Results 101 to 110 of about 29,583 (248)

Progression from ductal carcinoma in situ to invasive breast cancer: molecular features and clinical significance

Signal Transduction and Targeted Therapy
Ductal carcinoma in situ (DCIS) represents pre-invasive breast carcinoma. In untreated cases, 25–60% DCIS progress to invasive ductal carcinoma (IDC). The challenge lies in distinguishing between non-progressive and progressive DCIS, often resulting in ...
Jing Wang, Baizhou Li, Meng Luo, Jia Huang, Kun Zhang, Shu Zheng, Suzhan Zhang, Jiaojiao Zhou   +7 more
doaj   +1 more source

DCIS growth.

, 2018
The deterministic and stochastic necrosis models both result in linear DCIS growth at approximately 1 cm/year (left), even while their cell counts differ by 21% by the end of the simulations (right).
Shannon M. Mumenthaler (752667), Paul Macklin (3475172), Randy Heiland (9979), Ahmadreza Ghaffarizadeh (3475166), Samuel H. Friedman (4884352)   +4 more
core   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Overdiagnosis of ductal carcinoma in situ by grade and definition in population-based screening: A modeling study

Breast
Aim: To estimate ductal carcinoma in situ (DCIS) overdiagnosis overall and by grade in population-based screening and to determine the variation in overdiagnosis estimates by definition.
Keris Poelhekken, Marcel J.W. Greuter, Bert van der Vegt, Monique D. Dorrius, Geertruida H. de Bock   +4 more
doaj   +1 more source

Looking back, looking ahead: Local perspectives on landscape changes and native‐tree restoration in Madagascar

People and Nature, EarlyView.
Abstract Across sub‐Saharan Africa, tree‐based restoration efforts are dominated by exotic tree species due to their rapid biomass accumulation and short‐term economic returns. However, their limited contribution to biodiversity and ecosystem functioning has renewed interest in native‐tree restoration as a more sustainable strategy.
Herimino Manoa Rajaonarivelo, Nancy Lalaharison Rabenantoandro, Dominic Andreas Martin, Estelle Raveloaritiana, Sitraka Andriamampianina, Marie Rolande Soazafy, Botovao Auguste Ramiandrisoa, Maria Joao Santos, O. Sarobidy Rakotonarivo   +8 more
wiley   +1 more source

Organotypic microfluidic breast cancer model reveals starvation-induced spatial-temporal metabolic adaptationsResearch in context

EBioMedicine, 2018
Background: Ductal carcinoma in situ (DCIS) is the earliest stage of breast cancer. During DCIS, tumor cells remain inside the mammary duct, growing under a microenvironment characterized by hypoxia, nutrient starvation, and waste product accumulation ...
Jose M. Ayuso, Amani Gillette, Karina Lugo-Cintrón, Suehelay Acevedo-Acevedo, Ismael Gomez, Molly Morgan, Tiffany Heaster, Kari B. Wisinski, Sean P. Palecek, Melissa C. Skala, David J. Beebe   +10 more
doaj   +1 more source

An integrated forest‐to‐market approach to promote lesser‐known timber species (LKTS) in a domestic timber market in the Congo Basin

PLANTS, PEOPLE, PLANET, EarlyView.
In the Congo Basin, domestic timber markets account for ~40% of timber consumption, yet demand is concentrated on a few high‐value species also sought after on international markets, raising concerns about their long‐term availability. We combine market, wood, and forest data to assess the potential of lesser‐known timber species (LKTS) to support a ...
Mbusa Wasukundi, Marie Caroline Momo Solefack, Chadrack Kafuti, Hans Beeckman, Nils Bourland, Jean‐Pierre Mate Mweru, Benoît Jourez, Kévin Liévens, Michael Monnoye, Félix Laurent, Falonne Osiveri, Robin Doucet, Paul Katembo Vikanza, Silvia Ferrari, Jean Gérard, Nestor Luambua, Joris Van Acker, Jan Van den Bulcke, Wannes Hubau, Tom De Mil   +19 more
wiley   +1 more source

Different distribution of breast cancer subtypes in breast ductal carcinoma in situ and ductal carcinoma in situ with microinvasion

Zhongguo aizheng zazhi, 2018
Background and purpose: Breast ductal carcinoma in situ with microinvasion (DCIS-MI) is considered to be the interim stage in the progression from breast ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC).
李　爽, 郎冠天, 余科达
doaj  

Predicting invasive breast cancer versus DCIS in different age groups [PDF]

, 2014
BackgroundIncreasing focus on potentially unnecessary diagnosis and treatment of certain breast cancers prompted our investigation of whether clinical and mammographic features predictive of invasive breast cancer versus ductal carcinoma in situ (DCIS ...
Jagpreet Chhatwal, Munoz del Rio, Alejandro, Houssam Nassif, Nassif, Houssam, Ayvaci, Mehmet US, Oguzhan Alagoz, Chhatwal, Jagpreet, Elizabeth S Burnside, Kerlikowske, Karla, Mehmet US Ayvaci, Alejandro Munoz del Rio, Karla Kerlikowske, Sickles, Edward A, Edward A Sickles, Alagoz, Oguzhan, Burnside, Elizabeth S   +15 more
core   +2 more sources

Localizable Climate Change Education in Schools: Examining Impacts on Students' Environmental Science Agency

Science Education, EarlyView.
ABSTRACT As our daily lives become increasingly affected by climate change, school‐based science education plays a critical role in preparing students to understand and respond to this global crisis. This cohort controlled quasi‐experimental study conducted in the United States examined whether a localized climate change storyline unit compared to ...
Lindsey Mohan, Emily M. Harris, Jeffrey Snowden, Candice Guy‐Gaytán, Audrey Mohan, Dennis Lee   +5 more
wiley   +1 more source