Results 21 to 30 of about 20,385 (185)

Clinicopathological features and prognostic differences of ductal carcinoma in situ with ductal carcinoma in situ with microinvasion

Di-san junyi daxue xuebao, 2020
Objective To determine the clinicopathological features and prognostic differences between ductal carcinoma in situ (DCIS) and ductal carcinoma in situ with microinvasion (DCIS-MI) of breast cancer. Methods A cohort of 489 female patients with surgically
LIU Jing, ZHANG Ye, YAN Wenting, ZHONG Ling, TAN Xuanni   +4 more
doaj   +1 more source

Does Existence of Ductal Carcinoma In Situ Accompanying Invasive Ductal Carcinoma Lead to Different Clinicopathological Features and Clinical Outcome? Report of a Breast Cancer Registry [PDF]

Middle East Journal of Cancer, 2022
Background: Ductal carcinoma in situ (DCIS) is widely recognized as the precursor of invasive ductal carcinoma (IDC). We aimed to compare clinicopathological characteristics and prognosis between IDC with and without coexisting DCIS stratified by ...
Sedigheh Tahmasebi, Baharak Shahin, Masoumeh Ghoddusi Johari, Majid Akrami, Vahid Zanguri, Abdolrasoul Talei, Zahra Keumarsi, Nazanin Karimaghaei   +7 more
doaj   +1 more source

Identification of biomarkers in ductal carcinoma in situ of the breast with microinvasion

BMC Cancer, 2008
Background Widespread use of mammography in breast cancer screening has led to the identification of increasing numbers of patients with ductal carcinoma in situ (DCIS).
Iyama Ken-ichi, Honda Yumi, Ibusuki Mutsuko, Kawasoe Teru, Toyama Tatsuya, Zhang Zhenhuan, Yamamoto Yutaka, Okumura Yasuhiro, Yamashita Hiroko, Iwase Hirotaka   +9 more
doaj   +1 more source

LncRNA IPW inhibits growth of ductal carcinoma in situ by downregulating ID2 through miR-29c

Breast Cancer Research, 2022
Background Ductal carcinoma in situ (DCIS) of breast is the noninvasive lesion that has propensity to progress to the malignant form. At present, it is still unknown which lesions can potentially progress to invasive forms.
Ravindra Pramod Deshpande, Sambad Sharma, Yin Liu, Puspa Raj Pandey, Xinhong Pei, Kerui Wu, Shih-Ying Wu, Abhishek Tyagi, Dan Zhao, Yin-Yuan Mo, Kounosuke Watabe   +10 more
doaj   +1 more source

The dilemma of DCIS

The Breast, 2007
The increasingly frequent diagnosis of ductal carcinoma in situ (DCIS) presents a major clinical dilemma. Our inability to predict which DCIS will progress to invasive cancer or the time interval in which recurrent DCIS or invasive cancer will occur has resulted in treatments ranging from mastectomy to excision and observation being offered to patients.
Monica, Morrow, Martin J, O'Sullivan
openaire   +2 more sources

The natural history of ductal carcinoma in situ (DCIS) in simulation models: A systematic review

Breast, 2023
Objective: Assumptions on the natural history of ductal carcinoma in situ (DCIS) are necessary to accurately model it and estimate overdiagnosis. To improve current estimates of overdiagnosis (0–91%), the purpose of this review was to identify and ...
Keris Poelhekken, Yixuan Lin, Marcel J.W. Greuter, Bert van der Vegt, Monique Dorrius, Geertruida H. de Bock   +5 more
doaj   +1 more source

SmartCon: A Blockchain-Based Framework for Smart Contracts and Transaction Management

IEEE Access, 2022
A smart contract is known to be useful for automating business processes triggered by specific events caused by IoT sensors, data feeds, or other applications.
Muhammad Muneeb, Zeeshan Raza, Irfan Ul Haq, Omair Shafiq   +3 more
doaj   +1 more source

Generation of an Induced Pluripotent Stem Cell‐Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug Treatments

Advanced Healthcare Materials, EarlyView.
Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier, Hristina Koceva, Yann Bachelot, Rosanne W. Koutstaal, Puck B. van Kasteren, Marc Thilo Figge, Christian Eggeling, Alexander Sandy Mosig   +7 more
wiley   +1 more source

TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression

npj Breast Cancer, 2023
Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer. Virtually all women with DCIS are treated, despite evidence suggesting up to half would remain with stable, non-threatening, disease.
Shayin V. Gibson, Elena Tomas Bort, Lucía Rodríguez-Fernández, Michael D. Allen, Jennifer J. Gomm, Iain Goulding, Ulrich auf dem Keller, Andrea Agnoletto, Cathrin Brisken, Barrie Peck, Angus J. Cameron, John F. Marshall, J. Louise Jones, Edward P. Carter, Richard P. Grose   +14 more
doaj   +1 more source

Allogeneic Immune Cell Perfusion Inhibits the Growth of Vascularized 3D In Vitro Tumor Models, Induces Vascular Regression and Desmoplasia, but Promotes Tumor Cell Invasion

Advanced Science, EarlyView.
This study presents a vascularized 3D tumor model to investigate immune–stromal–tumor interactions under allogeneic PBMC perfusion. While immune cells induced tumor shrinkage, they also promoted vascular regression, stromal activation, and cancer cell invasion.
Alexandra Raab, Rasika Daware, Marcelo A. Szymanski de Toledo, Oskar Weber, Dimitris Kapsokalyvas, Twan Lammers, Horst Fischer, Federica De Lorenzi, Fabian Kiessling   +8 more
wiley   +1 more source