Results 11 to 20 of about 6,508 (192)

Is palpable DCIS more aggressive than screen-detected DCIS?

Surgery Open Science, 2023
Palpable ductal carcinoma in-situ (pDCIS) is a subset of DCIS presenting with a clinical mass. We hypothesized pDCIS would have more aggressive clinical and pathological features, and higher rates of recurrence and upgrade to invasive disease compared to screen-detected DCIS.We performed a retrospective analysis of female patients (age 28-76) with DCIS
Nina Balac, Robert M. Tungate, Young Ju Jeong, Heather MacDonald, Lily Tung, Naomi R. Schechter, Linda Larsen, Stephen F. Sener, Julie E. Lang, Kirstyn E. Brownson   +9 more
openaire   +4 more sources

DCIS knowledge of women choosing between active surveillance and surgery for low-risk DCIS

Breast
Background: Ductal carcinoma in situ (DCIS) can progress to invasive breast cancer (IBC), but often never will. As we cannot predict accurately which DCIS-lesions will or will not progress to IBC, almost all women with DCIS undergo breast-conserving ...
E.G. Engelhardt, R.S.J.M. Schmitz, M.A. Gerritsma, C.M.T. Sondermeijer, E. Verschuur, J.H.E. Houtzager, R. Griffioen, N. Bijker, R.M. Mann, V. Retèl, F.H. van Duijnhoven, J. Wesseling, E.M.A. Bleiker, Alastair Thompson, Serena Nik-Zainal, Elinor J. Sawyer, Helen Davies, Andrew Futreal, Nicholas Navin, E. Shelley Hwang, Jos Jonkers, Jacco van Rheenen, Fariba Behbod, Esther H. Lips, Marjanka Schmidt, Lodewyk F.A. Wessels, Daniel Rea, Proteeti Bhattacharjee, Hilary Stobart, Deborah Collyar, Donna Pinto, Marja van Oirsouw, S. Alaeikhanehshir, L. Elshof   +33 more
doaj   +7 more sources

The dilemma of DCIS

The Breast, 2007
The increasingly frequent diagnosis of ductal carcinoma in situ (DCIS) presents a major clinical dilemma. Our inability to predict which DCIS will progress to invasive cancer or the time interval in which recurrent DCIS or invasive cancer will occur has resulted in treatments ranging from mastectomy to excision and observation being offered to patients.
Monica, Morrow, Martin J, O'Sullivan
openaire   +2 more sources

Ductal Carcinoma In Situ (DCIS) and Microinvasive DCIS: Role of Surgery in Early Diagnosis of Breast Cancer [PDF]

, 2023
Advances in treatments, screening, and awareness have led to continually decreasing breast cancer-related mortality rates in the past decades. This achievement is coupled with early breast cancer diagnosis.
Veronesi P., Abruzzese G., Galimberti V., Bianchi B., Sacchini V., Corso G., Magnoni F., Di Silvestre S., Alloggio E. A.   +8 more
core   +2 more sources

Essential role of STAT5a in DCIS formation and invasion following estrogen treatment [PDF]

, 2020
Ductal carcinoma in situ (DCIS) is one of the earliest stages of breast cancer (BCa). The mechanisms by which DCIS lesions progress to an invasive state while others remain indolent are yet to be fully characterized and both diagnosis and treatment of ...
Dees, S, Jasmin, J-F, Sotgia, F, Pontiggia, L, Mercier, I, Lisanti, MP   +5 more
core   +1 more source

Immune microenvironment in ductal carcinoma in situ: a comparison with invasive carcinoma of the breast

Breast Cancer Research, 2020
Background The immune microenvironment in ductal carcinoma in situ (DCIS) and its significance are not well established. This study was conducted to evaluate the immune microenvironment of DCIS including the composition of tumor-infiltrating lymphocyte ...
Milim Kim, Yul Ri Chung, Hyun Jeong Kim, Ji Won Woo, Soomin Ahn, So Yeon Park   +5 more
doaj   +1 more source

Different distribution of breast ductal carcinoma in situ, ductal carcinoma in situ with microinvasion, and invasion breast cancer

