Results 121 to 130 of about 4,166 (290)

Molecular Mobility of N‐Acetylgalactosamine‐Modified Cyclodextrins on a Polyrotaxane for Highly Efficient Liver Targeting of Antibody Chimeras and Genome‐Editing Ribonucleoproteins

open access: yesAdvanced Science, EarlyView.
Monovalent N‐acetylgalactosamine (GalNAc)‐modified polyrotaxane enables efficient liver targeting by utilizing ligand mobility. The sliding and rotating cyclic components i.e., cyclodextrin in the polyrotaxane dynamically cluster GalNAc moieties, thereby mimicking trivalent interactions with asialoglycoprotein receptors.
Toru Taharabaru   +6 more
wiley   +1 more source

In Situ Confinement of 0D Halometallates Within Deep Eutectic Solvents: From Systematic Screening to Metal‐Tunable Luminescence for Anti‐Counterfeiting Eutectogels

open access: yesAdvanced Science, EarlyView.
We report photostable, photoluminescent deep eutectic solvents (DESs) powered by in situ‐formed zero‐dimensional (0D) halometallates. Stabilized by microenvironment‐controlling hydrogen bond acceptor (HBA) and donor (HBD) networks, these DESs exhibit vibrant, metal ion‐tunable emission (PLQY = 60.2%).
Jeesu Moon   +4 more
wiley   +1 more source

DCMS does science: highlights from the launch of the DCMS Science and Research Advisory Committee (SRAC)

open access: yes, 2010
"Based on the presentations, discussions and Q&A sessions during the SRAC launch event, this publication: highlights the key themes discussed by speakers and launch attendees; summarises the main points from the speakers’ presentations; and, outlines ...

core  

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

open access: yesAdvanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao   +5 more
wiley   +1 more source

Supervising And Collaborating The Networked-Team By Dcms

open access: yes, 2013
The groups of experts in different fields usually need to collaborate in a distributed way such that solutions can be investigated with multi-view and multi-level in analysis and modeling of large-scale, sophisticated systems.
Cai, Zhiming   +2 more
core   +1 more source

Donor Extended Blue TADF Dendrimer for High‐Performance Solution‐Processed OLEDs

open access: yesAdvanced Science, EarlyView.
A dendronized MR‐TADF emitter, DOBNA‐SpAc‐DCz, was designed to improve solubility, hole transport, and exciton dynamics for solution‐processed OLEDs. Incorporation of ter(tert‐butylcarbazole) dendrons decreases ΔEST and accelerates RISC, yielding short delayed lifetimes (∼2 µs).
Mahni Fatahi   +4 more
wiley   +1 more source

DCMS: A Data Analytics and Management System for Molecular Simulation

open access: yes, 2015
Despite the fact that Molecular Simulation systems represent a major research tool in multiple scientific and engineering fields, there is still a lack of systems for effective data management and fast data retrieval and processing. This is mainly due to
Berrada, Meryem
core  

Dual‐Mode Nanoporous SiO2 Memristors with Coexisting Volatile and Nonvolatile Dynamics for Reservoir Computing

open access: yesAdvanced Science, EarlyView.
A nanoporous SiO2 memristor enabling reconfigurable volatile and non‐volatile switching within a single device is demonstrated. The dual‐mode functionality supports both physical reservoir dynamics and synaptic weight storage, allowing unified hardware implementation of reservoir computing for temporal information processing, including image and ...
Bohao Ding   +5 more
wiley   +1 more source

Current and Stray Flux Combined Analysis for Sparking Detection in DC Motors/Generators Using Shannon Entropy

open access: yesEntropy
Brushed DC motors and generators (DCMs) are extensively used in various industrial applications, including the automotive industry, where they are critical for electric vehicles (EVs) due to their high torque, power, and efficiency.
Jorge E. Salas-Robles   +2 more
doaj   +1 more source

Dual‐Module Near‐Infrared Fluorophores Discovery System via Knowledge Transfer

open access: yesAdvanced Science, EarlyView.
This study presents a dual‐module deep learning system for the design of near‐infrared (NIR) fluorophores. A large molecular library is generated and analyzed, leading to the suggestions of promising candidates. The effectiveness of the system is further validated through the synthesis, characterization, and in vivo imaging, demonstrating its potential
Yixin Zhu   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy