide local excision (WLE), but their influence on re‐operation outcomes is less well defined.
Ahmed Alosdody, Syed Zahid Afzal Zadie, Habib Gulam Mohemad Charfare, Joyanto Biswas, Yogeshkumar Malam, Kanapathipillai Rajaratnam, Fanourios Georgiades   +6 more
wiley   +1 more source

Prognostic value of ductal carcinoma in situ component in invasive ductal carcinoma of the breast: a Surveillance, Epidemiology, and End Results database analysis

Cancer Management and Research, 2018
San-Gang Wu,1,* Wen-Wen Zhang,2,* Jia-Yuan Sun,2 Zhen-Yu He2 1Department of Radiation Oncology, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen, People’s Republic of China; 2Department of Radiation Oncology, Sun ...
Wu SG, Zhang WW, Sun JY, He ZY
doaj  

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue, Zachary Nash, Vikram Talaulikar, Shibani Nicum   +3 more
wiley   +1 more source

Duktalinė karcinoma in situ: vieno centro patirtis ir 5 metų pooperacinė stebėsena

Lietuvos Chirurgija, 2016
Įvadas Duktalinė karcinoma in situ (DCIS) – heterogeniška liga. Įdiegus profilaktinės patikros programą, nustatomų DCIS atvejų sparčiai daugėja. Medžiaga ir metodai Atlikome retrospektyvią pacienčių, operuotų Nacionaliniame vėžio institute dėl DCIS 2010 ...
Daiva Gudavičienė, Žygimantas Židonis   +1 more
doaj  

Combined Contrast Enhanced Mammography and Digital Breast Tomosynthesis in Patients Suspected of Having Breast Cancer: A Prospective Comparison With Digital Mammography and Breast MRI—Findings of the CONTEST Study

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction We aimed to assess diagnostic performance and accuracy for local staging of CEM combined with DBT (CE + DBT) compared to digital mammography (DM) and MRI. Methods Female patients aged 18–70 years with clinical or sonographic suspicion of breast cancer had CE + DBT and breast MRI prior to treatment.
Sarah L. Savaridas, Kulsam Ali, Sarah Vinnicombe, Petra Rauchhaus, Andrew J. Evans, Nisha Sharma, Sally Bolt, Patsy Whelehan   +7 more
wiley   +1 more source

Agroecology and Transformative Adaptation to Climate Change

Asia Pacific Viewpoint, EarlyView.
ABSTRACT This paper examines transformative adaptation to climate change through the EFICAS Project (Eco‐Friendly Intensification and Climate‐resilient Agricultural Systems) implemented across 12 upland communities in northern Laos from 2014 to 2020.
Jean‐Christophe Castella
wiley   +1 more source