Results 91 to 100 of about 4,166 (290)
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Frontiers in Psychology, 2020 Longitudinal diagnostic classification models (DCMs) with hierarchical attributes can characterize learning trajectories in terms of the transition between attribute profiles for formative assessment.
Wei Tian +3 more
doaj +1 more source
The role of culture, sport and heritage in place shaping
, 2017 Research report commissioned by Department for Culture Media & Sport (DCMS) CASE) programme (the Culture and Sport Evidence (CASE) programme is a joint programme of strategic research led by the Department for Culture, Media and Sport (DCMS) in ...
Evans, Graeme
core
A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity
Advanced Science, EarlyView.This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu +16 more
wiley +1 more source
Advanced Science, EarlyView.CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan +12 more
wiley +1 more source
Young people and gambling in Britain: a critique of the DCMS technical paper No.8
, 2005 Copyright © Masood Zangeneh, Editor-in-Chief, International Journal of Mental Health & AddictionThis report is a brief critique of the report commissioned by the Department of Culture, Media and Sport (DCMS; May-Chahal, Measham, Brannock, Amos, &
Griffiths, Mark D. +2 more
core +1 more source
Isosteric Substitution Enables Rational Design of Two‐Dimensional Energetic Crystals
Advanced Science, EarlyView.Isosteric substitution transforms a classical nitro–amine motif into two‐dimensional aminofurazans with performance beyond TATB. ABSTRACT Two‐dimensional (2D) energetic crystals dissipate mechanical insult via interlayer slip, yet their molecular design space remains narrow.
Linyuan Wen +6 more
wiley +1 more source
AIP Advances, 2016 The all-solid-state electrochromic device (ECD) with the one substrate structure fabricated by the reactive dc magnetron sputtering (DCMS) and cathodic vacuum arc plasma (CVAP) technology has been developed for smart electrochromic (EC) glass application.
Min-Chuan Wang +7 more
doaj +1 more source
Journal of NeuroEngineering and Rehabilitation, 2010 Background Electrical stimulation of the central and peripheral nervous systems is a common tool that is used to improve functional recovery after neuronal injury.
Ahmed Zaghloul
doaj +1 more source
Temporal Interference Stimulation Enhances Neural Regeneration
Advanced Science, EarlyView.Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressotti +15 more
wiley +1 more source