Results 131 to 140 of about 2,262 (257)

Actifensin Evolution in the Human Oral Cavity over the Past 100,000 Years. [PDF]

J Am Chem Soc
Herbst R, Ibrahim A, Hübner A, Knüpfer U, Regestein L, Wiedemann C, Hellmich UA, Warinner C, Stallforth P.   +8 more
europepmc   +1 more source

Chemoenzymatic Synthesis of Heparan Sulfate Oligosaccharides by a Covalent Catch‐and‐Release Approach

Angewandte Chemie, EarlyView.
A glycan having a hydrazide tag enables chemoenzymatic synthesis of HS oligosaccharides. The hydrazide can, under mild acidic conditions, react with an aldehyde‐containing resin to give an immobilized hydrazone that is stable under neutral conditions, allowing washing. The product can be released by transiminolysis using aqueous hydroxylamine to give a
Francesco Palmieri, Chin Huang, Digantkumar Chapla, Kelley W. Moremen, Geert‐Jan Boons   +4 more
wiley   +2 more sources

Light‐Controlled Modulation of 15‐Lipoxygenase‐1 Regulates Intestinal Inflammatory Signaling

Angewandte Chemie, EarlyView.
The developed target‐guided strategy enables the rational design of diazo‐based photoswitchable inhibitors of 15‐lipoxygenase‐1. Distinct molecular architectures program opposite light‐dependent activity, allowing on‐demand control of enzyme inhibition.
Anastasia Louka, Eirini‐Eleni Kalaitzaki, Athanasios Panousis, Sotirios Bonoras, Charalampos Livas, George Froudakis, Ioannis Drygiannakis, Athina Damianaki, George Kolios, Vassilis Valatas, Nikolaos Eleftheriadis   +10 more
wiley   +2 more sources

Primary visual cortex BOLD responses to relative localization of sounds at 7T. [PDF]

iScience
Riberto M, Amadeo MB, Inuggi A, Costagli M, Campus C, Gori M, Morrone MC.   +6 more
europepmc   +1 more source

Generalizable Strategies for the Synthesis of Cereblon‐Recruiting PROTAC Prodrugs

Angewandte Chemie, EarlyView.
Cereblon‐recruiting PROTACs remain challenging to derivatize for prodrug‐based delivery. In this study, three complementary conjugation strategies enabled the efficient synthesis of cleavable PROTAC prodrugs with tunable release kinetics that can be incorporated into a library of PEGylated constructs and bottlebrush prodrugs.
Aiden X. Wang, Bin Liu, Elise M. Ackerman, Yichen Xiang, Hung V.‐T. Nguyen, Yivan Jiang, Angela N. Koehler, Jeremiah A. Johnson   +7 more
wiley   +2 more sources

Stable n‑Type Conduction in WO _<i>x</i> ‑CNT Hybrid Films. [PDF]

ACS Appl Electron Mater
Farooq A, Bignardi L, Stredansky M, Caputo M, Sasikumar S, Bassato F, Ciancio R, Dal Zilio S, Goldoni A, Piseri P, Mazza T, Rubini S, Cepek C.   +12 more
europepmc   +1 more source

White‐Light‐Mediated Imidazole Catalysis Toward Terpene‐Based Thermosets

Angewandte Chemie, EarlyView.
White‐light irradiation enables the photoinitiator‐free curing of fully bio‐based terpene epoxy–anhydride systems. A light‐induced switch in epoxide ring‐opening selectivity leads to colorless, transparent thermosets with enhanced thermomechanical performance, revealing an unexpected pathway for sustainable terpene‐based network formation.
Chenxi Zhang, Sandra Olivero, Alice Mija, Véronique Michelet   +3 more
wiley   +2 more sources

Recipe optimization and SRF test of Cu-compatible Nb[Formula: see text]Sn films by DC magnetron sputtering from a stoichiometric target. [PDF]

Sci Rep
Fonnesu D, Ford D, Chyhyrynets E, Keckert S, Knobloch J, Kugeler O, Lazzari M, Marconato G, Salmaso A, Zubtsovskii A, Pira C.   +10 more
europepmc   +1 more source

Single Nucleotide Polymorphisms, Structural Variants, and Short Tandem Repeats Capture Distinct Signals of Adaptive Divergence in the Atlantic Puffin. [PDF]

Genome Biol Evol
Kersten O, Star B, Anker-Nilssen T, Strøm H, Jakobsen KS, Boessenkool S.   +5 more
europepmc   +1 more source

Signature of Selection Analysis Reveals Candidate Genes Related to Climate Adaptation and Production Traits in Lao Native Goats. [PDF]

J Anim Breed Genet
Le SV, Alexandri P, van der Werf JHJ, Olmo L, Walkden-Brown SW, de Las Heras-Saldana S.   +5 more
europepmc   +1 more source