Results 121 to 130 of about 29,583 (248)

Application of deep learning on mammographies to discriminate between low and high-risk DCIS for patient participation in active surveillance trials

Cancer Imaging
Background Ductal Carcinoma In Situ (DCIS) can progress to invasive breast cancer, but most DCIS lesions never will. Therefore, four clinical trials (COMET, LORIS, LORETTA, AND LORD) test whether active surveillance for women with low-risk Ductal ...
Sena Alaeikhanehshir, Madelon M. Voets, Frederieke H. van Duijnhoven, Esther H. lips, Emma J. Groen, Marja C. J. van Oirsouw, Shelley E. Hwang, Joseph Y. Lo, Jelle Wesseling, Ritse M. Mann, Jonas Teuwen, Grand Challenge PRECISION Consortium Steering Group   +11 more
doaj   +1 more source

Fracture risk and initiation of bone‐specific drug therapy following radical cystectomy with urinary diversion

BJU International, EarlyView.
Objectives To assess the risk of fractures among patients with bladder cancer who underwent radical cystectomy (RC) with urinary diversion (UD), compared with matched referents from the general population. Patients/Subjects and Methods We identified 2908 patients who underwent RC between 2011 and 2019, and 13 669 matched referents in a nationwide ...
Mieke Van Hemelrijck, Lars Holmberg, Hans Garmo, Truls Gårdmark, Henrik Kjölhede, Tomas Jerlström, Karin Söderkvist, Anders Ullén, Fredrik Liedberg, Karl Michaëlsson, Christel Häggström   +10 more
wiley   +1 more source

Multimodal genome-wide survey of progressing and non-progressing breast ductal carcinoma in-situ

Breast Cancer Research
Background Ductal carcinoma in-situ (DCIS) is a pre-invasive form of invasive breast cancer (IBC). Due to improved breast cancer screening, it now accounts for ~ 25% of all breast cancers. While the treatment success rates are over 90%, this comes at the
Marija Debeljak, Soonweng Cho, Bradley M. Downs, Michael Considine, Brittany Avin-McKelvey, Yongchun Wang, Phillip N. Perez, William E. Grizzle, Katherine A. Hoadley, Charles F. Lynch, Brenda Y. Hernandez, Paul J. van Diest, Wendy Cozen, Ann S. Hamilton, Debra Hawes, Edward Gabrielson, Ashley Cimino-Mathews, Liliana D. Florea, Leslie Cope, Christopher B. Umbricht   +19 more
doaj   +1 more source

‘Mature’ and ‘Immature’ Death Concepts: Epistemic Injustice and Young Children's Sense‐Making of Death and Dying

Children &Society, EarlyView.
ABSTRACT Most research in Death Studies focuses on adult perspectives. Even when children are the intended focus, this research often remains adult‐centred due to the dominance of developmental psychology. A key concept underpinning this approach is the ‘mature death concept’ (MDC), a normative framework that assumes children's understanding of death ...
Renske Visser, Karin Murris
wiley   +1 more source

Digital analysis of spatial expression of stromal fibroblast activation protein alpha (FAP) in DCIS

Histopathology, EarlyView.
Digital analysis of FAP expression in DCIS revealed a higher FAP level around DCIS with nearby invasion, comparable to invasive carcinoma. High FAP correlated with nuclear grade, papillary DCIS and HER2 subtype, showing prognostic potential. Introduction The presence of non‐progressing ductal carcinoma in situ (DCIS) cases has raised concerns of ...
Ka Long Leung, Ronald C Chan, Conrad H Lee, Ngou‐Men Wong, Monalyn Marabi, Shirley K Jamidi, Yun‐Bi Ni, Julia Y Tsang, Man‐Chi Eric Fu, Dajiang Guo, Gary M Tse   +10 more
wiley   +1 more source

Cooperative Genomic Events Driving Mutant TP53-Driven DCIS Progression

Ductal carcinoma in situ (DCIS) is a mammary lesion characterized by abnormal epithelial cells occurring in mammary ducts while still being confined to the luminal space.
Morrissey, Rhiannon L
core   +1 more source

Curing Capacity of Band‐Bonding Resinous Adhesives Under 3D‐Printed Molar Bands

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Aim To evaluate the curing efficiency of three resin composite adhesives applied beneath 3D‐printed molar bands, by determining their degree of conversion (DC%) at different depths. Materials and Methods Fifteen 3D‐printed metallic band specimens were divided into three groups and bonded with Band Lock Blue (BLB), Optiband Ultra Blue (OBU), or
Sofia Sideri, Maria Dimitriadi, Nearchos Panayi, Spyridon N. Papageorgiou, Theodore Eliades, George Eliades   +5 more
wiley   +1 more source

Can Mammography and Magnetic Resonance Imaging Predict the Preoperative Size and Nuclear Grade of Pure Ductal Carcinoma In Situ?

Diagnostics
Background/Objectives: Thirty to fifty percent of ductal carcinoma in situ (DCIS) cases are high-grade and at risk of progressing to invasive carcinoma. The most important treatment-related risk factor for recurrence is the presence of residual DCIS. The
Hülya Çetin Tunçez, Merve Gürsoy Bulut, Zehra Hilal Adıbelli, Ahmet Bozer, Bülent Ahmet Kart, Demet Kocatepe Çavdar   +5 more
doaj   +1 more source

Does the Oncotype DCIS score impact treatment decisions?

, 2013
91 Background: The Oncotype Dx DCIS Score has been developed and validated for risk recurrence in ductal carcinoma in situ. It is a 12 gene assay performed on an individual patient’s tumor.
Paul R. Gliedman, John Rescigno, Susan K. Boolbol, Sarah Patricia Cate, Ilana Kats, Alyssa Gillego, Manjeet Chadha   +6 more
core   +1 more source

Is the World Getting Smaller? Network‐Driven Heterogeneity in Gravity‐Model Elasticities

The World Economy, EarlyView.
ABSTRACT Gravity models constitute the workhorse of empirical international trade research, yet the temporal stability of their core parameters—distance and GDP elasticities—remains underexplored, particularly in relation to the evolving structure of trade networks.
Zsolt T. Kosztyán, Rita Mátrai, Dénes Kiss   +2 more
wiley   +1 more source