Results 101 to 110 of about 28,831 (253)

Agroecology and Transformative Adaptation to Climate Change

Asia Pacific Viewpoint, EarlyView.
ABSTRACT This paper examines transformative adaptation to climate change through the EFICAS Project (Eco‐Friendly Intensification and Climate‐resilient Agricultural Systems) implemented across 12 upland communities in northern Laos from 2014 to 2020.
Jean‐Christophe Castella
wiley   +1 more source

Prognostic value of ductal carcinoma in situ component in invasive ductal carcinoma of the breast: a Surveillance, Epidemiology, and End Results database analysis

Cancer Management and Research, 2018
San-Gang Wu,1,* Wen-Wen Zhang,2,* Jia-Yuan Sun,2 Zhen-Yu He2 1Department of Radiation Oncology, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen, People’s Republic of China; 2Department of Radiation Oncology, Sun ...
Wu SG, Zhang WW, Sun JY, He ZY
doaj  

Genetic Evolution in BRCA1‐Associated Breast Cancer Reveals Early Driver Mutations Shaping Tumor Features and Prognosis

Cancer Science, EarlyView.
Multi‐region sequencing of 57 BRCA1‐associated breast cancers identified TP53 as the dominant initial driver, defining a triple‐negative subgroup with biallelic BRCA1 loss and elevated genomic instability. TP53 truncating mutations were enriched in BRCA1 carriers and linked to reduced HRD, EMT activation, and a trend toward worse survival.
Li Hu, Zhongwu Li, Qiting Wan, Xingyu Liao, Yaxin Zhang, Qian Liu, Xinyun Ding, Hua Meng, Yifan Wu, Jie Sun, Juan Zhang, Lu Yao, Ye Xu, Yuntao Xie   +13 more
wiley   +1 more source

Duktalinė karcinoma in situ: vieno centro patirtis ir 5 metų pooperacinė stebėsena

Lietuvos Chirurgija, 2016
Įvadas Duktalinė karcinoma in situ (DCIS) – heterogeniška liga. Įdiegus profilaktinės patikros programą, nustatomų DCIS atvejų sparčiai daugėja. Medžiaga ir metodai Atlikome retrospektyvią pacienčių, operuotų Nacionaliniame vėžio institute dėl DCIS 2010 ...
Daiva Gudavičienė, Žygimantas Židonis   +1 more
doaj  

DCIS growth.

, 2018
The deterministic and stochastic necrosis models both result in linear DCIS growth at approximately 1 cm/year (left), even while their cell counts differ by 21% by the end of the simulations (right).
Shannon M. Mumenthaler (752667), Paul Macklin (3475172), Randy Heiland (9979), Ahmadreza Ghaffarizadeh (3475166), Samuel H. Friedman (4884352)   +4 more
core   +1 more source

Long‐term outcome of high‐grade encapsulated papillary carcinoma of the breast: implications for staging and management

Histopathology, EarlyView.
In the original study by Rakha et al., the authors proposed that high‐grade EPC should be considered within an invasive framework regardless of hormone receptor status. In the present study, we adopted a more selective definition of EPC‐A, restricted to tumours showing more adverse features, including high‐grade morphology together with triple‐negative
Milena Stevanovic, Emad Rakha, Ian O. Ellis, Umberto Maccio, Bärbel Papassotiropoulos, Hisham Fansa, Lidija Stevanovic, Heike Frauchiger‐Heuer, Isabell Witzel, Zsuzsanna Varga   +9 more
wiley   +1 more source

Association of Mean Nocturnal Baseline Impedance and AFS EGJ Grading With AET‐Defined Reflux Burden in Korean Patients

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim Diagnosing gastroesophageal reflux disease (GERD) is challenging in borderline acid exposure time (AET). The Lyon Consensus 2.0 defines AET ≥ 6% as pathological reflux; however, East Asian standards often apply a 4% threshold, creating a diagnostic gray zone.
Ye‐Rin Chae, Ga Hee Kim, Ji Soo Moon, Jin Won Chang, Ji Hoon Yoon, Da Hyun Jung, Jun Chul Park, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee   +9 more
wiley   +1 more source

Application of deep learning on mammographies to discriminate between low and high-risk DCIS for patient participation in active surveillance trials

Cancer Imaging
Background Ductal Carcinoma In Situ (DCIS) can progress to invasive breast cancer, but most DCIS lesions never will. Therefore, four clinical trials (COMET, LORIS, LORETTA, AND LORD) test whether active surveillance for women with low-risk Ductal ...
Sena Alaeikhanehshir, Madelon M. Voets, Frederieke H. van Duijnhoven, Esther H. lips, Emma J. Groen, Marja C. J. van Oirsouw, Shelley E. Hwang, Joseph Y. Lo, Jelle Wesseling, Ritse M. Mann, Jonas Teuwen, Grand Challenge PRECISION Consortium Steering Group   +11 more
doaj   +1 more source

Is the World Getting Smaller? Network‐Driven Heterogeneity in Gravity‐Model Elasticities

The World Economy, EarlyView.
ABSTRACT Gravity models constitute the workhorse of empirical international trade research, yet the temporal stability of their core parameters—distance and GDP elasticities—remains underexplored, particularly in relation to the evolving structure of trade networks.
Zsolt T. Kosztyán, Rita Mátrai, Dénes Kiss   +2 more
wiley   +1 more source

Multimodal genome-wide survey of progressing and non-progressing breast ductal carcinoma in-situ

Breast Cancer Research
Background Ductal carcinoma in-situ (DCIS) is a pre-invasive form of invasive breast cancer (IBC). Due to improved breast cancer screening, it now accounts for ~ 25% of all breast cancers. While the treatment success rates are over 90%, this comes at the
Marija Debeljak, Soonweng Cho, Bradley M. Downs, Michael Considine, Brittany Avin-McKelvey, Yongchun Wang, Phillip N. Perez, William E. Grizzle, Katherine A. Hoadley, Charles F. Lynch, Brenda Y. Hernandez, Paul J. van Diest, Wendy Cozen, Ann S. Hamilton, Debra Hawes, Edward Gabrielson, Ashley Cimino-Mathews, Liliana D. Florea, Leslie Cope, Christopher B. Umbricht   +19 more
doaj   +1 more source