Results 81 to 90 of about 29,583 (248)

Clinical characteristics of breast ductal carcinoma in situ with microinvasion: a narrative review

Journal of International Medical Research, 2020
Ductal carcinoma in situ (DCIS) with microinvasion (DCIS-MI) is defined as the extension of cancer cells beyond the basement membrane into adjacent tissue with no focus larger than 1 mm or a maximum diameter of less than 1 mm for multiple invasive foci ...
Jie Zheng, Jingjing Yu, Tao Zhou
doaj   +1 more source

Gene Expression Biomarkers for Breast Ductal Carcinoma in Situ Recurrence Prediction

International Journal of Cancer, EarlyView.
ABSTRACT Breast ductal carcinoma in situ (DCIS) is often overtreated due to a lack of robust prognostic and predictive tools. This study aimed to evaluate gene expression in a well‐characterised DCIS cohort to determine their clinical utility as biomarkers for ipsilateral recurrence. RNA was extracted from microdissected tissues from primary DCIS.
Alexandria Un, Sakshi Mahale, David Byrne, Dorothea Lesche, Carlos Martinez‐Perez, Jia‐Min Pang, Maree Pechlivanis, Hugo Saunders, Madawa W. Jayawardana, Tongtong Luo, Sureshni I. Jayasinghe, Tanjina Kader, Lisa Devereux, Puay Hoon Tan, Andrew R. Green, Emad A. Rakha, Arran K. Turnbull, Stephen B. Fox, G. Bruce Mann, Kylie L. Gorringe   +19 more
wiley   +1 more source

Is Ductal Carcinoma In Situ a Precursor or Low‐Risk Variant of Invasive Breast Cancer? A Population Perspective

International Journal of Cancer, EarlyView.
ABSTRACT Ductal carcinoma in situ (DCIS) is usually detected with mammography screening and assumed to be a precursor of invasive ductal cancer (IDC) of the breast. Yet, despite an approximately 10‐fold increase in the rate of DCIS detection and treatment within 20 years following implementation of mammography screening in the United States, IDC ...
Ismail Jatoi, Adalberto M. Filho, Gretchen Gierach, Hyuna Sung, Philip S. Rosenberg   +4 more
wiley   +1 more source

Vacuum-assisted biopsy in the era of low-risk ductal carcinoma in situ active monitoring: real world data and implications

Frontiers in Oncology
BackgroundThe short-term oncological safe of active monitoring for ductal carcinoma in situ (DCIS) with low risk (LR-DCIS) of progression to invasive cancers (IC) has been demonstrated. This study evaluates vacuum assisted biopsy (VAB) as diagnostic test
Henrique Lima Couto, Henrique Lima Couto, Carolina Nazareth Valadares, Carolina Nazareth Valadares, Aleida Nazareth Soares, Aleida Nazareth Soares, Bernardo Ferreira de Paula Ricardo, Paola Hartung Toppa, Bertha Andrade Coelho, Bertha Andrade Coelho, Eduardo Carvalho Pessoa, Eduardo Carvalho Pessoa, Vivian Resende, Tereza Cristina de Oliveira Ferreira, Andre Mattar, Andressa Amorim, Paula Clarke, Paula Clarke, Rufo Freitas-Junior, Gabriel de Almeida Silva Junior, Nisha Sharma, Henrique Silva Bartels, Henrique Silva Bartels, Charles Andreé Joseph de Paula, Geraldo Felício Cunha Júnior, Dênia Reis de Paula Oliveira, Bruna Torres Silvestre da Silva, Daniela Rodrigues Siqueira, Marcus Simões Castilho, Marcelo Antonini, Heverton Leal Ernesto de Amorim, Jane Sanglard de Oliveira, Bruna Antunes de Miranda Pires, Douglas de Miranda Pires, Douglas de Miranda Pires, Shirley das Graças Ferreira, Thais Paiva Moraes, Thais Paiva Moraes, Larissa Barbosa Oliveira, Paula Martins Cristina Soares, Vilmar Marques de Oliveira, Annamaria Massaud Rodrigues dos Santos, Annamaria Massaud Rodrigues dos Santos, Annamaria Massaud Rodrigues dos Santos, Rosemar Macedo Souza Rahal, Augusto Tufi Hassan, Augusto Tufi Hassan, Clécio Ênio Murta de Lucena, Giuliano Tosello, Daniel de Araújo Brito Buttros, Daniel de Araújo Brito Buttros, Guilherme Novita, Romana Giordana Ribeiro Saliba, Bárbara Pace Silva Assis Carvalho, Waldeir José de Almeida Junior, Waldeir José de Almeida Junior, Marcellus do Nascimento Moreira Ramos, Ana Carolina Guglielmelli Mendonça, Fernando Marcos Reis   +58 more
doaj   +1 more source

