Breast DCE-MRI morphological features and semi-quantitative parameters associated with upgrade to invasive carcinoma in biopsyproven DCIS [PDF]
The aim of this study was to identify imaging predictors of upgrade to invasive carcinoma (IC) in patients with biopsy-proven ductal carcinoma in situ (DCIS) based on morphological features and semi-quantitative parameters derived from dynamic contrast ...
Urban Vladimir +9 more
doaj +2 more sources
Is palpable DCIS more aggressive than screen-detected DCIS?
Palpable ductal carcinoma in-situ (pDCIS) is a subset of DCIS presenting with a clinical mass. We hypothesized pDCIS would have more aggressive clinical and pathological features, and higher rates of recurrence and upgrade to invasive disease compared to screen-detected DCIS.We performed a retrospective analysis of female patients (age 28-76) with DCIS
Nina Balac +9 more
openaire +4 more sources
Clinicopathological features, recurrence patterns, and survival outcomes of triple-negative ductal carcinoma in situ: a single-center cohort study [PDF]
Background Triple-negative ductal carcinoma in situ (TN-DCIS) is uncommon, and its prognostic significance remains unclear. We aimed to characterize the clinicopathological features of TN-DCIS and evaluate its association with recurrence outcomes ...
Jingwei Liu +4 more
doaj +2 more sources
DCIS knowledge of women choosing between active surveillance and surgery for low-risk DCIS [PDF]
Background: Ductal carcinoma in situ (DCIS) can progress to invasive breast cancer (IBC), but often never will. As we cannot predict accurately which DCIS-lesions will or will not progress to IBC, almost all women with DCIS undergo breast-conserving ...
E.G. Engelhardt +33 more
doaj +7 more sources
Integrated Multi-Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC. [PDF]
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Zhang N +18 more
europepmc +2 more sources
Ductal Carcinoma In Situ (DCIS) and Microinvasive DCIS: Role of Surgery in Early Diagnosis of Breast Cancer [PDF]
Advances in treatments, screening, and awareness have led to continually decreasing breast cancer-related mortality rates in the past decades. This achievement is coupled with early breast cancer diagnosis.
Veronesi P. +8 more
core +2 more sources
A New Deep Hybrid Boosted and Ensemble Learning-Based Brain Tumor Analysis Using MRI
Brain tumor analysis is essential to the timely diagnosis and effective treatment of patients. Tumor analysis is challenging because of tumor morphology factors like size, location, texture, and heteromorphic appearance in medical images. In this regard,
Mirza Mumtaz Zahoor +6 more
doaj +1 more source
Mucocele like Tumour of the Breast Associated with Ductal Carcinoma in situ and Focal Ductal Carcinoma: What is the Best Approach to these Patients? [PDF]
Mucocele Like Tumours (MLT) of the breast are quite rare neoplasms displaying a broad spectrum. These lesions were considered benign initially. But now, they are believed to be related to atypical ductal hyperplasia, ductal carcinoma, or mucinous ...
Serdar Altinay +3 more
doaj +1 more source
Background: The clinical outcome of breast carcinoma varies in each individual due to its molecular heterogeneity. There is a rising interest in whether the associated ductal carcinoma in-situ in invasive ductal carcinoma of breast affects the prognosis ...
Dhivya Balaiya +2 more
doaj +1 more source
A multi-phase deep CNN based mitosis detection framework for breast cancer histopathological images
The mitotic activity index is a key prognostic measure in tumour grading. Microscopy based detection of mitotic nuclei is a significant overhead and necessitates automation.
Anabia Sohail +4 more
doaj +1 more source