World Journal of Surgical Oncology, 2012
Background Breast ductal cancer in situ (DCIS) can recur or progress to invasive ductal cancer (IDC), and the interim stage include DCIS with microinvasion (DCIS-Mi).
Wei Zhang, Er-li Gao, Yi-li Zhou, Qi Zhai, Zhang-yong Zou, Gui-long Guo, Guo-rong Chen, Hua-min Zheng, Guan-li Huang, Xiao-hua Zhang   +9 more
doaj   +1 more source

Molecular subtyping of DCIS : heterogeneity of breast cancer reflected in pre-invasive disease [PDF]

, 2010
Background: Molecular profiling has identified at least four subtypes of invasive breast carcinoma, which exhibit distinct clinical behaviour. There is good evidence now that DCIS represents the non-obligate precursor to invasive breast cancer and ...
Jones, J. Louise, J L Jones, Jane Warwick, S E Clark, Warwick, Jane, R L Bowen, Clark, S. E., S W Duffy, Duffy, Stephen W., Bowen, Rebecca, Carpenter, R., J Warwick, R Carpenter   +12 more
core   +1 more source

The clinical significance of oestrogen receptor expression in breast ductal carcinoma in situ

, 2020
Background: Oestrogen receptor (ER) in invasive breast cancer (BC) predicts response to endocrine therapy (ET) and provides prognostic value. In this study, we investigated the value of ER expression in ductal carcinoma in situ (DCIS) in terms of outcome
Macmillan, R. Douglas, Green, Andrew R., Syed, Binafsha M, Oni, Georgette, Khout, Hazem, Tan, Quing, Toss, Michael S, Shiino, Sho, Robertson, John F. R., Rakha, Emad A, Miligy, Islam M   +10 more
core   +1 more source

International variation in management of screen-detected ductal carcinoma in situ of the breast [PDF]

, 2014
Results Twelve countries contributed data from a total of 15 screening programmes, all from Europe except the United States of America and Japan. Among women aged 50-69 years, 7,176,050 screening tests and 5324 screen-detected DCIS were reported. From 21%
Fracheboud, J. (Jacques), Bulliard, J.-L. (Jean-Luc), Fitzpatrick, Patricia, Fracheboud, Jacques, Hofvind, S, Hofvind, S., Von Euler-Chelpin, M. (My), Anttila, A, Kerlikowske, Karla, Bulliard, J.L., Segnan, Nereo, Ponti, A, Ascunce, Nieves, James, T., Taplin, S. (Stephen), Scharpantgen, Astrid, Kerlikowske, K, Hofvind, Solveig, Segnan, N. (Nereo), Segnan, N., Vidal, C. (Carmen), Ponti, A., Salas, D. (Dolores), Taplin, S., James, T, Májek, O., Bulliard, Jean-Luc, Taplin, Stephen, Vidal, C, Segnan, N, Hofvind, S. (Solveig), von Euler-Chelpin, My, Vidal, Carmen, Taplin, S, Kawai, M. (Masaaki), Anttila, A., Scharpantgen, A., Scharpantgen, A. (A.), group, ICSN DCIS Working, Anttila, A. (Ahti), Lynge, E, Ascunce, N, Ponti, A. (Antonio), Salas, Dolores, James, Ted, Májek, O. (Ondřej), Fitzpatrick, P, Vidal, C., Mano, MP, Ascunce, N., Bulliard, JL, Kerlikowske, K., Kawai, M., von Euler-Chelpin, M, Kawai, M, Salas, D., Mano, M.P., Ascunce, N. (Nieves), von Euler-Chelpin, M., Mano, Maria Piera, Majek, O, James, T. (Ted), Anttila, Ahti, Fracheboud, J., Ponti, Antonio, Kawai, Masaaki, Kerlikowske, K. (Karla), Scharpantgen, A, Lynge, E., Lynge, Elsebeth, Májek, Ondřej, Fitzpatrick, P. (Patricia), Fitzpatrick, P., Salas, D, Lynge, E. (Elsebeth), Mano, M.P. (Maria Piera)   +75 more
core   +1 more source