The Relationships between HER2 Overexpression and DCIS Characteristics

, 2017
The aim of this study was to demonstrate the correlation between human epidermal growth factor receptor 2 (HER2) overexpression and some poor prognosis factors in patients affected by ductal carcinoma in situ (DCIS).
Pavesi, Lorenzo, Da Prada, Gian Antonio, DI CESARE, PAMELA, Battaglia, Andrea, Riccardi, Alberto, Villani, Laura, Frascaroli, Mara   +6 more
core   +1 more source

Levels of miR-126 and miR-218 are elevated in ductal carcinoma in situ (DCIS) and inhibit malignant potential of DCIS derived cells [PDF]

, 2018
A substantial number of ductal carcinoma in situ (DCIS) detected by mammography never progress to invasive ductal carcinoma (IDC) and current approaches fail to identify low-risk patients not at need of adjuvant therapies.
Natali, Cristina, Scatena, Cristian, Marco Galasso, Enzo Bianchini, Bertagnolo, Valeria, Chiara Maria Mazzanti, Enrico Orvieto, Galasso, Marco, Sarah Warner, Vecchione, Andrea, Mazzanti, Chiara Maria, RUGGE, MASSIMO, Massimo Rugge, Naccarato, Giuseppe, Cristian Scatena, Francesca Lessi, Marco Manfrini, Stefano Volinia, Giuseppe Naccarato, Carlo Maria Croce, Silvia Grassilli, Federica Brugnoli, Domenico Reale, Silvano Capitani, Brugnoli, Federica, Valeria Bertagnolo, Adelaide Caligo, Reale, Domenico, Warner, Sarah, Orvieto, Enrico, Grassilli, Silvia, Piubello, Quirino, Caligo, Adelaide, Croce, Carlo Maria, CAPITANI, SILVANO, Lessi, Francesca, Manfrini, Marco, Bianchini, Enzo, Cristina Natali, Volinia, Stefano, Quirino Piubello, Andrea Vecchione   +41 more
core   +1 more source

Abbreviated MRI and Ultrafast MRI of the Breast

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Detection of breast cancer in MRI requires fast, dynamic contrast enhanced (DCE) imaging covering the immediate post‐contrast phase, that is, the first 60 s after contrast injection. This ensures selective depiction of invasive cancer as well as DCIS against an otherwise dark background, that is, before background parenchymal enhancement (BPE)
Teresa Lemainque, Christiane K. Kuhl
wiley   +1 more source

Contrasting DCIS and invasive breast cancer by subtype suggests basal-like DCIS as distinct lesions

, 2020
Ductal carcinoma in situ (DCIS) is a non-invasive type of breast cancer with highly variable potential of becoming invasive and affecting mortality.
Swanson, David M., Daidone, Maria Grazia, Tost, Jörg,, Swanson, David M.,, Frigessi, Arnoldo, Sørlie, Therese, Sørlie, Therese,, Tost, Jörg, Bergholtz, Helga,, Wärnberg, Fredrik,, Frigessi Di Rattalma, Arnoldo, Lien, Tonje Gulbrandsen, Swanson, David, Frigessi, Arnoldo,, Wärnberg, Fredrik, Lien, Tonje G.,, Lien, Tonje G., Daidone, Maria Grazia,, Bergholtz, Helga, Kristensen, Vessela, N, Geitvik, Gry, Aarum, Skjerven, Helle, Kristine, Lien, Tonje, G, Lingjærde, Ole, Christian, Bathen, Tone, F, Borgen, Elin, Mælandsmo, Gunhild, Mari, Sauer, Torill, Daidone, Maria, Grazia, Hofvind, Solveig, Geisler, Jürgen, Engebråten, Olav, Russnes, Hege, Garred, Øystein, Naume, Bjørn, Hartmann-Johnsen, Olaf, Johan, Langerød, Anita, Swanson, David, M, Schlichting, Ellen, Børresen-Dale, Anne, Lise   +39 more
core   +2 more sources

DCIS in BRCA1 and BRCA2 mutation carriers: prevalence, phenotype, and expression of oncodrivers C-MET and HER3 [PDF]

, 2015
Background: Studies report conflicting evidence regarding the existence of a DCIS-associated premalignant path-way in BRCA mutation carriers. We aimed to examine the prevalence, phenotype, and expression of oncodrivers in pure DCIS (pDCIS) and invasive ...
Rosemarie Mick, Katherine L. Nathanson, Holly L. Graves, Rachel L. Yang, Kathreen Lee, Rachel R. Kelz, Brian J. Czerniecki, Susan M. Domchek, Paul J. Zhang   +8 more
core   +1 more source

Low-risk DCIS. What is it? Observe or excise?

, 2021
The issue of overdiagnosis and overtreatment of lesions detected by breast screening mammography has been debated in both international media and the scientific literature.
Pinder, Sarah E.; id_orcid, Thompson, Alastair M., Wesserling, Jelle, Sarah E. Pinder, Alastair M. Thompson, Jelle Wesserling   +5 more
core   +1 more source