Results 101 to 110 of about 190,243 (246)

HMGB1 Assists in Overcoming Cisplatin Resistance in Chemoresistant Human Ovarian Cancer Cells

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Cisplatin is one of the most effective chemotherapeutic agents used in the treatment of ovarian cancer. However, the frequent development of cisplatin resistance remains a significant limitation, leading to therapeutic failure and poor patient outcomes.
Van Huynh   +3 more
wiley   +1 more source

Cross‐lagged assessment between indices of leisure time physical activity and domains of quality of life after electrical stimulation training in persons with spinal cord injury: An exploratory trial

open access: yesPM&R, EarlyView.
Abstract Background An existing association was noted between leisure time physical activity (LTPA) and quality of life (QOL) after spinal cord injury (SCI). Furthermore, electrical stimulation exercise program has been shown to improve domains of QOL.
Ashraf S. Gorgey   +4 more
wiley   +1 more source

NIR‐Responsive Nano‐Integrated Magnesium Phosphate Cement Promotes Bone Regeneration via Osteoblast‐Exosome‐Osteoclast Crosstalk

open access: yesRare Metals, EarlyView.
ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang   +8 more
wiley   +1 more source

Poly(ADP-Ribosyl)ation affects stabilization of CHE-1 protein in response to DNA damage [PDF]

open access: yes, 2011
Post-translation modifications play a crucial role in coordinating the cellular response to DNA damage. Double strand DNA breaks (DSBs) trigger the activation of ATM and Chk2 kinases, which represent the primary transducers in the signalling cascade ...
BACALINI, MARIA GIULIA
core  

The clashing of in situ and pre‐cast technologies—Western trends and local traditions in concrete engineering shaping shell construction in 20th‐century Hungary

open access: yesStructural Concrete, EarlyView.
Abstract After a blossoming pre‐World War II (WWII) period, the concrete construction industry in then‐socialist Hungary existed in a relative isolation from the Western World during the mid‐20th century. In this paper, we focus on the body of work of one of the then newly established state‐owned design offices, IPARTERV, to show how the isolation ...
Orsolya Gáspár, Péter Haba
wiley   +1 more source

Signal‐to‐noise and spatial resolution in in‐line imaging. 3. Optimization using a simple model

open access: yesJournal of Synchrotron Radiation, EarlyView.
Geometrical magnification and X‐ray energy are optimized with respect to spatial resolution, contrast, noise, radiation dose and other image quality characteristics. The optimization is performed using a simple theoretical model of a homogeneous edge feature embedded in a bulk uniform sample, and the resulting generic analytical expressions for image ...
Timur E. Gureyev   +2 more
wiley   +1 more source

Aspects of Radical Gay Liberation Theory in West Germany's Tuntenstreit, 1973–1975

open access: yesGender &History, EarlyView.
ABSTRACT This article examines in depth the theoretical positions of the Tuntenstreit – a major theoretical dispute within the radical West German gay liberation movement in the 1970s. By working through archival material as well as the dispute's fundamental texts, it renders visible its often‐neglected underlying theoretical motifs and, consequently ...
Hauke Branding
wiley   +1 more source

The Wind of Change: Mapping Wind Energy Growth and Multi‐Species Vulnerability in Sardinia, Mediterranean

open access: yesAnimal Conservation, EarlyView.
The rapid expansion of wind energy across the Mediterranean region calls for more advanced tools to assess and mitigate its impacts on biodiversity. In this study, we present an innovative approach combining 13‐year satellite imagery analysis and ecological modelling, to assess the spatiotemporal overlap between wind energy development and habitat ...
Chiara Costantino   +4 more
wiley   +1 more source

Comprehensive Evaluation of OpenCL-based Convolutional Neural Network Accelerators in Xilinx and Altera FPGAs [PDF]

open access: yes, 2016
Deep learning has significantly advanced the state of the art in artificial intelligence, gaining wide popularity from both industry and academia.
Kadetotad, Deepak   +5 more
core  

Nationwide Implementation of Double Reflex Testing for Hepatitis Delta in Spain: Results From the Retrospective Phase of the Spain‐DDR Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Nationwide implementation of double reflex testing for hepatitis delta in Spain markedly increased anti‐HDV and HDV viral load testing between 2022 and 2024, enabling national seroprevalence estimates. Despite this progress, substantial regional heterogeneity persists, highlighting the need for standardised reflex diagnostic protocols.
Ana Alberola   +95 more
wiley   +1 more source

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