Results 41 to 50 of about 20,385 (185)

Boost Approaches in Patients Undergoing Postoperative Radiotherapy

Journal of Surgical Oncology, EarlyView.
ABSTRACT The use of breast conservation surgery for early‐stage breast cancer is common, and adjuvant radiotherapy is often recommended to reduce the risk of ipsilateral breast tumor recurrence. Historical trials have used sequential boost techniques with favorable outcomes with reduction in local recurrence and acceptable cosmetic outcomes.
Abigail Pepin, Neil D. Almeida, Simon Fung‐Kee‐Fung, Megan Kassick, Neil K. Taunk, Gary M. Freedman   +5 more
wiley   +1 more source

Identification of early molecular markers for breast cancer

Molecular Cancer, 2011
Background The ductal carcinoma in situ (DCIS) of the mammary gland represents an early, pre-invasive stage in the development of invasive breast carcinoma.
Schlag Peter M, Schoenegg Winfried, Siedentopf Friederike, Sterner-Kock Anja, Kretschmer Céline, Kemmner Wolfgang   +5 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Resolution of Levodopa/Dopa‐Decarboxylase Inhibitor—Associated Microscopic Colitis with Subcutaneous Foslevodopa/Foscarbidopa: A Case Series and Review of the Literature

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Microscopic colitis (MC) typically presents with chronic, non‐bloody watery diarrhea. Diagnosis requires endoscopy with colonic mucosal biopsies. The etiology is multifactorial, with several medications implicated, although only a few cases have been attributed to oral levodopa/dopa‐decarboxylase inhibitor (LDDCI) therapy.
Romana Hintner, Franziska Eberhardt, Manuela Kofler, Andreas Eigentler, Atbin Djamshidian, Florian Krismer, Anton Hittmair, Heinz Zoller, Valentina Ellinger, Beatrice Heim, Klaus Seppi   +10 more
wiley   +1 more source

Expanding Possibilities for the Use of Writing Genres in Early Elementary Science: Investigating First‐Graders’ Multimodal Sequential Explanations

Science Education, EarlyView.
ABSTRACT This study investigates the outcomes of the implementation of a first grade unit incorporating multiple modes of representation and genre‐based pedagogy to support writing instruction in the genre of sequential explanations. At the end of a 6‐day unit investigating the structure and functions of carnivorous plants, 47 first graders completed a
Rachel E. Wilson, Leslie U. Bradbury
wiley   +1 more source

A stochastic model for evaluating the progression of ductal carcinoma in situ breast cancer using Norwegian breast cancer screening program data

Informatics in Medicine Unlocked
Background: Following widespread mammography screening for breast cancer, the incidence of ductal carcinoma in situ (DCIS) has increased sharply. However, the value of detecting DCIS by screening is uncertain as not all DCIS progresses to invasive breast
Xiaoxue Li, Harald Weedon-Fekjær, Bo Zhang, Sandra J. Lee   +3 more
doaj   +1 more source

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue, Zachary Nash, Vikram Talaulikar, Shibani Nicum   +3 more
wiley   +1 more source

Organotypic microfluidic breast cancer model reveals starvation-induced spatial-temporal metabolic adaptationsResearch in context

EBioMedicine, 2018
Background: Ductal carcinoma in situ (DCIS) is the earliest stage of breast cancer. During DCIS, tumor cells remain inside the mammary duct, growing under a microenvironment characterized by hypoxia, nutrient starvation, and waste product accumulation ...
Jose M. Ayuso, Amani Gillette, Karina Lugo-Cintrón, Suehelay Acevedo-Acevedo, Ismael Gomez, Molly Morgan, Tiffany Heaster, Kari B. Wisinski, Sean P. Palecek, Melissa C. Skala, David J. Beebe   +10 more
doaj   +1 more source

Preoperative Radar Localisation of Impalpable Breast and Axillary Lesions: Initial Experience in an Australian Tertiary Centre

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Image‐guided radar localisation (RL) is a wire‐free alternative to hookwire localisation (HWL) for preoperative localisation of impalpable breast and axillary lesions, with potential logistical and technical advantages. This study assesses clinical utility, accuracy of placement and surgical oncologic outcome metrics for RL using ...
Grace Carpenter, Coralie Simoni, Lucy Lu, Jacqueline Eskander, Tracy Liu, Jennifer Yuill, Sophie Nightingale, Margaret Nguyen, Joseph Paiva   +8 more
wiley   +1 more source

The spectrum of breast in situ papillary carcinomas with invasion and invasive breast carcinomas with papillary features: an overview of histological subtypes and diagnostic challenges. [PDF]

Histopathology
Invasive breast carcinomas with papillary features (IBCP) comprise diverse subtypes with variable architecture, histopathology, and clinical behaviour. This review outlines evolving classification, diagnostic criteria, and treatment implications, highlighting challenges in distinguishing in situ from invasive lesions. Standardised diagnostic approaches
Rakha EA, Tan PH, Raymond WA.
europepmc   +2 more sources